The identification of tumor-specific neoantigen (TSN) immunogenicity is crucial to develop peptide/mRNA based antitumoral vaccines and/or adoptive T cell immunotherapies. In silico immunogenicity prediction of candidate ...

Introduction: Hyaline eosinophilic astrocytic inclusion (HEAI) is a rare histological finding in cases with drugresistant epilepsy (DRE). Objectives: To describe two cases of DRE with HEAI and review the literature. Patients ...

Background Glioblastoma is a malignant brain tumor requiring careful clinical monitoring even after primary management. Personalized medicine has suggested the use of various molecular biomarkers as predictors of patient ...

Peripheral nerve sheath tumors are neoplasms with clear morphological diagnostic features and, sometimes, nosological challenges. Their subtypes were described since the very beginning of the history of surgical pathology. ...

Objective: Cerebral amyloid angiopathy-related inflammation (CAA-RI) is a rare and potentially treatable encephalopathy that usually affects people older than 50 years old and has an acute or subacute clinical presentation ...

Systematic evaluation of biomarkers in representative populations is needed to validate their clinical utility. In this work, we assessed the diagnostic performance of cerebrospinal fluid (CSF) neurofilament light chain ...

Masson's tumor or intravascular papillary endothelial hyperplasia (IPEH) is considered a non‐neoplastic lesion. It is probably an unusual exaggerated reorganization of a thrombus. IPEH may be present as a secondary lesion ...