Introducción: El cierre percutáneo del foramen oval permeable (FOP) está establecido
como tratamiento para prevención secundaria de un nuevo accidente cerebrovascular (ACV) en un grupo seleccionado de pacientes. En este ...
Jiménez, Daniel A.; Bagnati, Pablo M.; Flores‐Montes, Rosa Elena; Fernández, María Laura; Zuno‐Reyes, Angélica; Aguillon, David; Alaez‐Verson, Carmen; Becerra‐Solano, Luis E.; Behrens, María Isabel; Branda, Kelly; Chrem, Patricio; Custodio, Nilton; Ducaine, Whitney; Dumois‐Petersen, Sofia; Figuera, Luis; Londoño Castaño, Marisol; Longoria, Erika Mariana; Matute, Esmeralda; Surace, Ezequiel(Elsevier, 2026-05-27)
Autosomal dominant Alzheimer's disease (ADAD) represents a small but impactful subset of Alzheimer's cases. Asymptomatic individuals at genetic risk face substantial personal and family implications when considering ...
Guarnaschelli, María Flor; Marrodán, Mariano; Sosa, Brian Ezequiel; Perez Arana, Carolina I.; Farez, Mauricio Franco; Fiol, Marcela Paula; Ysrraelit, María Célica; Correale, Jorge(SAGE, 2026-04-29)
Background: Progression independent of relapse and MRI activity (PIRMA) is a major contributor to long-term disability in relapsing-remitting multiple sclerosis (RRMS). In Latin America, limited access to high-efficacy ...
Introduction: Sleep and circadian rest-activity rhythm (RAR) disruption may bidirectionally relate to Alzheimer's disease (AD). Down syndrome (DS), the most common genetic cause of AD, presents sleep disorders, yet RAR ...
Freiberger, Rosa Nicole; López, Cynthia Alicia Marcela; Palma, María Belén; Cevallos, Cintia; Sviercz, Franco Agustin; Jarmoluk, Patricio; García, Marcela Nilda; Quarleri, Jorge; Delpino, María Victoria(MDPI, 2026-04-22)
The most common complication of active brucellosis in humans is osteoarticular injury. In the bone marrow microenvironment, mesenchymal stem cells (MSCs) can differentiate into either adipocytes or osteoblasts, and this ...
Rivas, María Elisa; Mattei, Martín; Moya, Diego; MacKo, Richard; MacKo, Charlene; Ameriso, Sebastian Francisco; Dossi, Daiana Elizabeth; Gianella, Matías Gabriel; Best, María Gabriela; Crespos, Marcos José; Hernández, Micaela Anahí(SAGE, 2026-03-06)
Background and aims: Adaptive control ankle robotics is a promising but underexplored strategy for stroke rehabilitation. AMBLE is a wireless impedance-controlled ankle exoskeleton with foot switches that adapt dorsiflexion ...
Objective: To develop regression-based normative data for a set of widely used neuropsychological tests and to provide a freely accessible normative data calculator for use in Buenos Aires, Argentina. Methods: Participants ...
Background: While genetic testing in Movement Disorders (MD) has expanded enormously, access to genetic testing and genetic counseling remains asymmetric at the global scale. Guidance on efficient testing strategies for ...
Morello Garcia, Florentina; Corvalan, Nicolas; Arruabarrena, Micaela Maria; Clarens, Maria Florencia; Keller, Greta; De Los Santos, Loana; Martin, Maria Eugenia; Allegri, Ricardo Francisco; Aguzzoli, Cristiano; Amaral, Livia; Ardohain Cristalli II, Carolina Agata; Bellaver, Bruna; Best, Merci N.; Bloomquist, Madeleine; Fontana, Igor C.; Chen, Kevin; Hernández, Micaela Anahí; Magrath Guimet, Nahuel; Surace, Ezequiel Ignacio; Crivelli, Lucía(Wiley, 2025-12-23)
Background: Different global initiatives aim to support researchers in their fields of study. World Young Leaders in Dementia (WYLD) is an international organization dedicated to connecting and supporting young professionals ...
Background: The accelerated aging process in low‐ and middle‐income countries (LMIC) has led to an increased prevalence of non‐communicable diseases, including dementia, a leading cause of disability in Latin America and ...
Background: Social inequalities are key health determinants shaping Alzheimer’s disease (AD) progression. In dominantly inherited Alzheimer’s disease (DIAD), where genetic causes are established, the influence of socioeconomic ...
Spiousas, Ignacio; Coldeira, María Florencia; Suemoto, Claudia Kimie; Baena, Ana Y.; Salinas‐Contreras, Rosa Maria; Caramelli, Paulo; Brucki, Sonia; Nitrini, Ricardo; Sosa, Ana Luisa; Crivelli, Lucía; Sevlever, Gustavo; Custodio, Nilton; Acosta, Daisy M.; Charamelo, Ana; Salas, Jorge Leon; Delgado, Carolina; Cusicanqui, María Isabel; Jimenez Velazquez, Ivonne Z.; Duque, Lissette; Calandri, Ismael Luis(Alzheimer´s Association, 2025-12-23)
Background: LatAm FINGERS is a feasibility trial aimed at preventing cognitive decline in individuals at risk through lifestyle changes in Latin America, with its objectives aligned with the RE‐AIM (Reach, Effectiveness, ...
Background: Yerba mate (YM), an infusion made from Ilex paraguariensis, is widely consumed in Argentina and other South American countries. Experimental studies have shown that YM enhances antioxidant defenses, increases ...
Vasconcelos Friedlaender, Clarisse; Cruz de Souza, Leonardo; Tonidandel Barbosa, Maira; Braga Gomes, Karina; Tosatti, Jéssica Abdo Gonçalves; Rocha, João Victor de Faria; Melillo Cardoso, Davi; Machado Prates, Marcelo; Lopes, Andre Luis; Silva Vieira, Vitoria; Ribeiro Jeunon, Vinicius; Ferreira de Souza, Letícia Maria; Soares Figueiredo, Lais; Andrades, Andreia; Crivelli, Lucía; Calandri, Ismael Luis; Martin, Maria Eugenia; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Surace, Ezequiel Ignacio(Alzheimer´s Association, 2025-12-21)
Background: Latin America (LA) faces heightened vulnerability to modifiable dementia risk factors. Early identification of at‐risk individuals is crucial for implementing effective preventive strategies. The Free and Cued ...
Background: Ageism, a form of discrimination based on age‐related stereotypes, encompasses both negative (e.g., older adults as burdensome or incapable) and positive (e.g., older adults as wise or nurturing) stereotypes. ...
Suvá, Mariana; Bastón, Juan Ignacio; Wiedenmann, Elisabet Astrid; Pose Ortiz de Rozas, María Belén; Roberto, Jordán; Ghetti, Alberto; Viale, Diego Luis; Moro, Lucia Natalia; Vichera, Gabriel Damián(Elsevier, 2025-09-25)
This study aimed to obtain myostatin (MSTN)-knockout calves, while avoiding the risk of exogenous DNA integration during gene editing. To achieve this, we combined CRISPR/Cas9 ribonucleoprotein gene editing with somatic ...
Rossi, Malco Damián; Stephen, Christopher D.; Damásio, Joana; Pedroso, José Luiz; Kuo, Sheng-Han; R Lin, Chi-Ying; Ojo, Oluwadamilola; El-Jaafary, Shaimaa; Lee, Woong-Woo; Madoev, Harutyun; Barsottini, Orlando G. P.; Srivastava, Achal Kumar; Klein, Christine; van de Warrenburg, Bart P.(Internationa Parkinson and Movement Disorder Society, 2025-07-18)
The landscape of genetic ataxias is influenced by migration, population genetics, consanguinity, and founder effects, resulting in significant regional variation. Within the expanding domain of genetic ataxias, knowledge ...
Background: The Cognitive Function Index (CFI) was developed to identify individuals with Subjective Cognitive Decline (SCD), which is defined by the self‐perception of cognitive impairment, not detected in neuropsychological ...
Pucinelli de Souza Queiroz, Andréia; Pozzolo Pedro, Maria Olivia; Waisman Campos, Marcela; Torales, Julio; Ventriglio, Antonio; Castaldelli-Maia, João Mauricio(MDPI, 2025-07-15)
Cannabis is the most widely consumed illicit substance worldwide, with rising use particularly among adolescents and young adults. Accumulating evidence indicates that chronic cannabis use may negatively impact several ...