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  • Amyloid and anatomical correlates of executive functioning in middle-aged offspring of patients with late-onset Alzheimer's disease 
    Duarte-Abritta, Bárbara; Sánchez, Stella Maris; Abulafia, Carolina; Gustafson, Deborah R.; Vázquez, Silvia; Sevlever, Gustavo Emilio; Castro, Mariana Nair; Fiorentini, Leticia; Villarreal, Mirta Fabiana; Guinjoan, Salvador Martín (Elsevier, 2021-10-30)
    A traditional hallmark of cognitive impairment associated with late-onset Alzheimer´s disease (LOAD) is episodic memory impairment. However, early alterations have been identified in brain regions associated with executive ...
  • An fMRI study of cognitive reappraisal in major depressive disorder and borderline personality disorder 
    De la Peña-Arteaga, Víctor; Berruga-Sánchez, Mercedes; Steward, Trevor; Martínez-Zalacaín, Ignacio; Goldberg, Ximena; Wainsztein, Agustina Edith; Abulafia, Carolina; Cardoner, Narcís; Castro, Mariana Nair; Villarreal, Mirta Fabiana; Menchón, José Manuel; Guinjoan, Salvador Martín; Soriano-Mas, Carles (Cambridge University Press, 2021-09-01)
    Background: One common denominator to the clinical phenotypes of borderline personality disorder (BPD) and major depressive disorder (MDD) is emotion regulation impairment. Although these two conditions have been extensively ...
  • Are Brain Responses to Emotion a Reliable Endophenotype of Schizophrenia? An Image-Based Functional Magnetic Resonance Imaging Meta-analysis 
    Fiorito, Anna M.; Aleman, André; Blasi, Giuseppe; Bourque, Josiane; Cao, Hengyi; Chan, Raymond C.K.; Chowdury, Asadur; Conrod, Patricia; Diwadkar, Vaibhav A.; Goghari, Vina M.; Guinjoan, Salvador Martín; Gur, Raquel E.; Gur, Ruben C.; Kwon, Jun Soo; Lieslehto, Johannes; Lukow, Paulina B.; Meyer-Lindenberg, Andreas; Modinos, Gemma; Quarto, Tiziana; Villarreal, Mirta Fabiana (Elsevier, 2022-06-22)
    Background: Impaired emotion processing constitutes a key dimension of schizophrenia and a possible endophenotype of this illness. Empirical studies consistently report poorer emotion recognition performance in patients ...
  • Assessment of Ataxia Rating Scales and Cerebellar Functional Tests: Critique and Recommendations 
    Perez Lloret, Santiago; Van de Warrenburg, Bart; Rossi, Malco Damián; Rodríguez Blázquez, Carmen; Zesiewicz, Theresa; Saute, Jonas A M; Durr, Alexandra; Nishizawa, Masatoyo; Martínez Martín, Pablo; Stebbins, Glenn T.; Schrag, Anette; Skorvanek, Matej; MDS Rating Scales Review Committee (Wiley-Liss, 2020-10-06)
    Background: We assessed the clinimetric properties of ataxia rating scales and functional tests, and made recommendations regarding their use. Methods: A systematic literature search was conducted to identify the ...
  • Author Correction: AHR is a Zika virus host factor and a candidate target for antiviral therapy 
    Giovannoni, Federico; Bosch, Irene; Manganeli Polonio, Carolina; Torti, María F.; Wheeler, Michael A.; Li, Zhaorong; Romorini, Leonardo; Rodríguez Varela, María Soledad; Rothhammer, Veit; Barroso, Andreia; Tjon, Emily C.; Sanmarco, Liliana M.; Takenaka, Maisa C.; Sadegh Modaresi, Seyed Mohamad; Gutiérrez-Vázquez, Cristina; Ghabdan Zanluqui, Nágela; Barreto Dos Santos, Nilton; Demarchi Munhoz, Carolina; Wang, Zhongyan; Damonte, Elsa B.; Sherr, David; Gehrke, Lee; Schatzmann Peron, Jean Pierre; Garcia, Cybele C.; Quintana, Francisco J. (Nature Publishing Group, 2020-10)
  • Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle 
    Waisman, Ariel; Norris, Alessandra; Costa, Martín Elías; Kopinke, Daniel (Nature Publishing Group, 2021-01-22)
    Skeletal muscle has the remarkable ability to regenerate. However, with age and disease muscle strength and function decline. Myofiber size, which is affected by injury and disease, is a critical measurement to assess ...
  • Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology 
    Morris, John C.; Weiner, Michael W.; Xiong, Chengjie; Beckett, Laurel A.; Coble, Dean; Saito, Naomi; Aisen, Paul S.; Allegri, Ricardo Francisco; Benzinger, Tammie L.S.; Berman, Sarah B.; Cairns, Nigel; Carrillo, María C.; Chui, Helena C.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin R.; Fox, Nick C.; Ghetti, Bernardino; Goate, Alison M. (Oxford University Press, 2022-10-21)
    The extent to which the pathophysiology of autosomal dominant Alzheimer's disease corresponds to the pathophysiology of 'sporadic' late onset Alzheimer's disease is unknown, thus limiting the extrapolation of study findings ...
  • Body mass index, waist circumference, insulin, and leptin plasma levels differentiate between clozapine-responsive and clozapine-resistant schizophrenia 
    Hönig, Guillermo; Daray, Federico M.; Rodante, Demián; Drucaroff, Lucas Javier; Gutiérrez, María Laura; Lenze, Mariela; García Bournissen, Facundo; Wikinski, Silvia (Sage, 2023-06-28)
    Background: Between 25% and 50% of patients suffering from treatment-resistant schizophrenia fail to achieve a clinical response with clozapine. The rapid identification and treatment of this subgroup of patients represents ...
  • Brain training with neurofeedback in patients with mild cognitive impairment: a review study 
    Arroyo-Alvis, Katy Estela; Allegri, Ricardo Francisco; Barceló Martínez, Ernesto (Academia Nacional de Medicina de Venezuela, 2022-06-13)
    Objective: The study aimed to establish the differences in the levels of adaptation, social support, and perceived family functionality according to sex, age, and school grade of a sample of 160 children and adolescents ...
  • Brain volumes quantification from MRI in healthy controls: Assessing correlation, agreement and robustness of a convolutional neural network-based software against FreeSurfer, CAT12 and FSL 
    Chaves, Hernán; Dorr, Francisco; Costa, Martín Elías; Serra, María Mercedes; Fernández Slezak, Diego; Farez, Mauricio Franco; Sevlever, Gustavo Emilio; Yáñez, Paulina; Cejas, Claudia Patricia (Masson, 2020-10-01)
    Background and purpose: There are instances in which an estimate of the brain volume should be obtained from MRI in clinical practice. Our objective is to calculate cross-sectional robustness of a convolutional neural ...
  • Broad-Spectrum Antiviral Effect of Cannabidiol Against Enveloped and Nonenveloped Viruses 
    Marquez, Agostina B.; Vicente, Josefina; Castro, Eliana; Vota, Daiana; Rodríguez Varela, María Soledad; Lanza Castronuovo, Priscila A.; Fuentes, Giselle M.; Parise, Alejandro R.; Romorini, Leonardo; Alvarez, Diego E.; Bueno, Carlos A.; Ramirez, Cristina L.; Alaimo, Agustina; García, Cybele C. (Mary Ann Liebert, 2023-09-08)
    Introduction: Cannabidiol (CBD), the main non-psychoactive cannabinoid of the Cannabis sativa plant, is a powerful antioxidant compound that in recent years has increased interest due to causes effects in a wide range of ...
  • Cardiac Involvement in Movement Disorders 
    Rossi, Malco Damián; Wainsztein, Néstor Adrián; Merello, Marcelo (Wiley, 2021-03-11)
    Background Several conditions represented mainly by movement disorders are associated with cardiac disease, which can be overlooked in clinical practice in the context of a prominent primary neurological disorder. Ob ...
  • celldeath: A tool for detection of cell death in transmitted light microscopy images by deep learning-based visual recognition 
    La Greca, Alejandro; Pérez, Nelba; Castañeda, Sheila; Milone, Paula Melania; Scarafía, María Agustina; Möbbs, Alan Miqueas; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel (Public Library of Science, 2021-06-24)
    Cell death experiments are routinely done in many labs around the world, these experiments are the backbone of many assays for drug development. Cell death detection is usually performed in many ways, and requires time and ...
  • Central Autonomic Network Association With Cardiac Autonomic Sleep-Wake Rhythm in Major Depression and Borderline Personality Disorder 
    Wainsztein, Agustina Edith; Camacho Téllez, Vicente; Abulafia, Carolina; Villarreal, Mirta Fabiana; Soriano-Mas, Carles; Nemeroff, Charles B.; Guinjoan, Salvador Martín; Castro, Mariana Nair (Elsevier, 2021-04-27)
    Background Resting heart rate variability (HRV), a measure of ANS activity, adaptability and health, has been shown to be altered in patients with Major Depressive Disorder (MDD) and Borderline Personality disorder (BPD). ...
  • Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease 
    Johnson, Erik C. B.; Bian, Shijia; Haque, Rafi U.; Carter, E. Kathleen; Watson, Caroline M.; Gordon, Brian A.; Ping, Lingyan; Duong, Duc M.; Epstein, Michael P.; McDade, Eric; Barthélemy, Nicolas R.; Karch, Celeste M.; Xiong, Chengjie; Cruchaga, Carlos; Perrin, Richard J.; Wingo, Aliza P.; Dominantly Inherited Alzheimer Network (Nature Publishing Company, 2023-08-07)
    Alzheimer's disease (AD) pathology develops many years before the onset of cognitive symptoms. Two pathological processes-aggregation of the amyloid-β (Aβ) peptide into plaques and the microtubule protein tau into ...
  • Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease 
    Horie, Kanta; Li, Yan; Barthélemy, Nicolas R.; Gordon, Brian A.; Hassenstab, Jason; Benzinger, Tammie L.S.; Fagan, Anne M.; Morris, John C.; Karch, Celeste M.; Xiong, Chengjie; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Ikeuchi, Takeshi; Kasuga, Kensaku; Noble, James M.; Farlow, Martin R.; Chhatwal, Jasmeer P.; Day, Gregory S.; Schofield, Peter R.; Dominantly Inherited Alzheimer Network (Wiley, 2023-03-16)
    Objective: Identifying cerebrospinal fluid measures of the microtubule binding region of tau (MTBR-tau) species that reflect tau aggregation could provide fluid biomarkers that track Alzheimer's disease related neurofibrillary ...
  • Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis 
    Crivelli, Lucía; Palmer, Katie; Calandri, Ismael Luis; Guekht, Alla; Beghi, Ettore; Carroll, William; Frontera, Jennifer; García-Azorín, David; Westenberg, Erica; Winkler, Andrea Sylvia; Mangialasche, Francesca; Allegri, Ricardo Francisco; Kivipelto, Miia (2022-05)
    Introduction: We conducted a systematic review and meta-analysis of the cognitive effects of coronavirus disease 2019 (COVID-19) in adults with no prior history of cognitive impairment. Methods: Searches in Medline/Web ...
  • Changes in the Care of Neurological Diseases During the First Wave of the COVID-19 Pandemic: A Single Private Center Study in Argentina 
    Calandri, Ismael Luis; Hawkes, Maximiliano Alberto; Marrodán, Mariano; Ameriso, Sebastián Francisco; Correale, Jorge; Allegri, Ricardo Francisco (Frontiers Research Foundation, 2021-09-03)
    Introduction: Healthcare systems are struggling to cope with the rapid evolution of the COVID-19 pandemic. In Argentina, the pandemic is advancing despite prolonged lockdown measures. We aim to analyze the impact of the ...
  • Chemical hypoxia induces apoptosis of human pluripotent stem cells by a NOXA-mediated HIF-1α and HIF-2α independent mechanism 
    Isaja, Luciana; Mucci, Sofía; Vera, Jonathan; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Morris-Hanon, Olivia; Videla Richardson, Guillermo Agustín; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Nature Publishing Group, 2020-10-26)
    Human embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are self-renewing human pluripotent stem cells (hPSCs) that can differentiate to a wide range of specialized cells. Notably, hPSCs enhance their ...
  • Childhood adversity modulates structural brain changes in borderline personality but not in major depression disorder. 
    Camacho Téllez, Vicente; Castro, Mariana Nair; Wainsztein, Agustina Edith; Goldberg, Ximena; De Pino, Gabriela; Costanzo, Elsa; Cardoner, Narcís; Menchón, José Manuel; Soriano-Mas, Carles; Guinjoan, Salvador Martín; Villarreal, Mirta Fabiana (Elsevier, 2024-03-01)
    Adverse childhood experiences (ACEs) negatively affect the function and structure of emotion brain circuits, increasing the risk of various psychiatric disorders. It is unclear if ACEs show disorder specificity with respect ...

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