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Browsing by Author "Garcea, Orlando"

Browsing by Author "Garcea, Orlando"

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  • Absence of latitudinal gradient in oligoclonal bands prevalence in Argentina 
    Negrotto, Laura; Marrodán, Mariano; Fiol, Marcela Paula; Gaitán, María Inés; Ysrraelit, María Célica; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Rojas, Juan Ignacio; Carrá, Adriana; Chertcoff, Aníbal; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Correale, Jorge (Elsevier, 2020-11)
    Background: Like MS prevalence, oligoclonal bands (OCB) frequency seems to follow a latitudinal gradient. Argentina is extensive, latitude-wise, and previous studies have not found an MS prevalence latitudinal gradient. ...
  • Aggressive multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM 
    Kohler, Matías; Kohler, Eduardo; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Correale, Jorge; Marrodán, Mariano; Gaitán, María Inés; Fiol, Marcela Paula; Negrotto, Laura; Ysrraelit, María Célica; Cristiano, Edgardo; Carrá, Adriana; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando (Elsevier, 2021-06-01)
    The objectives of the present study were to describe the frequency of aggressive multiple sclerosis (aMS) as well as to compare clinical and radiological characteristics in aMS and non-aMS patients included in RelevarEM ...
  • The Argentinean multiple sclerosis registry (RelevarEM): Methodological aspects and directions 
    Rojas, Juan Ignacio; Carrá, Adriana; Correale, Jorge; Cristiano, Edgardo; Fernandez Liguori, Nora; Alonso, Ricardo; Alvez Pinheiro, Amelia; Balbuena Aguirre, María Eugenia; Barboza, Andrés G.; Bestoso, Santiago; Blaya, Patricio A.; Burgos, Marcos; Cabrera, Lorena M.; Caride, Alejandro; Carnero Contentti, Edgar; Cohen, Leila; Curbelo, María Celeste; Deri, Norma; Divi, Pablo; Fiol, Marcela Paula; Fracaro, María Eugenia; Gaitán, María Inés; Hryb, Javier Pablo; Jacobo, Miguel; Knorre, Eduardo; Leguizamon, Felisa; Giunta, Diego Hernán; Serena, Marina Alonso; Doldan, María L.; de Lio, Guillermo F.; del V. Liwacki, Susana; López, Pablo Adrián; Luetic, Geraldine G.; Mainella, Carolina; Manzi, Ruben; Marrodán, Mariano; Martínez, Alejandra Diana; Míguez, Jimena S.; Negrotto, Laura; Nofal, Pedro G.; Parada Marcilla, Marcela; Pettinicchi, Juan Pablo; Silva, Berenice Anabel; Silva, Emanuel; Silveira, Facundo Oscar; Steinberg, Judith; Tavolini, Darío; Tizio, Santiago; Tkachuk, Verónica A.; Vázquez, Guido; Volman, Gabriel; Vrech, Carlos; Ysrraelit, María Célica; Zanga, Gisela; Garcea, Orlando; Patrucco, Liliana (Elsevier, 2019-05-15)
    Despite that different registries already exist in various countries in Europe and North America, no ongoing nationwide registry exists in Latin America (LATAM), a region where the disease behaves differently than in other ...
  • Argentinean recommendations on the identification of treatment failure in relapsing remitting multiple sclerosis patients 
    Cristiano, Edgardo; Alonso, Ricardo; Alvez Pinheiro, Amelia; Bacile, Elizabeth A.; Balbuena Aguirre, María Eugenia; Ballario, Carlos; Barboza, Andrés G.; Bestoso, Santiago; Burgos, Marcelo; Cáceres, Fernando; Carnero Contentti, Edgar; Carrá, Adriana; Crespo, Ernesto; Curbelo, María Celeste; Deri, Norma; Fernandez, Jorge; Fernandez Liguori, Nora; Fiol, Marcela Paula; Gaitán, María Inés; Garcea, Orlando; Giunta, Diego Hernán; Halfon, Mario Javier; Hryb, Javier Pablo; Jacobo, Miguel; Kohler, Eduardo; Linares, Ramiro; Luetic, Geraldine G.; Martínez, Alejandra Diana; Míguez, Jimena S.; Nofal, Pedro G.; Patrucco, Liliana; Piedrabuena, Raúl; Rojas, Juan Ignacio; Rotta Escalante, Roberto; Saladino, María Laura; Silva, Berenice Anabel; Sinay, Vladimiro; Steinberg, Judith; Tarulla, Adriana; Vétere, Santiago A.; Villa, Andrés; Vrech, Carlos; Ysrraelit, María Célica; Correale, Jorge (Elsevier, 2018-02-15)
    One of the biggest challenges in multiple sclerosis (MS) is the definition of treatment response/failure in order to optimize treatment decisions in affected patients. The objective of this consensus was to review how ...
  • Clinical and demographic characteristics of male MS patients included in the national registry-RelevarEM. Does sex or phenotype make the difference in the association with poor prognosis? 
    Luetic, Geraldine G.; Menichini, María Laura; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María Célica; Fiol, Marcela Paula; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice Anabel; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica A.; Barboza, Andrés G. (Elsevier, 2021-11-17)
    Background In multiple sclerosis demographics there is a well-known female prevalence and male patients have been less specifically evaluated in clinical studies, though some clinical differences have been reported between ...
  • Consenso sobre la identificación y seguimiento de la esclerosis múltiple secundaria progresiva en Argentina 
    Cristiano, Edgardo; Patrucco, Liliana; Ysrraelit, María Célica; Alonso, Ricardo; Balbuena Aguirre, María Eugenia; Ballario, Carlos; Barboza, Andrés G.; Bestoso, Santiago; Burgos, Marcos; Cáceres, Fernando; Carrá, Adriana; Carnero Contentti, Edgar; Deri, Norma; Fernández-Liguori, Nora; Garcea, Orlando; Hryb, Javier Pablo; Jacobo, Miguel; Kohler, Eduardo; Luetic, Geraldine G.; Mainella, Carolina (Revista de Neurología, 2021-01-01)
    Introducción. Existen diferencias significativas en el diagnóstico, la identificación y el seguimiento de pacientes con esclerosis múltiple secundaria progresiva (EMSP) entre los profesionales de la salud a cargo de su ...
  • Consensus recommendations for family planning and pregnancy in multiple sclerosis in argentina 
    Liguori, Nora Fernández; Alonso, Ricardo; Pinheiro, Amelia Alves; Balbuena Aguirre, María Eugenia; Barboza, Andrés G.; Bestoso, Santiago; Burgos, Marcos; Cáceres, Fernando; Carnero Contentti, Edgar; Carrá, Adriana; Cristiano, Edgardo; Curbelo, María Celeste; Deri, Norma; Fiol, Marcela Paula; Gaitán, María Inés; Garcea, Orlando; Halfon, Mario Javier; Hryb, Javier Pablo; Jacobo, Miguel; José, Gustavo; Knorre, Eduardo; López, Pablo Adrián; Luetic, Geraldine G.; Mainella, Carolina; Martínez, Alejandra Diana; Miguez, Jimena; Nofal, Pedro G.; Pagani Cassará, Fátima; Parada Marcilla, Marcela; Piedrabuena, Raúl; Pita, Cecilia; Quarracino, Cecilia; Rojas, Juan Ignacio; Silva, Berenice Anabel; Sinay, Vladimiro; Steinberg, Judith; Tarulla, Adriana; Tavolini, Darío; Tkachuk, Verónica A.; Tizio, Santiago; Villa, Andrés; Vrech, Carlos; Ysrraelit, María Célica; Patrucco, Liliana (Elsevier, 2020-08)
    Background: Multiple sclerosis (MS) is the most common chronic immune-mediated neurological disorder in young adults, more frequently found in women than in men. Therefore, pregnancy-related issues have become an object ...
  • Consensus recommendations on the management of multiple sclerosis patients in Argentina 
    Cristiano, Edgardo; Rojas, Juan Ignacio; Alonso, Ricardo; Alvez Pinheiro, Amelia; Bacile, Elizabeth A.; Balbuena Aguirre, María Eugenia; Barboza, Andrés G.; Bestoso, Santiago; Burgos, Marcos; Cáceres, Fernando; Carnero Contentti, Edgar; Curbelo, María Celeste; Deri, Norma; Fernandez Liguori, Nora; Gaitán, María Inés; Garcea, Orlando; Giunta, Diego Hernán; Halfon, Mario Javier; Hryb, Javier Pablo; Jacobo, Miguel; Kohler, Eduardo; Luetic, Geraldine G.; Maglio, Ignacio; Martínez, Alejandra Diana; Míguez, Jimena S.; Nofal, Pedro G.; Patrucco, Liliana; Piedrabuena, Raúl; Rotta Escalante, Roberto; Saladino, María Laura; Silva, Berenice Anabel; Sinay, Vladimiro; Tkachuk, Verónica A.; Villa, Andrés; Vrech, Carlos; Ysrraelit, María Célica; Correale, Jorge (Elsevier, 2020-02-15)
    Introduction During the last 20 years, multiple sclerosis (MS) disease has seen major changes with new diagnostic criteria, a better identification of disease phenotypes, individualization of disease prognosis and the ...
  • Core data set for real world data in multiple sclerosis: customization for latin america from a global task force recommendation. 
    Rojas, Juan Ignacio; Gracia, Fernando; Parciak, T.; Alonso, R. N.; Becker, Jefferson; Treviño Frenk, Irene; Alonso Serena, Marina; Giunta, Diego Hernán; Abad, P.; Carnero Contentti, Edgar; Carrá, Adriana; Correa Díaz, Edgar Patricio; Correale, Jorge; Cristiano, Edgardo; Flores, José; Fruns, Manuel; Galleguillos Goiry, Lorna; Garcea, Orlando; Hamuy, Fernando; Lana Peixoto, Marco A.; Navas, Carlos; Papais Alvarenga, Regina; Patrucco, Liliana; Rivera, V.; Tenembaum, S. N.; Ysrraelit, María Célica; Peeters, L.M. (Viguera, 2024-04-01)
    Introduction: The primary objective of the core data set is to reduce heterogeneity and promote harmonization among data sources in EM, thereby reducing the time needed to execute real life data collection efforts. Recently, ...
  • COVID-19 in multiple sclerosis and neuromyelitis optica spectrum disorder patients in Latin America: COVID-19 in MS and NMOSD patients in LATAM 
    Alonso, Ricardo; Silva, Berenice Anabel; Garcea, Orlando; Correa Díaz, Edgar Patricio; Rodrigues Dos Passos, Giordani; Ramirez Navarro, Deyanira A.; Garcia Valle, Luis A.; Rodriguez Salinas, Luis C.; Negrotto, Laura; Luetic, Geraldine G.; Tkachuk, Verónica A.; Míguez, Jimena S.; Hamuy, Fernando; Goiry, Lorna Galleguillos; Ramírez Sánchez, Nicia E.; Burgos, Marcos; Steinberg, Judith; Balbuena Aguirre, María Eugenia; Monterrey Alvarez, Priscilla; Ysrraelit, María Célica (Elsevier, 2021-03-07)
    Background: There is no data regarding COVID-19 in Multiple Sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients in Latin America. Objective: The objective of this study was to describe the clinical ...
  • Disease activity after discontinuation of disease-modifying therapies in patients with multiple sclerosis in Argentina: data from the nationwide registry RelevarEM 
    Zanga, Gisela; Portinari, Carla; Barber, Josefina; Ibañez, Tomas; Brolese, Lucía; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Deri, Norma; Tkachuk, Verónica A.; Vrech, Carlos; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Ysrraelit, María Célica; Marrodán, Mariano; Gaitán, María Inés; Correale, Jorge; RELEVAREM Study Group (Taylor & Francis, 2022-10-02)
    Introduction: The discontinuation of disease-modifying therapies (DMTs) in multiple sclerosis (MS) is commonly seen in real-world settings due to several factors. Area cover: The aim of this study is to describe the ...
  • Estrategias de manejo de terapias de alta eficacia para esclerosis múltiple en la práctica clínica 
    Barboza, Andrés G.; Correale, Jorge; Alonso, Ricardo; Burgos, Marcos; Cáceres, Fernando; Carnero Contentti, Edgar; Carrá, Adriana; Cristiano, Edgardo; Fiol, Marcela Paula; Garcea, Orlando; Luetic, Geraldine G.; Patrucco, Liliana; Piedrabuena, Raúl; Rojas, Juan Ignacio; Silva, Berenice Anabel; Sinay, Vladimiro; Vrech, Carlos; Ysrraelit, María Célica (Elsevier, 2023-06-12)
    Introducción En la actualidad existe un importante número de opciones en terapias modificadoras de la enfermedad en esclerosis múltiple (EM), las cuales pueden ser categorizadas como de baja, moderada y alta eficacia según ...
  • Evaluation of the times of disability progression and related factors in patients with primary progressive multiple sclerosis from Argentina 
    Alonso, Ricardo; Garcea, Orlando; Rojas, Juan Ignacio; Alonso Serena, Marina; Lázaro, Luciana; López, Pablo Adrián; Casas, Magdalena; Tkachuk, Verónica A.; Steinberg, Judith; Barboza, Andrés G.; Martínez, Alejandra Diana; Ysrraelit, María Célica; Correale, Jorge; Marrodán, Mariano; Chertcoff, Aníbal; Deri, Norma; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Pestchanker, Claudia (Elsevier, 2022-01-02)
    Background PPMS (primary progressive multiple sclerosis) patients represent less than 10% of MS patients in Argentina, men and women were similarly affected and most of them had a severe functional impairment. More rapid ...
  • Incidence of COVID-19 after vaccination in people with multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM 
    Rojas, Juan Ignacio; Luetic, Geraldine G.; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María Célica; Fiol, Marcela Paula; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice Anabel; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica A.; Barboza, Andrés G. (Elsevier B. V., 2022-12)
    The objective of the study was to evaluate the incidence of COVID-19 after complete vaccination in people with multiple sclerosis (PwMS) included in the Argentinean MS and NMOSD registry (RelevarEM, NCT03375177). Methods: ...
  • Latin American consensus recommendations on the risk of infections in people with multiple sclerosis treated with disease modifying drugs 
    Silva, Berenice Anabel; Carnero Contentti, Edgar; Becker, Jefferson; Carranza, José I.; Correa Díaz, Edgar Patricio; Galleguillos Goiry, Lorna; Garcea, Orlando; Gracia, Fernando; Hamuy, Fernando; Macías, Miguel Angel; Navas, Carlos; Nuñez, Sebastián; Rojas, Juan Ignacio; Farez, Mauricio Franco; Alonso, Ricardo; López, Pablo Adrián (Elsevier, 2023-06-20)
    Introduction: The emergence of several therapeutic options in multiple sclerosis (MS), which significantly modify the immune system functioning, has led to the need for the consideration of additional factors, such as risk ...
  • Multiple sclerosis and neuromyelitis optica spectrum disorders in Argentina: comparing baseline data from the Argentinean MS Registry (RelevarEM) 
    Rojas, Juan Ignacio; Alonso Serena, Marina; Garcea, Orlando; Patrucco, Liliana; Carrá, Adriana; Correale, Jorge; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Doldan, María L.; Silveira, Facundo Oscar; Alonso, Ricardo; Cohen, Leila; Pita, Cecilia; Silva, Berenice Anabel; Fiol, Marcela Paula; Gaitán, María Inés; Marrodán, Mariano; Negrotto, Laura; Ysrraelit, María Célica; RelevarEM investigators (Springer-Verlag, 2020-06)
    The objective of this study was to describe and compare the baseline epidemiological data of multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients included in RelevarEM (Clinical Trials registry ...
  • Multiple sclerosis care units in Latin America: Consensus recommendations about its objectives and functioning implementation 
    Cristiano, Edgardo; Abad, Patricio; Becker, Jefferson; Carrá, Adriana; Correale, Jorge; Flores, José; Fruns, Manuel; Garcea, Orlando; Garcia Bónitto, Juan; Gracia, Fernando; Hamuy, Fernando; Navas, Carlos; Patrucco, Liliana; Rivera, Víctor M.; Velazquez, Merced; Rojas, Juan Ignacio (Elsevier, 2021-10-15)
    Objective Currently, there are several reasons to promote worldwide the concept of multiple sclerosis care units (MSCU) for a better management of affected patients. Ideally, the MSCU should have some human and technical ...
  • Real-World Effectiveness and Safety of Cladribine in Multiple Sclerosis: Longitudinal Data From the Nationwide Registry in Argentina 
    Rojas, Juan Ignacio; Alonso, Ricardo; Luetic, Geraldine G.; Patrucco, Liliana; Casas, Magdalena; Silva, Berenice Anabel; Miguez, Jimena; Deri, Norma; Vrech, Carlos; Liwacki, Susana; Piedrabuena, Raúl; Silva, Emanuel; Tkachuk, Verónica A.; Burgos, Marcos; Tavolini, Darío; Zanga, Gisela; Alvez Pinheiro, Amelia; Hryb, Javier Pablo; Leguizamon, Felisa; Knorre, Eduardo; López, Pablo Adrián; Martínez, Alejandra Diana; Carrá, Adriana; Alonso Serena, Marina; Cristiano, Edgardo; Correale, Jorge; Garcea, Orlando; Fernández Liguori, Nora; Carnero Contentti, Edgar (Lippincott Williams & Wilkins, 2024-05-23)
    Objective: The aim was to evaluate patient profiles, effectiveness and safety of cladribine (CLAD) in patients with relapsing-remitting multiple sclerosis in Argentina. Methods: This was a substudy included in RelevarEM ...
  • Research priorities in multiple sclerosis in Latin America: A multi-stakeholder call to action to improve patients care: Research priorities in MS in LATAM 
    Rojas, Juan Ignacio; Carnero Contentti, Edgar; Abad, Patricio; Aguayo, Adriana; Alonso, Ricardo; Bauer, Johana; Becker, Jefferson; Bustos, Andrea K.; Carcamo, Claudia A.; Carrá, Adriana; Correa Díaz, Edgar Patricio; Correale, Jorge; Cristiano, Edgardo; Diaz, Alejandro J.; Fernandez Liguori, Nora; Flores, José; Fruns, Manuel; Garcea, Orlando; Ysrraelit, María Célica; LACTRIMS working group (Elsevier, 2021-05-24)
    As human and economic resources are limited, especially in Latin America (LATAM), it is important to identify research priorities to improve multiple sclerosis (MS) patients care in the region. The objective was to generate ...
  • Usage trend of oral drugs for multiple sclerosis patients in Argentina 
    Alonso, Ricardo; Garcea, Orlando; Eizaguirre, María Barbara; Man, Federico; Lopez Bizzo, Abril; Cohen, Leila; Rojas, Juan Ignacio; Patrucco, Liliana; Cristiano, Edgardo; Pita, Cecilia; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Deri, Norma; Miguez, Jimena; Pappolla, Agustín; Lázaro, Luciana; Fernández Liguori, Nora; Correale, Jorge; Carrá, Adriana; Silva, Berenice Anabel (Elsevier, 2020-12-02)
    Introduction: Over the past decade, numerous disease modifying drugs (DMDs) for relapsing- remitting multiple sclerosis (RRMS) have been approved in Argentina. The use of oral DMDs (oDMDs) has increased in recent years, ...

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