Repositorio Institucional Fleni

El Repositorio Institucional Fleni tiene el objetivo reunir, almacenar, preservar y difundir la producción científico-académica de la Institución producto de sus actividades de investigación y docencia, a fin de ponerlas a disposición de la comunidad para su uso, tendiendo a aumentar la visibilidad y la difusión de los documentos generados y colaborar así en la construcción de su memoria institucional.

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Añadido Recientemente

  • Biomechanical Assessment of Orbital Retraction in the Endoscopic Transorbital Approach : A Cadaveric Study 
    Odeibat, Yousef; Gago, Guilherme; Monsalve, Martin; Comeau, Marc-Olivier; Champagne, Pierre-Olivier (Thieme, 2026-02-27)
    Background: The endoscopic transorbital approach (ETOA) provides minimally invasive access to the skull base but requires orbital retraction across key zones to establish a surgical corridor. Retraction is essential for ...
  • Standardizing Surgical Freedom Measurement : A Tool for Objective Comparison of Skull Base Approaches 
    Odeibat, Yousef; Gago, Guilherme; Monsalve, Martin; Agosti, Edoardo; Champagne, Pierre-Olivier (Thieme, 2026-02-27)
    Background: Surgical freedom quantifies proximal instrument maneuverability with fixed distal targets, critical for comparing neurosurgical approaches. Current methods lack standardization, using different geometries without ...
  • Prognostic significance of CDKN2A/B hemizygous deletion in IDH-mutant astrocytomas : a systematic review and meta-analysis 
    Nakasu, Satoshi; Deguchi, Shoichi; Mezmezian, Mónica Beatriz; Mitsuya, Koichi; Notsu, Akifumi; Nakasu, Yoko (Springer-Verlag Tokyo, 2026-03-17)
    The prognostic significance of CDKN2A/B hemizygous deletion (HemD) in IDH-mutant astrocytomas (A-IDHm) remains unclear. We conducted a systematic review and WHO grade-specific meta-analysis of primary tumors following the ...
  • Characterization of individuals fulfilling clinical criteria for limbic-predominant age-related TDP43 encephalopathy (LATE) in a tertiary memory clinic 
    Groot, Colin; Calandri, Ismael Luis; Bader, Ilse; Bocancea, Diana I.; de Bruin, Hannah; Carrigan, Maria; Kamps, Suzie; de Koning, Lotte A.; Mastenbroek, Sophie E.; Rikken, Roos M.; van Tol, Bastiaan G. J.; Vermeiren, Marie R.; Wesseling, Alex; Xia, Ye; Teunissen, Charlotte E.; van de Giessen, Elsmarieke; Barkhof, Frederik; Jonkman, Laura E.; van der Lee, Sven J.; de Boer, Casper (Wiley Periodicals LLC on behalf of Alzheimer's Association, 2026-01-07)
    Background Limbic-predominant age-related TDP-43 encephalopathy (LATE) clinically mimics and often co-occurs with Alzheimer's disease (AD). Expert consensus criteria have been proposed for the LATE clinical diagnosis, ...
  • Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN-TU-001 trial 
    McCullough, Austin; Chen, Charles D.; Gordon, Brian A.; Joseph-Mathurin, Nelly; Jack Jr, Clifford R; Koeppe, Robert; Hornbeck, Russ; Koudelis, Deborah; McKay, Nicole S.; Hobbs, Diana A.; Flores, Shaney; Keefe, Sarah J.; Aggarwal, Neelum T.; Allegri, Ricardo Francisco; Berman, Sarah B.; Bird, Thomas; Black, Sandra E.; Brooks, William S.; Chhatwal, Jasmeer P.; Day, Gregory S.; DIAN‐TU Study Team (Wiley, 2025-07)
    Introduction: Monoclonal anti-amyloid therapies are now accessible, but how these treatments influence changes within the brain is still not clear. We investigated overall and regional change in amyloid removal, glucose ...

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