Repositorio Institucional FLENI: Envíos recientes

  • Factors for Rituximab Refractoriness in AQP4-IgG+ NMOSD: A Cohort Study 
    Marrodán, Mariano; Piedrabuena, María Agustina; Zárate, María Agustina; Rodríguez Murúa, Sofía; Surace, Ezequiel Ignacio; Farez, Mauricio Franco; Fiol, Marcela Paula; Ysrraelit, María Célica; Correale, Jorge (Wiley Periodicals, 2025-08)
    Objective: Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin-4 antibodies (AQP4-IgG). Rituximab, a CD20+ B-cell depleting ...
  • Integrated Workflow for Drug Repurposing in Glioblastoma: Computational Prediction and Preclinical Validation of Therapeutic Candidates 
    Gonzalez, Nazareno; Pérez Küper, Melanie; Garcia Fallit, Matías; Peña Agudelo, Jorge A.; Candia, Alejandro Nicola; Suarez Velandia, Maicol; Romero, Ana Clara; Videla Richardson, Guillermo Agustín; Candolfi, Marianela (MDPI, 2025-06-13)
    Background: Glioblastoma (GBM) remains a significant challenge in oncology due to its resistance to standard treatments including temozolomide. This study aimed to develop and validate an integrated model for predicting ...
  • Targeting FOXP3 in glioblastoma: Blockade of tumor intrinsic effects boosts response to chemo-radiotherapy 
    Garcia Fallit, Matías; Peña Agudelo, Jorge A.; Nicola Candia, Alejandro J.; Gonzalez, Nazareno; Pérez Küper, Melanie; Zampini, Yamila; Romero, Ana Clara; Sobarzo, Cristian; Sánchez Rojas, Ivana; Durán, Hebe; Perona, Marina; Ripari, Luisina Belén; Videla Richardson, Guillermo Agustín; Zanetti, Flavia A.; Lozano, Teresa; Casares, Noelia; Lasarte, Juan José; Candolfi, Marianela (Elsevier, 2025-06-27)
    Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. Although this disease carries a dismal prognosis due to its highly invasive nature and resistance to therapy, no significant therapeutic advances ...
  • Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome 
    Fissolo, Nicolás; Schaedelin, Sabine; Villar, Luisa M.; Lünemann, Jan D.; Correale, Jorge; Rejdak, Konrad; Schwab, Nicholas; Vilaseca, Andreu; Held, Friederike; García-Merino, Antonio; Bittner, Stefan; Trojano, María; Furlan, Roberto; Tumani, Hayrettin; Pérez-Miralles, Francisco; Rosenstein, Igal; Galimberti, Daniela; Álvarez-Bravo, Gary; Thouvenot, Eric; Llufriu, Sara (American Medical Associatio, 2025-07-01)
    Importance: Understanding the risk factors for symptom development will allow clinicians to stratify people with radiologically isolated syndrome (pwRIS) more effectively and tailor their management strategies accordingl ...
  • Infusiones de ketamina a dosis subanestésicas en la depresión mayor resistente al tratamiento: protocolo de aplicación en un hospital público de Argentina 
    Dines, Micaela; Bulacia, Adriana; Bamondez, Paloma; Vega, Irene Luis; Montenegro, Micaela; Díaz, Pablo Germán; Oyhamburu, Paula; Ramos, Ana Laura; Ambrosio, Florencia; Vázquez, Gustavo; Pereyra, Monica; Pereyra, Hugo; Cichello, Cynthia; Ríos Merino, Laura Natalia (Polemos, 2025-07-10)
    La depresión mayor resistente al tratamiento (DMRT) representa un desafío significativo en psiquiatría, dada la limitada respuesta a las terapias convencionales. La ketamina endovenosa (EV) a dosis subanestésicas ha emergido ...
  • Peer Reviewing a Case-Based Manuscript in Movement Disorders Neurology 
    Di Luca, Daniel G.; Prasad, Shweta; Kirby, Alana; Merello, Marcelo; Bhatia, Kailash P.; Goetz, Christopher (Wiley, 2025-05-05)
  • Lifetime Risk of First Symptomatic ICH or Seizure in Familial Cerebral Cavernous Malformations: A Multicenter Patient Data Analysis 
    Dammann, Philipp; Santos, Alejandro N.; Mavarani, Laven; Guey, Stéphanie; Chabriat, Hugues; Herve, Dominique; Croft, Jacob; Renteria, Mellisa; Jang, David; Zhang, Jun; Li, Da; Wu, Zhen; Weng, Jian-Cong; Petracca, Antonio; Fusco, Carmela; D'Agruma, Leonardo; Cervio, Andrés Eduardo; Villamil, Facundo; Rosales, Julieta Soledad; Brain Vascular Malformation Consortium Cerebral Cavernous Malformation Investigator Group (Lippincott Williams & Wilkins, 2025-06-10)
    Background and objectives: Familial cavernous malformations (FCMs) are vascular lesions that pose a lifelong risk of symptomatic hemorrhage (SH) and seizures, yet their natural history remains unclear. This study aims to ...
  • Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease 
    Chen, Charles D.; Franklin, Erin E.; Li, Yan; Joseph-Mathurin, Nelly; Burns, Aime L.; Hobbs, Diana A.; McCullough, Austin A.; Schultz, Stephanie A.; Xion, Chengjie; Wang, Guoqiao; Masellis, Mario; Robin Hsiung, Ging-Yuek; Gauthier, Serge; Berman, Sarah B.; Roberson, Erik D.; Honig, Lawrence S.; Clarnette, Roger; Allegri, Ricardo Francisco; DIAN-TU Study Team; DIAN-Obs Study Team (Springer Verlag, 2025-06-03)
    Clinical trials of anti-amyloid-β (Aβ) monoclonal antibodies in Alzheimer disease (AD) infer target engagement from Aβ positron emission tomography (PET) and/or fluid biomarkers such as cerebrospinal fluid (CSF) Aβ42/40. ...
  • Embolización Selectiva como tratamiento de la capsulitis adhesiva. Reporte de un caso 
    Bertoni, Hernán Gabriel; Rosado, Martín; Cavallo, Jorge (Sociedad Argentina de Reumatología, 2025-03-29)
    La capsulitis adhesiva constituye una patología del hombro que genera rigidez y restricción dolorosa al movimiento activo y pasivo de esta articulación. Es habitual su evolución crónica, generando limitaciones funcionales ...
  • Reevaluating triptan contraindications: A follow-up survey among Latin American neurologists 
    Bancalari, Ernesto; Robblee, Jennifer; Goicochea, María Teresa; Muñoz, Joe; Peres, Mario F.P.; Velez, Karina (Sage, 2025-06-04)
    ObjectiveSurvey Latin American (LATAM) neurologists on their comfort with prescribing triptans in the setting of common contraindications. BackgroundTriptans are associated with multiple contraindications due to 5-HT1B-mediated ...
  • Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research 
    Ángel, María José; Mizraji, Gabril F.; Gómez-Arévalo, Gonzalo; Garcia, Silvia; González-Toledo, María Eugenia; Avale, Elena; Paez-Paz, Indiana; Falzone, Tomás; Holubiec, Mariana; Peralta, María C.; Castano, Federico; Sevlever, Gustavo Emilio; Mezmezian, Mónica Beatriz; Marras, Connie; Gershanik, Oscar; Chade, Anabel; Pardo, Carolina; Rellan, Florencia; Campastri, Ana; Couto, Blas (Elsevier, 2025-05-15)
    Background: Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are neurodegenerative disorders with disabling postural instability, falls and cognitive impairment associated with 4-repeat tau protein ...
  • Cambios en nivel de la lesión de pacientes pediátricos con trauma medular 
    Ares, Julieta Jael; Gatti, Marcelo Andrés; Benett, Nalia Milagros; Monzón, Estela Maris; Andreu, Mauro Federico (Sociedad Chilena de Pediatría, 2025-06-25)
    La lesión medular traumática (LMT) es poco frecuente en población pediátrica, con un significativo impacto en la calidad de vida. Existe escasa literatura en esta población que documente la recuperación neurológica en los ...
  • Patent foramen ovale: is a change in the diagnostic paradigm necessary? 
    Magariños, Eduardo; Scuteri, Antonio; Romano, Ariel; Herrera Paz, Juan José; Razzini, Sofía; Lagos, Roberto; Colombero, Darío; Pujol Lereis, Virginia Andrea; Ameriso, Sebastián Francisco (Fundación Revista Medicina (Buenos Aires), 2025)
    The patent foramen ovale has been a well-known medical entity for a long time. With the advent of new diagnostic tools, the methodology for evaluating patients with stroke and suspected patent foramen ovale is evolving. ...
  • Development of early progression independent of relapse activity significantly impacts on disability accumulation in patients with multiple sclerosis 
    Zárate, María Agustina; Marrodán, Mariano; Piedrabuena, María Agustina; Fiol, Marcela Paula; Ysrraelit, María Célica; Correale, Jorge (Elsevier, 2025-05-14)
    Background: Disability accumulation in multiple sclerosis (MS) is driven by relapse-associated worsening (RAW) and progression independent of relapse activity (PIRA). Early PIRA (EP), occurring within five years of disease ...
  • Dementia research in low-income and middle-income countries - a view from Latin America 
    Allegri, Ricardo Francisco (Nature, 2025-07-29)
    Dementia research, and research in general, has historically been scarce in low-income and middle-income countries (LMICs). However, a high burden of dementia is faced by these regions, with a higher prevalence compared ...
  • Large-scale profiling of antibody reactivity to glycolipids in patients with Guillain-Barré syndrome 
    Thomma, Robin C.M.; Halstead, Susan K.; de Koning, Laura C; Wiegers, Evelin E.J.A.; Gourlay, Dawn S.; Tio-Gillen, Anne P.; van Rijs, Wouter; Andersen, Henning; Antonini, Giovanni; Arends, Samuel; Attarian, Shahram; Barroso, Fabio Adrián; IGOS consortium (Oxford University Press, 2025-03-17)
    Guillain-Barré syndrome is an acute polyradiculoneuropathy in which preceding infections often elicit the production of antibodies that target peripheral nerve antigens, principally gangliosides. Anti-ganglioside antibodies ...
  • Hereditary Ataxias in Argentina 
    Rossi, Malco Damián; Merello, Marcelo (Springer, 2025-04-08)
    Hereditary or genetic ataxias are hundreds of disorders characterized by large phenotypic, genetic, and epidemiological heterogeneity. In Argentina, 35 genetic ataxias have been identified, with SCA1 (ATX-ATXN1), SCA2 ...
  • Association of the Timing and Type of Acute Symptomatic Seizures With Poststroke Epilepsy and Mortality 
    Schubert, Kai Michael; Zieglgänsberger, Dominik; Bicciato, Giulio; Abraira, Laura; Santamarina, Estevo; Álvarez-Sabín, José; Ferreira-Atuesta, Carolina; Katan, Mira; Sinka, Lucia; Terziev, Robert; Deligas, Nico; Erdélyi-Canavese, Barbara; Felbecker, Ansgar; Siebel, Philip; Winklehner, Michael; von Oertzen, Tim J.; Wagner, Judith N.; Gigli, Gian Luigi; Nilo, Annacarmen; Alet, Matías Javier (Lippincott Williams & Wilkins, 2025-07)
    Background: Acute symptomatic seizures (ASyS) increase the risk of epilepsy and mortality after a stroke. The impact of the timing and type of ASyS remains unclear. Methods: This multicenter cohort study included data ...
  • Flow-diverting stents for the treatment of unruptured distal anterior cerebral artery aneurysms: analysis of the CRETA Registry 
    Scarcia, Luca; Clarençon, Frédéric; Dmytriw, Adam A.; Shotar, Eimad; Premat, Kevin; Jabbour, Pascal; Tjoumakaris, Stavropoula I.; Gooch, Reid; Psychogios, Marios-Nikos; Ntoulias, Nikolaos; Sporns, Peter B.; Puri, Ajit S.; Singh, Jasmeet; Kuhn, Anna Luisa; Hassan, Ameer E.; Algin, Oktay; Möhlenbruch, Markus A.; Hohenstatt, Sophia; Ferrario, Ángel; Pujol Lereis, Virginia Andrea (BMJ Publishing Group, 2025-01-27)
    Background: Data about the safety and the efficacy of flow diversion for distal anterior cerebral artery (DACA) aneurysms are limited. We present the largest multicenter analysis evaluating the outcomes of flow diversion ...
  • [Outcomes of a Transdisciplinary Rehabilitation Program for Patients with Consciousness Disorders (2006-2022, Argentina)] 
    Rivas, Marìa Elisa; Ron, Melania; Salierno, Fernando Martín; Broggi, María Soledad; Bonamico, Lucas (Universidad Nacional De Cordoba, Facultad De Ciencias Medicas, 2025-03-31)
    Introduction: After suffering brain damage with altered consciousness, clinically stable patients are referred to rehabilitation programs. The objective of this study is to describe the results of a transdisciplinary ...