Repositorio Institucional FLENI: Recent submissions

  • In Memoriam C. Warren Olanow (1941–2024) 
    Fung, Victor S.C.; Bhatia, Kailash P.; Burn, David J.; Goetz, Christopher G.; Hallett, Mark; Jankovic, Joseph; Kieburtz, Karl; Klein, Christine; Kordower, Jeffrey H.; Lang, Anthony E.; Merello, Marcelo; Stern, Matthew B.; Stoessl, A. Jon; Thompson, Philip D. (Wiley, 2025-02-13)
    Resumen no disponible
  • Risk and impact of stroke across 38 countries and territories of the Americas from 1990 to 2021: a population-based trends analysis from the Global Burden of Disease Study 2021 
    Martinez, Ramón; Muñoz-Venturelli, Paula; Ordunez, Pedro; Fregni, Felipe; Abanto, Carlos; Alet, Matías Javier; Alvarez, Tony Fabián; Amaya, Pablo; Ameriso, Sebastián Francisco; Arauz, Antonio; Barboza, Miguel A.; Bayona, Hernán; Bernabé-Ortiz, Antonio; Calleja, Juan; Cano-Nigenda, Vanessa; Carbonera, Leonardo Augusto; Carrillo-Larco, Rodrigo M.; Corredor, Angel; de Souza, Ana Cláudia; Rosales, Julieta Soledad (Elsevier, 2025-02-15)
    Background: Despite substantial declines in burden over time, stroke remains a public health threat in the Americas. This study aimed to assess the current magnitude, trends, and disparities in the estimates of stroke ...
  • Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia 
    Llibre Guerra, Jorge J.; Fernandez, M. Victoria; Joseph-Mathurin, Nelly; Bian, Shijia; Carter, Kathleen; Li, Yan; Aschenbrenner, Andrew J.; Pottier, Cyril; Sigurdson, Wendy; McDade, Eric; Gordon, Brian A.; Renton, Alan E.; Benzinger, Tammie L. S.; Ibañez, Laura; Barthelemy, Nico; Dominantly Inherited Alzheimer Network (Nature Publishing Company, 2025-02-10)
    We conducted an in-depth longitudinal study on an individual carrying the presenilin 2 p.Asn141Ile mutation, traditionally associated with dominantly inherited Alzheimer's disease (AD), who has remarkably remained asymptomatic ...
  • IAPRD new consensus classification of myoclonus 
    Latorre, Anna; van der Veen, S.; Pena, Ashley; Truong, Daniel; Erro, Roberto; Frucht, Steven; Ganos, Christos; Hallett, Mark; Perez-Duenas, Belen; Rossi, Malco Damián; Roze, Emmanuel; Vidailhet, Marie; Aj de Koning-Tijssen, Marina; Caviness, John N. (Elsevier, 2025-02-20)
    Introduction: Recent new advances in myoclonus characterization and etiology justify an update of the 40-year-old respected classification of myoclonus proposed by Marsden, Hallett, and Fahn. New advances include genetic ...
  • Experts envision a valuable role for tau-PET in clinical practiceand drug trials 
    Vermeiren, Marie R.; Calandri, Ismael Luis; van der Flier, Wiesje M.; van de Giessen, Elsmarieke; Ossenkoppele, Rik (Wiley, 2024)
    Background: Recent advancements in Alzheimer’s disease (AD) biomarker researchand AD drug trials prompt reflection on the value and appropriate use of tau-PET infuture clinical practice and trials. We therefore conducted ...
  • Development of a Multidomain Composite InterventionEngagement Score in the U.S. POINTER Trial 
    Ghadimi Nouran, Mina; Katula, Jeffrey A.; Ventrelle, Jennifer; Graef, Sarah; Garcia, Katelyn R.; Lovato, Laura; Wilmoth, Sharon; Woolard, Nancy; Leng, Xiaoyan; Calandri, Ismael Luis; Snyder, Heather M.; Bake, Laura D. (Wiley, 2024)
    Background Multidomain lifestyle interventions have shown promise to slow cognitive decline and possibly prevent dementia. However, challenges arise in analyzing and interpreting treatment response when participants vary ...
  • Multi-Component and Cognitive Skills Training in MildCognitive Impairment: Outcomes from a South American Study 
    Martín, María Eugenia; Martínez, Carlos; Worff, Iris; Belucci, María Agustina; Keller, Greta; Arruabarrena, Micaela María; Corvalàn, Nicolás; Clarens, María Florencia; Allegri, Ricardo Francisco; Crivelli, Lucía (Wiley, 2024)
    Background: Dementia represents a significant health challenge, with evidencesuggesting that it can be potentially delayed or prevented through non-pharmacological interventions. There are different types of non-pharmaco ...
  • Is FDG-PET metabolism associated with cognitive performancein long-Covid patients? 
    Hernández, Micaela Anahí; Santos Machado, Luiza; De Bastiani, Marco; Hugentobler Schlickmann, Thomas; Ferrari-Souza, João Pedro; Carello, Agostina; Helou, Belén; Crivelli, Lucía; Osa Sanz, Emilia; Bérgamo, Yanina; Vázquez, Silvia; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco; Zimmer, Eduardo R.; Calandri, Ismael Luis (Wiley, 2024)
    Background: Current evidence indicates that COVID-19 infection can lead toneurological complications that persist beyond 12 weeks of infection (long-COVID),often associated with cognitive decline. However, the underlying ...
  • Multi-modal AI screening for MCI and Alzheimer's Disease: results from an Argentine Cohort 
    Belloli, Laouen; Keller, Greta; Carello, Agostina; Gauder, Lara; Juantorena, Gustavo; Corvalan, Nicolás; Allegri, Ricardo Francisco; Crivelli, Lucía; Fernández Slezak, Diego (Wiley, 2024)
    Early detection of Mild Cognitive Impairment (MCI) is crucial for effective prevention. Traditional methods like expert judgment, clinical evaluations, and manual linguistic analyses are now complemented by Artificial ...
  • SARS-CoV-2 Impairs Osteoblast Differentiation Through Spike Glycoprotein and Cytokine Dysregulation 
    Freiberger, Rosa Nicole; López, Cynthia Alicia Marcela; Jarmoluk, Patricio; Palma, María Belén; Cevallos, Cintia; Sviercz, Franco Agustin; Grosso, Tomás Martín; García, Marcela Nilda; Quarleri, Jorge; Delpino, María Victoria (MDPI, 2025-01-22)
    Pulmonary and extrapulmonary manifestations have been reported following infection with SARS-CoV-2, the causative agent of COVID-19. The virus persists in multiple organs due to its tropism for various tissues, including ...
  • Tic Disorders Care Gaps in Spanish-Speaking Latin America 
    Medina Escobar, Alex; Munoz, Daniela; Gautreau, Sylvia; Rossi, Malco Damián; Pringsheim, Tamara (Wiley, 2025-02-22)
    Background: Primary tic disorders (TD) are common movement disorders in childhood. However, it is unclear if international guidelines are applied in Latin America. Objectives: To investigate the applicability of TD ...
  • Neurological deficit due to vasospasm after brain tumour resection: A single centre retrospective cohort 
    Maskin, Luis Patricio; Wainsztein, Néstor Adrián; Hlavnicka, Alejandro Félix; Ortega Escobar, Vladimir; Rodríguez Lucci, Federico (Elsevier, 2025-02-19)
    Background and objectives: Neurological deficit secondary to cerebral vasospasm following tumour resection is a rare yet significant complication that can lead to considerable morbidity and mortality. Pathophysiological ...
  • Mortalidad intrahospitalaria por accidente cerebrovascular en un centro urbano en Argentina 
    Echarri, María Martina; Rodríguez Lucci, Federico; Pujol Lereis, Virginia Andrea; Finkelsztein, Marina Y.; González, Claudio D.; Ameriso, Sebastián Francisco (Fundación Revista Medicina, 2025-03)
    Introducción: La mortalidad intrahospitalaria es influenciada por diversos factores. A pesar de la tendencia a la disminución de la mortalidad por accidente cerebrovascular (ACV) agudo en el hemisferio norte, los informes ...
  • Etiologies of rapidly progressive dementias: A systematic review and meta-analysis of causes in worldwide and Latin America 
    Cubas Guillen, Jonathan Fernando; Ardohain, Carolina; Berrios, Waleska; Deschle, Florencia; Dorman, Guido; Fernandez Boccazzi, Julian; Flores, Ignacio; Graviotto, Héctor Gastón; Isaac, Cristian Flavio; Rojas, Galeno; Román, Karen Daniela; Scribano Parada, Maria de la Paz; Sorbara, Marcos; Allegri, Ricardo Francisco; Calandri, Ismael Luis (IOS Press, 2025-01-31)
    Background: Rapidly progressive dementia (RPD) is a group of neurological diseases, where three etiologies are particularly relevant: neurodegenerative, prion and autoimmune encephalitis (AIE) diseases. Objective: The ...
  • Analysis of Risk Factors for Cerebrospinal Fluid Leakage in Endoscopic Endonasal Surgery for Neuroendocrine Pituitary Tumors 
    Cervio, Andrés Eduardo; Monsalve, Martin; Ruella, Mauro; Domecq, Lucila; Caffaratti, Guido (Thieme, 2025-02-07)
    Introduction: Neuroendocrine pituitary tumors (PitNET) account for ~15% of primary intracranial neoplasms. The endoscopic endonasal approach (EEA) is currently the most common surgical technique to treat this pathology. ...
  • Exploring Music-Based Interventions for Executive Functioning and Emotional Well-Being in Stroke Rehabilitation: A Scoping Review 
    Pfeiffer, Camila Floreana; Magee, Wendy L.; Fülöp, Rebecca; Nace, Travis C.; Castro, Candela; Iturri, Agustina; Franceschi, Jimena; Echauri, Gabriela; Gassull, Liliana; Russo, María Julieta (MDPI, 2024-10-27)
    Purpose: Stroke is one of the leading causes of disability with life-long implications requiring assessment and treatment of several functional domains. This review identifies the results from research into music-based ...
  • Brain metabolic subtypes in Long Covid individuals from a Brazilian cohort 
    Viana Jotz, Arthur; De Bastiani, Marco; Santos Machado, Luiza; Hugentobler Schlickmann, Thomas; Silveira, Maiele Dornelles; Senger, Joana Emilia; Vendramini Borelli, Wyllians; Ferrari‐Souza, João Pedro; Povala, Guilherme; Bornes da Silva, Ana Paula; Uglione da Ros, João Pedro; Bastos de Mello, Guilherme; Fakhri Kadan, Matheus; Radaelli, Graciane; de Paula de Paula Faria, Daniele; Martins Coutinho, Artur; Lourenco, Mychael V.; Hernández, Micaela Anahí; Calandri, Ismael Luis; Pascoal, Tharick A.; Matushita, Cristina Sebastião; Benardi Soder, Ricardo; Schumacher‐Schuh, Artur Francisco; Souza, Diogo O.; Costa da Costa, Jaderson; Guerini de Souza, Débora; Zimmer, Eduardo R. (John Wiley & Sons, 2024)
    Background: The Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is one of the biggest health concerns of the century. Long COVID is one of the major sequelae from the infection and include persistent neurological ...
  • Valoración mediante resonancia magnética del hidrops endolinfático en la enfermedad de Ménière 
    Goñi, Romina; Abraham, María Silvina; Laffue, Alfredo Hernan; Mac-Adden, María; Cejas, Claudia Patricia (Sociedad Argentina de Radiología, 2024-12-11)
    El laberinto membranoso es una estructura ubicada dentro de la cápsula ótica, que está formado por un conjunto de vesículas y conductos que contienen endolinfa y que conforman un sistema cerrado de circulación de líquido, ...
  • Long-term follow-up of patients with a first clinical demyelinating event (clinically isolated syndrome) who received cladribine tablets in CLASSIC-MS: Findings for the ORACLE-MS cohort 
    Giovannoni, Gavin; Boyko, Alexey; Correale, Jorge; Edan, Gilles; Freedman, Mark S.; Montalban, Xavier; Rammohan, Kottil; Stefoski, Dusan; Yamout, Bassem; Leist, Thomas; Aydemir, Aida; Borsi, Laszlo; di Cantogno, Elisabetta Verdun (SAGE, 2024-12-17)
    Background: CLASSIC-MS explored long-term outcomes of patients treated with cladribine tablets. Objective: Assess long-term efficacy in patients previously enrolled in ORACLE-MS, a Phase III parent trial. Methods: ...
  • The pleomorphic phenotype of neurosarcoidosis 
    Garat, Oscar E.; Perez Arana, Carolina I.; Perandones, Carlos E.; Correale, Jorge; Marrodán, Mariano (Springer-Verlag Italia, 2024-12-20)

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