• Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: A 1-Year Follow-up 

  Nguyen, Thanh N.; Qureshi, Muhammad M.; Klein, Piers; Yamagami, Hiroshi; Mikulik, Robert; Czlonkowska, Anna; Abdalkader, Mohamad; Sedova, Petra; Sathya, Anvitha; Lo, Hannah C.; Yassin Mansour, Ossama; Vanguru, Husitha Reddy; Lesaine, Emilie; Tsivgoulis, Georgios; Loochtan, Aaron I.; Demeestere, Jelle; Uchino, Ken; Inoa, Violiza; Goyal, Nitin; Pujol Lereis, Virginia Andrea (Lippincott Williams & Wilkins, 2023-01-24)

  Background and objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term ...
• Motor assessment of patients with multiple system atrophy: underuse of the Unified Multiple System Atrophy Rating Scale (UMSARS) 

  Ferreirós, Alexandra; Sergio Andrés, Castillo-Torres; Merello, Marcelo (Steinkopff, 2023-03-27)

  Purpose: Despite the availability of the Unified Multiple System Atrophy (MSA) Rating Scale (UMSARS) for almost two decades, studies still use scales developed for Parkinson's disease (PD) or ataxia (ATX). Our aim was to ...
• Are highly active and aggressive multiple sclerosis the same entity? 

  Correale, Jorge; Rush, Carolina A.; Barboza, Andrés (Frontiers Research Foundation, 2023-03-03)

  Resumen no disponible.
• Editors Note: Looking Forward, Looking Back 

  Merello, Marcelo; Bhatia, Kailash (Wiley, 2022-12-09)
• Incidence and case-fatality rate of stroke in General Villegas, Buenos Aires, Argentina. The EstEPA population study 

  Ameriso, Sebastián Francisco; Alet, Matías Javier; Rosales, Julieta; Rodriguez Pérez, María Soledad; Povedano, Guillermo Pablo; Pujol Lereis, Virginia Andrea; Rodríguez-Lucci, Federico; Dossi, Daiana Elizabeth; González, Claudio D.; Melcon, Mario O. (Saunders, 2023-03-20)

  Objectives: Stroke epidemiology varies among different populations. The burden of stroke is high in low- and middle-income countries. Reliable population data is needed to assess the impact of stroke and to develop policies ...
• Disease activity after discontinuation of disease-modifying therapies in patients with multiple sclerosis in Argentina: data from the nationwide registry RelevarEM 

  Zanga, Gisela; Portinari, Carla; Barber, Josefina; Ibañez, Tomas; Brolese, Lucía; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Deri, Norma; Tkachuk, Verónica; Vrech, Carlos; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Ysrraelit, María Célica; Marrodan, Mariano; Gaitán, María Inés; Correale, Jorge; RELEVAREM Study Group (Taylor & Francis, 2022-10-02)

  Introduction: The discontinuation of disease-modifying therapies (DMTs) in multiple sclerosis (MS) is commonly seen in real-world settings due to several factors. Area cover: The aim of this study is to describe the ...
• Systemic Ghrelin Treatment Induces Rapid, Transient, and Asymmetric Changes in the Metabolic Activity of the Mouse Brain 

  De Francesco, Pablo Nicolás; Fernández, Gimena; Uriarte, Maia; Urrutia, Leandro; Ponce de León, Magdalena; Fehrentz, Jean-Alain; Falasco, Germán; Perello, Mario (Karger, 2022-07-29)

  Introduction: Ghrelin regulates a variety of functions by acting in the brain. The targets of ghrelin in the mouse brain have been mainly mapped using immunolabeling against c-Fos, a transcription factor used as a marker ...
• Abstract WMP9: Favorable Mechanical Thrombectomy Outcomes From The Latin American Stroke Registry (lase) And Resilient Trial Compared To A 90-day Functional And Mortality Predictive Model 

  Torrealba-Acosta, Gabriel; Barboza, Miguel A.; Arauz, Antonio; Amaya, Pablo F.; Ameriso, Sebastian Francisco; Cano, Vanessa; Flores, Alan F.; Lavados, Pablo M.; Pujol Lereis, Virginia Andrea; Serrano, Fabiola; Kent, Thomas A .; Mandava, Pitchaiah (Lippincott Williams & Wilkins, 2023-02-02)

  Introduction: Except for RESILIENT, there is a paucity of randomized controlled trials (RCTs) for stroke from Latin America (LA), home to growing stroke burden. Comparison between stroke population typically suffers from ...
• Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus 

  Čarna, Maria; Onyango, Isaac G.; Katina, Stanislav; Holub, Dušan; Novotny, Jan Sebastian; Nezvedova, Marketa; Jha, Durga; Nedelska, Zuzana; Lacovich, Valentina; Vande Vyvere, Thijs; Houbrechts, Ruben; Garcia-Mansfield, Krystine; Sharma, Ritin; David-Dirgo, Victoria; Vyhnalek, Martin; Texlova, Kateřina; Chaves, Hernán; Bakkar, Nadine; Pertierra, Lucia; Sevlever, Gustavo Emilio (Wiley, 2023-02-24)

  The choroid plexus (ChP) produces and is bathed in the cerebrospinal fluid (CSF), which in aging and Alzheimer's disease (AD) shows extensive proteomic alterations including evidence of inflammation. Considering inflammation ...
• Abstract WP14: A Patient-level Data Euclidean-matched Analysis Of Reperfusion Therapies In Acute Ischemic Stroke From The Latin American Stroke Registry (lase) 

  Barboza, Miguel A.; Torrealba-Acosta, Gabriel; Valdez, Hector; Arauz, Antonio; Abanto, Carlos; Amaya, Pablo F.; Ameriso, Sebastian Francisco; Bonardo, Pablo; Cano, Vanessa; Diaz-Escobar, Luis; Ecos, Rosa Lizbeth; Fernández Morales, Huberth; Gómez-Schneider, Maia; Gongora - Rivera, Fernando F.; Huamani, Charles; Lavados, Pablo M.; Marquez-Romero, Juan M.; Martins, Sheila; Navia Gonzalez, Victor Hugo; Pujol Lereis, Virginia Andrea (Lippincott Williams & Wilkins, 2023-02-02)

  Introduction: As acute stroke therapies expand to less well-resourced regions, it is imperative to study real-world data to assess outcomes and the quality of stroke care. The present study analyzes clinical, and imaging ...
• Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease 

  Xiong, Chengjie; McCue, Lena M.; Buckles, Virginia; Grant, Elizabeth; Agboola, Folasade; Coble, Dean; Bateman, Randall J.; Fagan, Anne M.; Benzinger, Tammie L. S.; Hassenstab, Jason; Schindler, Suzanne E.; McDade, Eric; Moulder, Krista; Gordon, Brian A.; Cruchaga, Carlos; Day, Gregory S.; Ikeuchi, Takeshi; Suzuki, Kazushi; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (DIAN) (Wiley, 2023-01-14)

  Background: Comparisons of late-onset Alzheimer's disease (LOAD) and autosomal dominant AD (ADAD) are confounded by age. Methods: We compared biomarkers from cerebrospinal fluid (CSF), magnetic resonance imaging, and ...
• Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort 

  Vollstedt, Eva-Juliane; Schaake, Susen; Lohmann, Katja; Padmanabhan, Shalini; Brice, Alexis; Lesage, Suzanne; Tesson, Christelle; Vidailhet, Marie; Wurster, Isabel; Hentati, Faycel; Mirelman, Anat; Giladi, Nir; Marder, Karen; Waters, Cheryl; Fahn, Stanley; Kasten, Meike; Brüggemann, Norbert; Rossi, Malco; Merello, Marcelo; MJFF Global Genetic Parkinson's Disease Study Group (Wiley, 2023-01-24)

  Background: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of ...
• LatAm Fingers Initiative: Bringing Diversity Upfront 

  Crivelli, Lucía (The Alzheimer's Association, 2022-12)
• Life events and the onset of motor symptoms in Parkinson's disease 

  Paez-Maggio, Mauricio; Rossi, Malco; Martinez, V.; Wainberg, Florencia N.; Merello, Marcelo (Elsevier, 2023-01-11)

  Background: Whether there may be any relationship between stressful or traumatic life events (LE) and the subsequent motor symptoms onset in Parkinson's disease (PD) is still controversial. Objectives: To explore whether ...
• Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study 

  Millar, Peter R.; Gordon, Brian A.; Luckett, Patrick H.; Benzinger, Tammie L. S.; Cruchaga, Carlos; Fagan, Anne M.; Hassenstab, Jason J.; Perrin, Richard J.; Schindler, Suzanne E.; Allegri, Ricardo Francisco; Day, Gregory S.; Farlow, Martin R.; Mori, Hiroshi; Nübling, Georg; Dominantly Inherited Alzheimer Network; Bateman, Randall J.; Morris, John C.; Ances, Beau M. (eLife Sciences Publications, 2023-01-06)

  Background: Estimates of 'brain-predicted age' quantify apparent brain age compared to normative trajectories of neuroimaging features. The brain age gap (BAG) between predicted and chronological age is elevated in symptomatic ...
• LatAm Fingers Initiative: Challenges and opportunities of launching amulticultural trial in pandemic times 

  Calandri, Ismael Luis; Crivelli, Lucía; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sosa Ortiz, Ana Luisa; Salinas-Contreras, Rosa María; Suemoto, Claudia Kimie; Velilla, Lina M.; Sanches Yassuda, Mónica; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco; LatAm FINGERS initiative (The Alzheimer's Association, 2022-12-20)
• LatAm FINGERS:Overcoming Barriers for a Dementia Prevention Trial Startup 

  Calandri, Ismael Luis; Crivelli, Lucía; Caramelli, Paulo; Lopera, Francisco; Nitrini, Ricardo; Sosa Ortiz, Ana Luisa; Salinas-Contreras, Rosa María; Suemoto, Claudia Kimie; Velilla, Lina M.; Sanches Yassuda, Mónica; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco; LatAm FINGERS initiative (The Alzheimer's Association, 2022)
• Comparison of amyloid accumulation between Down syndrome and autosomal-dominant Alzheimer disease 

  Boerwinkle, Anna H.; Gordon, Brian A.; Wisch, Julie K.; Flores, Shaney; Rachel L. Henson, Rachel L.; Butt, Omar Hameed; Chen, Charles D.; Benzinger, Tammie L.S.; Fagan, Anne M.; Handen, Benjamin L; Christian, Bradley T.; Head, Elizabeth; Mapstone, Mark; Klunk, William E.; Rafii, Michael S.; O’Bryant, Sid E.; Price, Julie C.; Schupf, Nicole; Allegri, Ricardo Francisco; the Alzheimer’s Biomarker Consortium-Down Syndrome and the Dominantly Inherited Alzheimer Network (The Alzheimer’s Association, 2022)
• Shared decision making in the treatment of multiple sclerosis: A consensus based on Delphi methodology 

  Alonso, Ricardo; Carnero Contentti, Edgar; Graña, Marcos; Linares, Ramiro; López, Pablo; Mainella, Carolina; Marrodán, Mariano; Miguez, Jimena; Pagani Cassará, Fátima; Tavolini, Darío; Batagelj, Sebastián (Elsevier, 2022-12-09)

  Shared decision making is a way of incorporating patients' preferences and values into the decisions regarding the treatment and follow-up plan for the condition that affects them. It is currently applied mainly in the ...
• Teleneuropsychological assessment in South America: A perspective from patients and neuropsychologists 

  Arruabarrena, Micaela María; Martin, María Eugenia; Calandri, Ismael Luis; Corvalán, Nicolás; Helou, María Belén; Martínez, Carlos; Crivelli, Lucía (Universidad de la Costa, 2022-12-23)

  Teleneuropsychology (teleNP) in Argentina was promoted by the COVID-19 pandemic. This investigation aimed to evaluate patients’ and neuropsychologists’ satisfaction with teleNP and to identify the advantages and disadvantages ...

View more