Background and objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term ...
Purpose: Despite the availability of the Unified Multiple System Atrophy (MSA) Rating Scale (UMSARS) for almost two decades, studies still use scales developed for Parkinson's disease (PD) or ataxia (ATX). Our aim was to ...
Objectives: Stroke epidemiology varies among different populations. The burden of stroke is high in low- and middle-income countries. Reliable population data is needed to assess the impact of stroke and to develop policies ...
Introduction: The discontinuation of disease-modifying therapies (DMTs) in multiple sclerosis (MS) is commonly seen in real-world settings due to several factors.
Area cover: The aim of this study is to describe the ...
De Francesco, Pablo Nicolás; Fernández, Gimena; Uriarte, Maia; Urrutia, Leandro; Ponce de León, Magdalena; Fehrentz, Jean-Alain; Falasco, Germán; Perello, Mario(Karger, 2022-07-29)
Introduction: Ghrelin regulates a variety of functions by acting in the brain. The targets of ghrelin in the mouse brain have been mainly mapped using immunolabeling against c-Fos, a transcription factor used as a marker ...
Torrealba-Acosta, Gabriel; Barboza, Miguel A.; Arauz, Antonio; Amaya, Pablo F.; Ameriso, Sebastian Francisco; Cano, Vanessa; Flores, Alan F.; Lavados, Pablo M.; Pujol Lereis, Virginia Andrea; Serrano, Fabiola; Kent, Thomas A .; Mandava, Pitchaiah(Lippincott Williams & Wilkins, 2023-02-02)
Introduction: Except for RESILIENT, there is a paucity of randomized controlled trials (RCTs) for stroke from Latin America (LA), home to growing stroke burden. Comparison between stroke population typically suffers from ...
The choroid plexus (ChP) produces and is bathed in the cerebrospinal fluid (CSF), which in aging and Alzheimer's disease (AD) shows extensive proteomic alterations including evidence of inflammation. Considering inflammation ...
Barboza, Miguel A.; Torrealba-Acosta, Gabriel; Valdez, Hector; Arauz, Antonio; Abanto, Carlos; Amaya, Pablo F.; Ameriso, Sebastian Francisco; Bonardo, Pablo; Cano, Vanessa; Diaz-Escobar, Luis; Ecos, Rosa Lizbeth; Fernández Morales, Huberth; Gómez-Schneider, Maia; Gongora - Rivera, Fernando F.; Huamani, Charles; Lavados, Pablo M.; Marquez-Romero, Juan M.; Martins, Sheila; Navia Gonzalez, Victor Hugo; Pujol Lereis, Virginia Andrea(Lippincott Williams & Wilkins, 2023-02-02)
Introduction: As acute stroke therapies expand to less well-resourced regions, it is imperative to study real-world data to assess outcomes and the quality of stroke care. The present study analyzes clinical, and imaging ...
Xiong, Chengjie; McCue, Lena M.; Buckles, Virginia; Grant, Elizabeth; Agboola, Folasade; Coble, Dean; Bateman, Randall J.; Fagan, Anne M.; Benzinger, Tammie L. S.; Hassenstab, Jason; Schindler, Suzanne E.; McDade, Eric; Moulder, Krista; Gordon, Brian A.; Cruchaga, Carlos; Day, Gregory S.; Ikeuchi, Takeshi; Suzuki, Kazushi; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (DIAN)(Wiley, 2023-01-14)
Background: Comparisons of late-onset Alzheimer's disease (LOAD) and autosomal dominant AD (ADAD) are confounded by age.
Methods: We compared biomarkers from cerebrospinal fluid (CSF), magnetic resonance imaging, and ...
Background: As gene-targeted therapies are increasingly being developed for Parkinson's disease (PD), identifying and characterizing carriers of specific genetic pathogenic variants is imperative. Only a small fraction of ...
Background: Whether there may be any relationship between stressful or traumatic life events (LE) and the subsequent motor symptoms onset in Parkinson's disease (PD) is still controversial.
Objectives: To explore whether ...
Millar, Peter R.; Gordon, Brian A.; Luckett, Patrick H.; Benzinger, Tammie L. S.; Cruchaga, Carlos; Fagan, Anne M.; Hassenstab, Jason J.; Perrin, Richard J.; Schindler, Suzanne E.; Allegri, Ricardo Francisco; Day, Gregory S.; Farlow, Martin R.; Mori, Hiroshi; Nübling, Georg; Dominantly Inherited Alzheimer Network; Bateman, Randall J.; Morris, John C.; Ances, Beau M.(eLife Sciences Publications, 2023-01-06)
Background: Estimates of 'brain-predicted age' quantify apparent brain age compared to normative trajectories of neuroimaging features. The brain age gap (BAG) between predicted and chronological age is elevated in symptomatic ...
Shared decision making is a way of incorporating patients' preferences and values into the decisions regarding the treatment and follow-up plan for the condition that affects them. It is currently applied mainly in the ...
Arruabarrena, Micaela María; Martin, María Eugenia; Calandri, Ismael Luis; Corvalán, Nicolás; Helou, María Belén; Martínez, Carlos; Crivelli, Lucía(Universidad de la Costa, 2022-12-23)
Teleneuropsychology (teleNP) in Argentina was promoted by the COVID-19 pandemic. This investigation aimed to evaluate patients’ and neuropsychologists’ satisfaction with teleNP and to identify the advantages and disadvantages ...