Background: Alzheimer's disease postmortem studies demonstrate that amyloid plaques and neurofibrillary tangles are present in subcortical regions.
Objective: To investigate longitudinal subcortical structural changes in ...
BackgroundAlthough levodopa is the gold standard treatment for Parkinson's disease (PD), its chronic use is associated with levodopa-induced dyskinesia (LID), a motor complication that impacts prognosis, quality of life, ...
Introduction: Despite less education being common in Latin America, there is no systematic review on the use of brief cognitive screening (BCS) tools in illiterate and low-educated adults in the region. We systematically ...
Magnetic resonance imaging (MRI) plays a central role in the diagnosis, differential diagnosis, and monitoring of neuroimmunological disorders, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder ...
Purpose of review: As the life expectancy of people with multiple sclerosis (PwMS) increases, the importance of recognizing and addressing specific needs and challenges faced by those undergoing age-related sex hormone ...
Bagnati, Pablo M.; Allegri, Ricardo Francisco; Demey, Ignacio; Bártoli, Gastón; Bérgamo, Yanina; Campos, Jorge; Castro, Diego M.; Chrem Méndez, Patricio Alexis; Cristalli, Diana Olga; Fernández, María Cecilia; Fernández, María Laura; García Lombardi, Juan Pablo; Kremer, Janus; Magrath Guimet, Nahuel; Ollari, Juan; Osa Sanz, Emilia; Russo, María Julieta; Surace, Ezequiel Ignacio; Vázquez, Silvia; Waisman Campos, Marcela(Vertex, 2026-01-10)
El Consenso Argentino para el diagnóstico de las demencias es una iniciativa de la Asociación Argentina de Psiquiatría Biológica (AAPB). Este documento tuvo como objetivo principal elaborar un instrumento eficiente para ...
Alessandra, Dodich; Andrea, Panzavolta; Giulia, Funghi; Claudia, Meli; Cristina, Festari; Thanos, Chatzikostopoulos; Christian, Chicherio; Clarens, María Florencia; Fabricio, Ferreira de Oliveira; Marco, Filardi; Agustin, Ibanez; Laura, Invernizzi; Thibaud, Lebouvier; Giancarlo, Logroscino; Sarah E., MacPherson; Riccardo, Manca; Camillo, Marra; Jordi A., Matias-Guiu; SIGNATURE Consortium(BioMed Central Ltd., 2025-12-06)
Background: Socio-cognitive assessment in neurocognitive disorders (NCDs) is rare in clinical practice and no consensus exists as to a uniform operationalization of socio-cognitive measures for NCDs in memory clinics. The ...
Purpose: To evaluate the clinical effectiveness and safety of genicular artery embolization (GAE) for managing chronic knee pain after total knee arthroplasty (TKA) in a retrospective multicenter study.
Materials and ...
Objective
Glucose transporter type 1 deficiency syndrome (Glut1DS) is a rare metabolic encephalopathy caused by pathogenic SLC2A1 variants. Ketogenic dietary therapy (KDT) is the mainstay of treatment. In Latin America, ...
Arias-Tello, Piero A.; Coronado-Caceres, Carlos F.; Serrano-Sablich, Mario E.; Mantilla, Guillemo; Goicochea, María Teresa; Alarcon-Ruiz, Christoper A.(BioMed Central, 2026-02-07)
BACKGROUND: Medication-overuse headache (MOH) is a disabling condition, particularly in settings with limited access to advanced preventive therapies. Peripheral nerve blocks (PNB) may offer a pragmatic option to reduce ...
Objetivo
El deterioro neurológico temprano (DNT) en infartos lacunares constituye una complicación frecuente, especialmente durante los primeros días de hospitalización, y aún carece de un abordaje terapéutico estandarizado. ...
Background: Neurological sequelae from acute meningitis are estimated to affect more than 30% of survivors worldwide, though often underreported or undetected due to inadequate follow-up, limited access to healthcare ...
Dementia prevalence is increasing with aging worldwide, a leading cause of disability in Latin American Countries (LAC). Interestingly, physical performance has been reported as a predictor of cognitive decline, and gait ...
Background Acute community-acquired bacterial meningitis remains a significant global health concern with significant mortality and morbidity, including neurological sequelae such as sensorineural hearing loss (SNHL). Early ...
Alet, Matías Javier; Melcon, Mario O.; Ameriso, Sebastián Francisco(Fundación Revista Medicina, 2026-01)
Introducción: Existen pocos estudios poblacionales recientes sobre mortalidad en Argentina, fuera del contexto de la pandemia por COVID-19. Nuestro objetivo fue describir la mortalidad general y por causas en el partido ...
Sharma, Mukul; Dong, Qiang; Hirano, Teruyuki; Kasner, Scott E.; Saver, Jeffrey; Masjuan, Jaime; Demchuk, Andrew M.; Cordonnier, Charlotte; Bereczki, Daniel; Tsivgoulis, Georgios; Veltkamp, Roland; Staikov, Ivan; Bae, Hee-Joon; Campbell, Bruce C. V.; Zini, Andrea; Lee, I-Hui; Ameriso, Sebastián Francisco; Kovar, Martin; Mikulik, Robert; Lemmens, Robin(Oxford, 2026-01-01)
Introduction: Genetic deficiency of factor XI is associated with a reduced risk of ischemic stroke. Asundexian is a direct inhibitor of activated factor XIa (FXIa) with a low risk of bleeding in early trials. We seek to ...
Oligodendrocytes, traditionally recognized for their role in axonal myelination, are increasingly appreciated as metabolically dynamic and functionally diverse cells integral to central nervous system (CNS) homeostasis. ...
Background: Episodic neurologic disorders, such as paroxysmal torticollis, paroxysmal tonic upward gaze deviation, migraine, and episodic ataxia, represent a diagnostic challenge in paediatric patients. Variants in the ...