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Enfermedades Desmielinizantes

Enfermedades Desmielinizantes

Recent Submissions

  • Pérez, María Julia; Carden, Tomás Roberto; Dos Santos Claro, Paula Ayelen; Silberstein, Susana; Páez, Pablo Martin; Cheli, Veronica Teresita; Correale, Jorge; Pasquini, Juana María (Sage, 2023-04-24)
    Although transferrin (Tf) is a glycoprotein best known for its role in iron delivery, iron-independent functions have also been reported. Here, we assessed apoTf (aTf) treatment effects on Neuro-2a (N2a) cells, a mouse ...
  • Zarate, María Agustina; Marrodán, Mariano; Piedrabuena, María Agustina; Fiol, Marcela Paula; Ysrraelit, María Célica; Correale, Jorge (American Academy of Neurology, 2024-04-09)
    Objective: To analyze characteristics of patients with secondary progressive Multiple Sclerosis (SPMS) exhibiting Progression Independent of Relapse Activity (PIRA) and to identify factors contributing to earlier ...
  • Piedrabuena, María Agustina; Correale, Jorge; Fiol, Marcela Paula; Marrodán, Mariano; Ysrraelit, María Célica (Elsevier, 2024-05-16)
    Background: Knowledge of the safety and efficacy of disease-modifying therapies (DMTs) in older patients with Multiple Sclerosis (pwMS) is limited due to their exclusion from clinical trials. Our purpose is to evaluate the ...
  • Pestchanker, Claudia; Bertado Cortez, Brenda; Lana Peixoto, Marco A.; Gortari, José Ignacio; Castro Suarez, Sheila; Caparo Zamalloa, César; Galiana, Graciana; Peñalver, Francisco; Daccach Marques, Vanesa; Messias, Katharina; Galleguillos, Lorna; García, Fernando; Rojas, Juan I.; Patrucco, Liliana; Cristiano, Edgardo; Tkachuk, Verónica; Liwacki, Susana; Correale, Jorge; Marrodan, Mariano; Ysraelit, María Célica; Vrech, Carlos; Deri, Norma; Leguizamon, Felisa; Tavolini, Darío; Mainella, Carolina; Zanga, Gisela; Alonso Serena, Marina; Ciampi, Ethel; Herval Ribeiro Soares Neto, Herval; López, Pablo; Carnero Contentti, Edgar (Springer-Verlag, 2024-03-17)
    Introduction: We aimed to assess the frequency, duration, and severity of area postrema syndrome (APS) during follow-up in neuromyelitis optica spectrum disorder (NMOSD) patients, as well as its association with inflammatory ...
  • Bar-Or, Amit; Wiendl, Heinz; De Seze, Jerome; Correale, Jorge; Cross, Anne; Derfuss, Tobias; Selmaj, Krzysztof; Winthrop, Kevin; Giacomini, Paul; Sacca, Francesco; Hu, Xixi; Sullivan, Roseanne; Jehl, Valentine; Boer, Ibolya; Bhatt, Alit; Hauser, Stephen (American Academy of Neurology, 2024-03-09)
  • Rojas, J.I.; Gracía, F.; Parciak, T.; Alonso, R.; Becker, J.; Treviño Frenk, I.; Alonso Serena, M.; Giunta, D.; Abad, P.; Carnero Contentti, Edgar; Carrá, A.; Correa Díaz, E.P.; Correale, Jorge; Cristiano, E.; Flores, J.; Fruns, M.; Galleguillos, L.; Garcea, O.; Hamuy, F.; Lana Peixoto, M.; Navas, C.; Pappais Alvarenga, R.; Patrucco, L.; Rivera, V.; Tenembaum, S.; Ysrraelit, María Célica; Peeters, L.M. (Viguera, 2024-04-01)
    Introduction: The primary objective of the core data set is to reduce heterogeneity and promote harmonization among data sources in EM, thereby reducing the time needed to execute real life data collection efforts. Recently, ...
  • Barboza, Andrés G.; Sinay, Vladimiro; Alonso, Ricardo; Carnero Contentti, Edgar; Hryb, Javier; Silva, Berenice Anabel; Tavolini, Darío; Ysrraelit, María Célica; Correale, Jorge (Revista de Neurología, 2024-03-16)
    Los estudios clínicos de tratamientos para personas con esclerosis múltiple (pEM) se realizan en poblaciones seleccionadas, que excluyen a pacientes que presenten comorbilidades o medicaciones concomitantes. Sin embargo, ...
  • Mattera, Vanesa S.; Occhiuzzi, Federico; Correale, Jorge; Pasquini, Juana María (Wiley, 2023-10-20)
    Extracellular vesicles (EVs) are involved in diverse cellular functions, playing a significant role in cell-to-cell communication in both physiological conditions and pathological scenarios. Therefore, EVs represent a ...
  • Carnero Contentti, Edgar; López, Pablo A.; Pettinicchi, Juan Pablo; Criniti, Juan; Pappolla, Agustín; Miguez, Jimena; Cristiano, Edgardo; Patrucco, Liliana; Liwacki, Susana; Tkachuk, Verónica; Balbuena, María E.; Vrech, Carlos; Deri, Norma; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Leguizamon, Felisa; Luetic, Geraldine; Menichini, María L.; Tavolini, Darío (Sage, 2023-10-17)
    We aimed to evaluate mortality and causes of death among Argentinean neuromyelitis optica spectrum disorder (NMOSD) patients and identify predictors of death. Retrospective study included 158 NMOSD patients and 11 (7%) ...
  • Giovannoni, Gavin; Boyko, Alexey; Correale, Jorge; Edan, Gilles; Freedman, Mark S.; Montalban, Xavier; Rammohan, Kottil; Stefoski, Dusan; Yamout, Bassem; Leist, Thomas; Aydemir, Aida; Borsi, Laszlo; Verdun di Cantogno, Elisabetta (Future Medicine, 2023-08-03)
    What is this summary about?: Previous studies have shown that people living with multiple sclerosis (MS) treated with cladribine tablets have fewer relapses (where new symptoms occur or existing symptoms get worse for 24 ...
  • Wies Mancini, Victoria Sofía Berenice; Mattera, Vanesa S.; Pasquini, Juana María; Pasquini, Laura Andrea; Correale, Jorge (Wiley on behalf of the International Society for Neurochemistry, 2023-12-06)
    Microglia (MG) play a crucial role as the predominant myeloid cells in the central nervous system and are commonly activated in multiple sclerosis. They perform essential functions under normal conditions, such as actively ...
  • Carnero Contentti, Edgar; López, Pablo A.; Pappolla, Agustín; Alonso, Ricardo; Silva, Berenice Anabel; Deri, Norma; Balbuena Aguirre, María Eugenia; Burgos, Marcos; Luetic, Geraldine G.; Alvez Pinheiro, Amelia; Cabrera, Mariela; Hryb, Javier; Nofal, Pedro; Pestchanker, Claudia; Vrech, Carlos; Tavolini, Darío; Marrodan, Mariano; Ysrraelit, María Célica; Correale, Jorge; on behalf RelevarEM (Springer-Verlag Italia, 2023-12-30)
    We aimed to evaluate the incidence of SARS-CoV-2 breakthrough infection of SARS-CoV-2 vaccines in people with MS (PwMS) on high-efficacy disease-modifying therapies (HET) included in the national MS registry in Argentina ...
  • Shirzadi, Zahra; Schultz, Stephanie A.; Yau, Wai-Ying W.; Joseph-Mathurin, Nelly; Fitzpatrick, Colleen D.; Levin, Raina; Kantarci, Kejal; Preboske, Gregory M.; Jack Jr, Clifford R.; Farlow, Martin R.; Hassenstab, Jason; Jucker, Mathias; Morris, John C.; Xiong, Chengjie; Karch, Celeste M.; Levey, Allan I.; Gordon, Brian A.; Schofield, Peter R.; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network and the Alzheimer’s Disease Neuroimaging Initiative (American Medical Association, 2023-12-01)
    Importance: Increased white matter hyperintensity (WMH) volume is a common magnetic resonance imaging (MRI) finding in both autosomal dominant Alzheimer disease (ADAD) and late-onset Alzheimer disease (LOAD), but it remains ...
  • Deri, Norma; Barboza, Andrés G.; Vrech, Carlos; Rey, Roberto; Burgos, Marcos; Fiol, Marcela Paula; Calvo Vildoso, Christian; Patrucco, Liliana; José, Gustavo; Aliberti, Paula; Chirico, Daniela; Federico, María B.; Seifer, Gustavo; Piedrabuena, Raúl (Elsevier, 2023-12-31)
    Background: Most Multiple Sclerosis (MS) clinical trials fail to assess the long-term effects of disease-modifying therapies (DMT) or disability. Methods: COLuMbus was a single-visit, cross-sectional study in Argentina ...
  • Carnero Contentti, Edgar; Lopez, Pablo A.; Tkachuk, Verónica; Vrech, Carlos; Zarate, María A.; Correale, Jorge; Deri, Norma; Luetic, Geraldine; Marrodán, Mariano; Pagani Cassara, Fátima; Tavolini, Darío; Ysrraelit, María Célica; Balbuena, María E.; Hryb, Javier; Chiganer, Edson; Leguizamon, Felisa; Knorre, Eduardo; Zanga, Gisela; Pestchanker, Claudia; Barboza, Andrés (Sage, 2023-07-25)
    Background: We aimed to assess the frequency of new asymptomatic lesions on brain and spinal imaging (magnetic resonance imaging (MRI)) and their association with subsequent relapses in a large cohort of neuromyelitis ...
  • Solomon, Andrew J.; Arrambide, Georgina; Brownlee, Wallace J.; Flanagan, Eoin P.; Amato, Maria Pia; Amezcua, Lilyana; Banwell, Brenda L.; Barkhof, Frederik; Corboy, John R.; Correale, Jorge; Fujihara, Kazuo; Graves, Jennifer; Harnegie, Mary Pat; Hemmer, Bernhard; Lechner-Scott, Jeannette; Marrie, Ruth Ann; Newsome, Scott D.; Rocca, Maria A.; Royal, Walter; Waubant, Emmanuelle L. (Lancet, 2023-07-19)
    Accurate diagnosis of multiple sclerosis requires careful attention to its differential diagnosis-many disorders can mimic the clinical manifestations and paraclinical findings of this disease. A collaborative effort, ...
  • Solomon, Andrew J.; Marrie, Ruth Ann; Viswanathan, Shanthi; Correale, Jorge; Magyari, Melinda; Robertson, Neil P.; Saylor, Deanna R.; Kaye, Wendy; Rechtman, Lindsay; Bae, Eunchan; Shinohara, Russell; King, Rachel; Laurson-Doube, Joanna; Helme, Anne (Lippincott Williams & Wilkins, 2023-06-15)
    Background and objectives: Recent data suggest increasing global prevalence of multiple sclerosis (MS). Early diagnosis of MS reduces the burden of disability-adjusted life years and associated health care costs. Yet ...
  • Silva, Berenice A.; Carnero Contentti, Edgar; Becker, Jefferson; Carranza, José I.; Correa-Díaz, Patricio E.; Galleguillos Goiry, Lorna; Garcea, Orlando; Gracia, Fernando; Hamuy, Fernando; Macías, Miguel Angel; Navas, Carlos; Nuñez, Sebastián; Rojas, Juan Ignacio; Farez, Mauricio Franco; Alonso, Ricardo; López, Pablo (Elsevier, 2023-06-20)
    Introduction: The emergence of several therapeutic options in multiple sclerosis (MS), which significantly modify the immune system functioning, has led to the need for the consideration of additional factors, such as risk ...
  • Rojas, Juan Ignacio; Alonso, Ricardo; Cabrera, Mariela; Carnero Contentti, Edgar; Cristiano, Edgardo; Deri, Norma; Hryb, Javier; Lopez, Pablo; Luetic, Geraldine; Patrucco, Liliana; Tkachuk, Veronica; Ysrraelit, María Célica; Zanga, Gisela; Cruces, Leonel; Turk, Gabriela; Longueira, Yesica; Laufer, Natalia; Nuñez, Sebastián (Fundación Revista Medicina, 2023-03-02)
    Introduction: The objective was to assess the immunogenicity and effectiveness of vaccines against SARSCoV-2 in multiple sclerosis (MS) patients included in the Argentinean MS registry. Methods: A prospective cohort ...
  • Plantone, Domenico; Sabatelli, Eleonora; Locci, Sara; Marrodán, Mariano; Laakso, Sini M.; Mateen, Farrah J.; Feresiadou, Amalia; Buelens, Tom; Bianco, Assunta; Fiol, Marcela Paula; Correale, Jorge; Tienari, Pentti; Calabresi, Paolo; De Stefano, Nicola; Iorio, Raffaele (Wiley, 2023-06-19)
    Background and purpose: Serum levels of neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are promising neuro-axonal damage and astrocytic activation biomarkers. Susac syndrome (SS) is an ...

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