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Listar Enfermedades Desmielinizantes por título

Listar Enfermedades Desmielinizantes por título

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  • 2-Chlorodeoxyadenosine (Cladribine) preferentially inhibits the biological activity of microglial cells 
    Aybar, Florencia; Pérez, María Julia; Marcora, María Silvina; Samman, María Eugenia; Marrodán, Mariano; Pasquini, Juana María; Correale, Jorge (Elsevier Science, 2022-01-29)
    Cladribine (2CdA) is a synthetic chlorinated purine nucleoside analogue which acts as a pro-drug requiring intracellular phosphorylation to be activated. It is biologically active in selected cell types, which results in ...
  • A Comprehensive Assessment of Progression Independent of Relapse Activity in a Cohort of Patients with Secondary Progressive Multiple Sclerosis (P8-6.010) 
    Zarate, María Agustina; Marrodán, Mariano; Piedrabuena, María Agustina; Fiol, Marcela Paula; Ysrraelit, María Célica; Correale, Jorge (American Academy of Neurology, 2024-04-09)
    Objective: To analyze characteristics of patients with secondary progressive Multiple Sclerosis (SPMS) exhibiting Progression Independent of Relapse Activity (PIRA) and to identify factors contributing to earlier ...
  • A plain language summary on assessing the long-term effectiveness of cladribine tablets in people living with relapsing multiple sclerosis: The CLASSIC-MS study 
    Giovannoni, Gavin; Boyko, Alexey; Correale, Jorge; Edan, Gilles; Freedman, Mark S.; Montalban, Xavier; Rammohan, Kottil; Stefoski, Dusan; Yamout, Bassem; Leist, Thomas; Aydemir, Aida; Borsi, Laszlo; Verdun di Cantogno, Elisabetta (Future Medicine, 2023-08-03)
    What is this summary about?: Previous studies have shown that people living with multiple sclerosis (MS) treated with cladribine tablets have fewer relapses (where new symptoms occur or existing symptoms get worse for 24 ...
  • Absence of latitudinal gradient in oligoclonal bands prevalence in Argentina 
    Negrotto, Laura; Marrodán, Mariano; Fiol, Marcela Paula; Gaitán, María Inés; Ysrraelit, María Célica; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Rojas, Juan Ignacio; Carrá, Adriana; Chertcoff, Aníbal; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Correale, Jorge (Elsevier, 2020-11)
    Background: Like MS prevalence, oligoclonal bands (OCB) frequency seems to follow a latitudinal gradient. Argentina is extensive, latitude-wise, and previous studies have not found an MS prevalence latitudinal gradient. ...
  • Accumulative risk of clinical event in high-risk radiologically isolated syndrome in Argentina: data from the nationwide registry RelevarEM 
    Rojas, Juan Ignacio; Pappolla, Agustín; Blaya, Patricio A.; Marrodán, Mariano; Ysrraelit, María Célica; Luetic, Geraldine G.; Liwacki, Susana; Barboza, Andrés G.; Burgos, Marcos; Cohen, Leila; Mainella, Carolina; Zanga, Gisela; Menichini, María Laura; Tavolini, Darío; Tkachuk, Verónica A.; López, Pablo Adrián; Leguizamon, Felisa; Knorre, Eduardo; Nofal, Pedro G.; Patrucco, Liliana (Springer, 2021-09-07)
    Introduction: We aimed to analyze the accumulative risk of MRI and OB factors for evolution from RIS to MS in subjects included in the Argentinean MS registry (NCT03375177). Methods: RIS subjects were identified according ...
  • Acting centrally or peripherally: A renewed interest in the central nervous system penetration of disease-modifying drugs in multiple sclerosis 
    Correale, Jorge; Halfon, Mario Javier; Jack, Dominic; Rubstein, Adrián; Villa, Andrés (Elsevier, 2021-09-14)
    With the recent approval of cladribine tablets, siponimod and ozanimod, there has been a renewed interest into the extent to which these current generation disease-modifying therapies (DMTs) are able to cross into the ...
  • Adaptation and validation of a Spanish version of the treatment burden questionnaire in patients with multiple sclerosis 
    Ysrraelit, María Célica; Fiol, Marcela Paula; Vazquez Peña, Fernando; Vanotti, Sandra; Terrasa, Sergio Adrián; Viet-Thi, Tran; Montori, Victor M.; Correale, Jorge (BioMed Central, 2019-08-27)
    Background: The Treatment Burden Questionnaire (TBQ) is a self-reported measure of the effect of treatment workload on patient wellbeing. We sought to validate the TBQ in Spanish and use it to estimate the burden of treatment ...
  • Aggressive multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM 
    Kohler, Matías; Kohler, Eduardo; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Correale, Jorge; Marrodán, Mariano; Gaitán, María Inés; Fiol, Marcela Paula; Negrotto, Laura; Ysrraelit, María Célica; Cristiano, Edgardo; Carrá, Adriana; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando (Elsevier, 2021-06-01)
    The objectives of the present study were to describe the frequency of aggressive multiple sclerosis (aMS) as well as to compare clinical and radiological characteristics in aMS and non-aMS patients included in RelevarEM ...
  • Are highly active and aggressive multiple sclerosis the same entity? 
    Correale, Jorge; Rush, Carolina A.; Barboza, Andrés G. (Frontiers Research Foundation, 2023-03-03)
    Resumen no disponible.
  • The Argentinean multiple sclerosis registry (RelevarEM): Methodological aspects and directions 
    Rojas, Juan Ignacio; Carrá, Adriana; Correale, Jorge; Cristiano, Edgardo; Fernandez Liguori, Nora; Alonso, Ricardo; Alvez Pinheiro, Amelia; Balbuena Aguirre, María Eugenia; Barboza, Andrés G.; Bestoso, Santiago; Blaya, Patricio A.; Burgos, Marcos; Cabrera, Lorena M.; Caride, Alejandro; Carnero Contentti, Edgar; Cohen, Leila; Curbelo, María Celeste; Deri, Norma; Divi, Pablo; Fiol, Marcela Paula; Fracaro, María Eugenia; Gaitán, María Inés; Hryb, Javier Pablo; Jacobo, Miguel; Knorre, Eduardo; Leguizamon, Felisa; Giunta, Diego Hernán; Serena, Marina Alonso; Doldan, María L.; de Lio, Guillermo F.; del V. Liwacki, Susana; López, Pablo Adrián; Luetic, Geraldine G.; Mainella, Carolina; Manzi, Ruben; Marrodán, Mariano; Martínez, Alejandra Diana; Míguez, Jimena S.; Negrotto, Laura; Nofal, Pedro G.; Parada Marcilla, Marcela; Pettinicchi, Juan Pablo; Silva, Berenice Anabel; Silva, Emanuel; Silveira, Facundo Oscar; Steinberg, Judith; Tavolini, Darío; Tizio, Santiago; Tkachuk, Verónica A.; Vázquez, Guido; Volman, Gabriel; Vrech, Carlos; Ysrraelit, María Célica; Zanga, Gisela; Garcea, Orlando; Patrucco, Liliana (Elsevier, 2019-05-15)
    Despite that different registries already exist in various countries in Europe and North America, no ongoing nationwide registry exists in Latin America (LATAM), a region where the disease behaves differently than in other ...
  • Argentinean recommendations on the identification of treatment failure in relapsing remitting multiple sclerosis patients 
    Cristiano, Edgardo; Alonso, Ricardo; Alvez Pinheiro, Amelia; Bacile, Elizabeth A.; Balbuena Aguirre, María Eugenia; Ballario, Carlos; Barboza, Andrés G.; Bestoso, Santiago; Burgos, Marcelo; Cáceres, Fernando; Carnero Contentti, Edgar; Carrá, Adriana; Crespo, Ernesto; Curbelo, María Celeste; Deri, Norma; Fernandez, Jorge; Fernandez Liguori, Nora; Fiol, Marcela Paula; Gaitán, María Inés; Garcea, Orlando; Giunta, Diego Hernán; Halfon, Mario Javier; Hryb, Javier Pablo; Jacobo, Miguel; Kohler, Eduardo; Linares, Ramiro; Luetic, Geraldine G.; Martínez, Alejandra Diana; Míguez, Jimena S.; Nofal, Pedro G.; Patrucco, Liliana; Piedrabuena, Raúl; Rojas, Juan Ignacio; Rotta Escalante, Roberto; Saladino, María Laura; Silva, Berenice Anabel; Sinay, Vladimiro; Steinberg, Judith; Tarulla, Adriana; Vétere, Santiago A.; Villa, Andrés; Vrech, Carlos; Ysrraelit, María Célica; Correale, Jorge (Elsevier, 2018-02-15)
    One of the biggest challenges in multiple sclerosis (MS) is the definition of treatment response/failure in order to optimize treatment decisions in affected patients. The objective of this consensus was to review how ...
  • Aspectos clínicos y demográficos de los pacientes con esclerosis múltiple secundaria progresiva en Argentina 
    Gaitán, María Inés; Marrodán, Mariano; Negrotto, Laura; Ysrraelit, María Célica; Miguez, Jimena; Alonso Serena, Marina; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Vrech, Carlos; Rojas, Juan Ignacio; Grupo de Trabajo Relevar EM (Fundación Revista Medicina (Buenos Aires), 2020)
    El objetivo del estudio fue evaluar los aspectos clínicos y demográficos de los pacientes con esclerosis múltiple (EM) secundaria progresiva (EMSP) en los pacientes incluidos en el Registro Argentino de EM (RelevarEM, ...
  • Assessing attacks and treatment response rates among adult patients with NMOSD and MOGAD: Data from a nationwide registry in Argentina 
    Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Criniti, Juan; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Liwacki, Susana; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Vrech, Carlos; Deri, Norma; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Leguizamon, Felisa; Luetic, Geraldine G.; Menichini, María Laura; Tavolini, Darío (Sage Publications, 2021-08-20)
    Abstract We aimed to examine treatment interventions implemented in patients experiencing neuromyelitis optica spectrum disorders (NMOSD) attacks (frequency, types, and response). Methods Retrospective study. Data on ...
  • Association between infections, the microbiome, vaccination, and neuromyelitis optica spectrum disorder 
    Carnero Contentti, Edgar; Correale, Jorge (Sage, 2022-07-28)
    Neuromyelitis optica spectrum disorder (NMOSD) is a devastating antibody-mediated condition of the central nervous system. As in other autoimmune diseases, there is considerable evidence to suggest that NMOSD arises from ...
  • Autoimmune Astrocytopathy 
    Correale, Jorge; Gaitán, María Inés (Springer, 2019-08-14)
    Astrocytes are the most abundant and heterogeneous type of glial cell in the Central Nervous System. In addition to their role maintaining physiological conditions stable in the CNS, they are recognized as early and highly ...
  • Barriers to access and utilization of multiple sclerosis care services in a large cohort of Latin American patients 
    Carnero Contentti, Edgar; Giachello, Susana; Correale, Jorge (Sage, 2021-01)
    Background: Multiple sclerosis (MS), is an emergent disease in Latin America (LATAM), which raises substantial socioeconomic challenges to a region where most countries remain as economies in development. Objective: To ...
  • Baseline Characteristics of Patients with Relapsing Multiple Sclerosis in ASCLEPIOS Phase 3 Trials of Ofatumumab Versus Teriflunomide (P3.2-096) 
    Kappos, Ludwig; Bar-Or, Amit; Cohen, Jeffrey A.; Comi, Giancarlo; Correale, Jorge; Coyle, Patricia K.; Cross, Anne H.; de Seze, Jerome; Montalban, Xavier; Selmaj, Krzysztof; Wiendl, Heinz; Leppert, David; Kerloeguen, Cecile; Willi, Roman; Häring, Dieter A.; Tomic, Davorka; Goodyear, Alexandra; Merschhemke, Martin; Hauser, Stephen L. (Lippincott Williams & Wilkins, 2019-04-16)
    Objective: To present the baseline characteristics of patients enrolled in the ASCLEPIOS I and II trials. Background: ASCLEPIOS I and II are two Phase 3 trials of identical design that are being conducted simultaneously ...
  • Bruton's tyrosine kinase inhibitors: a promising emerging treatment option for multiple sclerosis 
    Carnero Contentti, Edgar; Correale, Jorge (Taylor & Francis, 2020-12)
  • BTK inhibitors as potential therapies for multiple sclerosis 
    Correale, Jorge (Elsevier, 2021-08-19)
    Resumen no disponible
  • Cerebellar Ataxia With Extreme Photophobia Associated With Anti-SOX1 Antibodies 
    Alessandro, Lucas; Schachter, Daniel; Farez, Mauricio Franco; Varela, Francisco José (Sage, 2019-07)
    Anti-SOX1 antibodies are associated with diverse neurological syndromes, targeting both the central (paraneoplastic cerebellar degeneration) and peripheral nervous systems (Lambert Eaton myasthenic syndrome, paraneoplastic ...

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