Boyle, Rory; Koops, Elouise A.; Ances, Beau; Andrews, Elizabeth J.; Arenaza-Urquijo, Eider M.; Benjanin, Alexandre; Brickman, Adam M.; Buckley, Rachel F.; Clas, Giulia Solange; Costello, Emmet; Coughlan, Gillian T.; Conley, Alexander C.; Deng, Feng; de Paula Faria, Daniele; Edwards, Natalie; Flores-Aguilar, Lisi; Fortea, Juan; Saidi, Ladan Ghazi; Head, Elizabeth; Hom, Christy L.(Wiley, 2025-04-28)
Due to the high prevalence of Alzheimer's disease (AD) in adults with Down syndrome (DS), trisomy 21 is now considered a genetic form of AD (DSAD). A better understanding of factors that can prevent or delay AD is vital ...
Bateman, Randall J.; Li, Yan; McDade, Eric M.; Llibre-Guerra, Jorge J.; Clifford, David B.; Atri, Alireza; Mills, Susan L.; Santacruz, Anna M.; Wang, Guoqiao; Supnet, Charlene; Benzinger, Tammie L. S.; Gordon, Brian A.; Ibanez, Laura; Klein, Gregory; Baudler, Monika; Doody, Rachelle S.; Delmar, Paul; Kerchner, Geoffrey A.; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer's Disease–Trials Unit(Elsevier, 2025-04)
Background: Amyloid plaque removal by monoclonal antibody therapies slows clinical progression in symptomatic Alzheimer's disease; however, the potential for delaying the onset of clinical symptoms in asymptomatic people ...
Hub regions in the brain, recognized for their roles in ensuring efficient information transfer, are vulnerable to pathological alterations in neurodegenerative conditions, including Alzheimer's disease (AD). Computational ...
Background: Stroke is a leading cause of long-term disability worldwide. Timely and adequate rehabilitation is crucial for post-stroke recovery, but access is limited due to an overburdened healthcare system, medical ...
Background: Telestroke has proven efficacy in improving clinical outcomes by providing rapid access to specialized stroke care, particularly in remote areas. However, the global implementation of telestroke networks remains ...
Russo, María Julieta; Pavón, Hernán Marcelo; Deschle, Florencia; Marroquín, María Verónica; Aliaga, Orlando; Sampayo, María de la Paz(Elsevier, 2025-03-20)
En este trabajo investigamos la literatura existente acerca de la posibilidad de que algunos hallazgos clínicos puedan ser de utilidad para el diagnóstico de la presencia de contenido de conciencia en los pacientes con ...
We here present evidence-based guidelines for the pharmacological treatment of migraine. These guidelines, created by the Italian Society for the Study of Headache and the International Headache Society, aim to offer clear, ...
The development of vascular neurology as the primary specialty for stroke evaluation and treatment is a relatively recent advancement. Vascular neurology is well-established in the United States, ensuring most stroke ...
Martinez, Ramón; Muñoz-Venturelli, Paula; Ordunez, Pedro; Fregni, Felipe; Abanto, Carlos; Alet, Matías Javier; Alvarez, Tony Fabián; Amaya, Pablo; Ameriso, Sebastián Francisco; Arauz, Antonio; Barboza, Miguel A.; Bayona, Hernán; Bernabé-Ortiz, Antonio; Calleja, Juan; Cano-Nigenda, Vanessa; Carbonera, Leonardo Augusto; Carrillo-Larco, Rodrigo M.; Corredor, Angel; de Souza, Ana Cláudia; Rosales, Julieta Soledad(Elsevier, 2025-02-15)
Background: Despite substantial declines in burden over time, stroke remains a public health threat in the Americas. This study aimed to assess the current magnitude, trends, and disparities in the estimates of stroke ...
Llibre Guerra, Jorge J.; Fernandez, M. Victoria; Joseph-Mathurin, Nelly; Bian, Shijia; Carter, Kathleen; Li, Yan; Aschenbrenner, Andrew J.; Pottier, Cyril; Sigurdson, Wendy; McDade, Eric; Gordon, Brian A.; Renton, Alan E.; Benzinger, Tammie L. S.; Ibañez, Laura; Barthelemy, Nico; Dominantly Inherited Alzheimer Network(Nature Publishing Company, 2025-02-10)
We conducted an in-depth longitudinal study on an individual carrying the presenilin 2 p.Asn141Ile mutation, traditionally associated with dominantly inherited Alzheimer's disease (AD), who has remarkably remained asymptomatic ...
Latorre, Anna; van der Veen, S.; Pena, Ashley; Truong, Daniel; Erro, Roberto; Frucht, Steven; Ganos, Christos; Hallett, Mark; Perez-Duenas, Belen; Rossi, Malco Damián; Roze, Emmanuel; Vidailhet, Marie; Aj de Koning-Tijssen, Marina; Caviness, John N.(Elsevier, 2025-02-20)
Introduction: Recent new advances in myoclonus characterization and etiology justify an update of the 40-year-old respected classification of myoclonus proposed by Marsden, Hallett, and Fahn. New advances include genetic ...
Vermeiren, Marie R.; Calandri, Ismael Luis; van der Flier, Wiesje M.; van de Giessen, Elsmarieke; Ossenkoppele, Rik(Wiley, 2024)
Background: Recent advancements in Alzheimer’s disease (AD) biomarker researchand AD drug trials prompt reflection on the value and appropriate use of tau-PET infuture clinical practice and trials. We therefore conducted ...
Background
Multidomain lifestyle interventions have shown promise to slow cognitive decline and possibly prevent dementia. However, challenges arise in analyzing and interpreting treatment response when participants vary ...
Martín, María Eugenia; Martínez, Carlos; Worff, Iris; Belucci, María Agustina; Keller, Greta; Arruabarrena, Micaela María; Corvalàn, Nicolás; Clarens, María Florencia; Allegri, Ricardo Francisco; Crivelli, Lucía(Wiley, 2024)
Background: Dementia represents a significant health challenge, with evidencesuggesting that it can be potentially delayed or prevented through non-pharmacological interventions. There are different types of non-pharmaco ...
Background: Current evidence indicates that COVID-19 infection can lead toneurological complications that persist beyond 12 weeks of infection (long-COVID),often associated with cognitive decline. However, the underlying ...
Early detection of Mild Cognitive Impairment (MCI) is crucial for effective prevention. Traditional methods like expert judgment, clinical evaluations, and manual linguistic analyses are now complemented by Artificial ...