Olaf Witt, Sameer Farouk Sait; Diez, Blanca; Cardoso, Agustín; Reardon, David A.; Welsh, Liam; Shih, Kent C.; Baldini, Capucine; Massard, Christophe; Loriot, Yohann; Pant, Shubham; Sweiti, Hussein; Thomas, Shibu; Hammond, Constance; Najmi, Saltanat; Triantos, Spyros; Crow, Lauren; Geoerger, Birgit(American Society of Clinical Oncology, 2024-06)
Background: Erdafitinib is an oral selective pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor approved in the US for adult patients (pts) with locally advanced or metastatic urothelial carcinoma with ...
Cantarella, Florencia; Mendoza Bertelli, Andrea; Girotti, Romina; Marino, Ana Clara; Brest, Esteban; Dibarbora, Delfina; Mahmoud, Yamil; Veigas, Florencia; Enrico, Diego Hernan; Tsou, Florencia; Lacava, Juan A.; Piazzoni, Luciano; Riso, Aldo Alejandro; Martinengo, Gastón L.; Rodriguez, Andrés; Beguelin, Zenon; Cerrato, Sebastián; Jerez, Ignacio; Salanova, Rubén(American Society of Clinical Oncology, 2024-05-29)
Background: The analysis of somatic genomic alterations, evaluation of DNA mismatch repair (MMR) proteins, and examination of PD-L1 expression in tumor biopsies are crucial for prognosis and informed therapeutic decisions. ...
Background
Ewing Sarcoma (ES) tumors are malignant tumors mainly affecting pediatric patients. Extra-osseous primary sites are infrequent, being central nervous system (CNS)-ES extremely rare. Diverse differential ...
Introducción: Existen importantes discrepancias en el diagnóstico histopatológico de los aproximadamente 100 tipos de tumores cerebrales primarios. En los últimos años se han incorporado técnicas como la biología molecular ...
Background: Children ≤36 months with diffuse intrinsic pontine glioma (DIPG) have increased long-term survival (LTS, overall survival (OS) ≥24 months). Understanding distinguishing characteristics in this population is ...
Introduction: Standards for chemotherapy against choroid plexus tumors (CPT) have not yet been established.
Methods: CPT-SIOP-2000 (NCT00500890) was an international registry for all CPT nesting a chemotherapy randomization ...
Background
Diffuse intrinsic pontine glioma (DIPG) remains a clinico-radiologic diagnosis without routine tissue acquisition. Reliable imaging distinction between DIPG and other pontine tumors with potentially more favorable ...
Rabadán, Alejandra T.; Hernández, Diego; Varela, Analía; Diez, Blanca; Rubianes, Javier(Asociación Argentina de Neurocirugía, 2020)
The optic nerve glioma is a very uncommon entity in adult patients, with little information about its natural history and
therapeutical management. We report the case of a 27-year-old patient with acute involvement of the ...
Choroid Plexus Papillomas (CPP) is uncommon tumors of the CNS. Atypical CPPs represent an
intermediate-grade subtype (Grade II) introduced in the update 2007 of the WHO classification.
Distal spread of atypical CPPs ...
INTRODUCTION
Ewing Sarcoma (ES) is defined by molecular markers, being t(11,22) the most frequent. Intracranial ES/pPNET usually represent metastases from extracranial sites. Primary Central Nervous System (CNS) lesions ...