Neurooncología

Recent Submissions

  • Efficacy and safety of erdafitinib in pediatric patients with advanced solid tumors and FGFR alterations in the phase 2 RAGNAR trial 
    Olaf Witt, Sameer Farouk Sait; Diez, Blanca; Cardoso, Agustín; Reardon, David A.; Welsh, Liam; Shih, Kent C.; Baldini, Capucine; Massard, Christophe; Loriot, Yohann; Pant, Shubham; Sweiti, Hussein; Thomas, Shibu; Hammond, Constance; Najmi, Saltanat; Triantos, Spyros; Crow, Lauren; Geoerger, Birgit (American Society of Clinical Oncology, 2024-06)
    Background: Erdafitinib is an oral selective pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor approved in the US for adult patients (pts) with locally advanced or metastatic urothelial carcinoma with ...
  • Clinical efficacy of a next-generation sequencing (NGS) and immunohistochemistry (IHC) panel in patients with advanced cancer in Argentina. 
    Cantarella, Florencia; Mendoza Bertelli, Andrea; Girotti, Romina; Marino, Ana Clara; Brest, Esteban; Dibarbora, Delfina; Mahmoud, Yamil; Veigas, Florencia; Enrico, Diego Hernan; Tsou, Florencia; Lacava, Juan A.; Piazzoni, Luciano; Riso, Aldo Alejandro; Martinengo, Gastón L.; Rodriguez, Andrés; Beguelin, Zenon; Cerrato, Sebastián; Jerez, Ignacio; Salanova, Rubén (American Society of Clinical Oncology, 2024-05-29)
    Background: The analysis of somatic genomic alterations, evaluation of DNA mismatch repair (MMR) proteins, and examination of PD-L1 expression in tumor biopsies are crucial for prognosis and informed therapeutic decisions. ...
  • 6P Extraosseous central nervous system Ewing sarcoma: A single-center retrospective case series 
    Yorio, Florencia; Arakaki, Naomi; Alessandro, Lucas; Palomar, Nicolás; Diez, Blanca; Muggeri, Alejandro (ESMO, 2024-03)
    Background Ewing Sarcoma (ES) tumors are malignant tumors mainly affecting pediatric patients. Extra-osseous primary sites are infrequent, being central nervous system (CNS)-ES extremely rare. Diverse differential ...
  • Análisis del valor diagnóstico de la metilomica en tumores cerebrales primarios de una única institución 
    Yorio, Florencia; Cerrato, Sebastián; Calabrese, Bernadette; Palomar, Nicolás; Cardoso, Agustín; Arakaki, Naomi; Martinetto, Horacio; Diez, Blanca; Muggeri, Alejandro (Asociación Argentina de Oncología Clínica, 2023-12-15)
    Introducción: Existen importantes discrepancias en el diagnóstico histopatológico de los aproximadamente 100 tipos de tumores cerebrales primarios. En los últimos años se han incorporado técnicas como la biología molecular ...
  • Characteristics of children ≤36 months of age with DIPG: A report from the international DIPG registry 
    Bartlett, Allison L.; Lane, Adam; Chaney, Brooklyn; Yanez Escorza, Nancy; Black, Katie; Cochrane, Anne; Minturn, Jane; Bartels, Ute; Warren, Kathy; Hansford, Jordan; Ziegler, David; Diez, Blanca; Goldman, Stewart; Packer, Roger; Kieran, Mark; DeWire-Schottmiller, Mariko; Erker, Craig; Monje-Deisseroth, Michelle; Wagner, Lars; Koschmann, Carl (Oxford University Press, 2022-12-01)
    Background: Children ≤36 months with diffuse intrinsic pontine glioma (DIPG) have increased long-term survival (LTS, overall survival (OS) ≥24 months). Understanding distinguishing characteristics in this population is ...
  • Final results of the Choroid Plexus Tumor study CPT-SIOP-2000 
    Wolff, Johannes E.; Van Gool, Stefaan W.; Kutluk, Tezer; Diez, Blanca; Kebudi, Rejin; Timmermann, Beate; Garami, Miklos; Sterba, Jaroslav; Fuller, Gregory N.; Bison, Brigitte; Kordes, Uwe R. (Springer, 2022-02)
    Introduction: Standards for chemotherapy against choroid plexus tumors (CPT) have not yet been established. Methods: CPT-SIOP-2000 (NCT00500890) was an international registry for all CPT nesting a chemotherapy randomization ...
  • Manejo de lesiones incidentales de la glándula pineal 
    Muggeri, Alejandro; Calabrese, Bernadette; Yorio, Florencia; Cerrato, Sebastián; Diez, Blanca (Asociación Argentina de Neurocirugía, 2022-09-12)
  • Accuracy of Central Neuro-Imaging Review of DIPG Compared with Histopathology in the International DIPG Registry 
    Lazow, Margot A.; Fuller, Christine; DeWire-Schottmiller, Mariko; Lane, Adam; Bandopadhayay, Pratiti; Bartels, Ute; Bouffet, Eric; Cheng, Sylvia; Cohen, Kenneth J.; Cooney, Tabitha M.; Coven, Scott L.; Dholaria, Hetal; Diez, Blanca; Dorris, Kathleen; El-Ayadi, Moatasem; El-Sheikh, Ayman; Fisher, Paul G.; Fonseca, Adriana; Garcia Lombardi, Mercedes; Sevlever, Gustavo Emilio (Oxford, 2021-10-20)
    Background Diffuse intrinsic pontine glioma (DIPG) remains a clinico-radiologic diagnosis without routine tissue acquisition. Reliable imaging distinction between DIPG and other pontine tumors with potentially more favorable ...
  • Glioma del nervio óptico en paciente adulto con presentación hemorrágica tratado mediante abordaje endoscópico transesfenoidal extendido 
    Rabadán, Alejandra T.; Hernández, Diego; Varela, Analía; Diez, Blanca; Rubianes, Javier (Asociación Argentina de Neurocirugía, 2020)
    The optic nerve glioma is a very uncommon entity in adult patients, with little information about its natural history and therapeutical management. We report the case of a 27-year-old patient with acute involvement of the ...
  • An Attypical Choroid Plexus Papilloma of IV Ventricle with Dissemination to a Sacral Tarlov Cyst: A Case Report 
    Gentile, Aixa; Diez, Blanca; Cervio, Andrés Eduardo; Arakaki, Naomi; Cejas, Claudia Patricia (Remedy Publications, 2019-02-07)
    Choroid Plexus Papillomas (CPP) is uncommon tumors of the CNS. Atypical CPPs represent an intermediate-grade subtype (Grade II) introduced in the update 2007 of the WHO classification. Distal spread of atypical CPPs ...
  • Rare-43 primary central nervous system Ewing Sarcoma: a single institution experience 
    Yorio, Florencia; Alessandro, Lucas; Arakaki, Naomi; Palomar, Nicolás; Muggeri, Alejandro; Diez, Blanca (Oxford, 2019-11-11)
    INTRODUCTION Ewing Sarcoma (ES) is defined by molecular markers, being t(11,22) the most frequent. Intracranial ES/pPNET usually represent metastases from extracranial sites. Primary Central Nervous System (CNS) lesions ...