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Listar por autor "Falasco, Germán"
Mostrando ítems 1-12 de 12
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Falasco, Germán (2022-06-08)El flujo sanguíneo cerebral regional (FSCr) se encuentra normalmente acoplado a la actividad neuronal. Este proceso permite al cerebro optimizar el abastecimiento energético en condiciones de reposo y frente a un incremento ...
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Falasco, Germán; Damián, Andrés; Urrutia, Leandro; Niell, Nicolás; Lago, Graciela; Bérgamo, Yanina; Chrem Méndez, Patricio Alexis; Quagliata, Adriana; Bentancourt, Cecilia; Calandri, Ismael Luis; Cordero, Ismael; Ponce de León, Magdalena; Contreras, Valeria; Feuerstein, Viviana; Dansilio, Sergio; Allegri, Ricardo Francisco; Engler, Henry; Vazquez, Silvia (Bentham Science Publishers, 2021-11-15)Purpose: The aim of this study was to investigate the differences in early (EOAD) and late (LOAD) onset of Alzheimer´s disease, as well as glucose uptake, regional cerebral blood flow (R1), amyloid depositions, and functional ...
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Arena, Julieta E.; Urrutia, Leandro; Falasco, Germán; Ponce de León, Magdalena; Vázquez, Silvia; Rossi, Malco Damián; Merello, Marcelo (Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2021-03-05)Objective: To determine whether technetium-99m-labeled tropane derivative single-photon emission computed tomography (99mTcTRODAT-1 SPECT) provides results comparable to those of the less widely available, less accessible ...
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Tomasella, Eugenia; Falasco, Germán; Urrutia, Leandro; Bechelli, Lucila; Padilla, Lucia; Gelman, Diego M. (Springer, 2020-03-17)Background: Schizophrenia is a disease diagnosed by visible signs and symptoms from late adolescence to early adulthood. The etiology of this disease remains unknown. An objective diagnostic approach is required. Here, we ...
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de la Fuente, Verónica; Medina, Candela; Falasco, Germán; Urrutia, Leandro; Kravitz, Alexxai V.; Urbano, Francisco J.; Vázquez, Silvia; Pedreira, María Eugenia; Romano, Arturo (Nature Publishing Group, 2019-08-21)Memories are a product of the concerted activity of many brain areas. Deregulation of consolidation and reprocessing of mnemonic traces that encode fearful experiences might result in fear-related psychopathologies. Here, ...
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Uccelli, Nonthué Alejandra; Codagnone, Martín Gabriel; Traetta, Marianela Evelyn; Levanovich, Nadia; Rosato-Siri, María Victoria; Urrutia, Leandro; Falasco, Germán; Vázquez, Silvia; Pasquini, Juana María; Reinés, Analía Gabriela (Wiley, 2021-06-03)Atypical connectivity between brain regions and altered structure of the corpus callosum (CC) in imaging studies support the long-distance hypoconnectivity hypothesis proposed for autism spectrum disorder (ASD). The aim ...
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Ferroni, Nadina M.; Chertoff, Mariela J.; Alberca, Carolina D.; Berardino, Bruno G.; Gianatiempo, Octavio; Brahamian, Martin; Levi, Valeria; Urrutia, Leandro; Falasco, Germán; Cánepa, Eduardo T.; Sonzogni, Silvina V. (Elsevier, 2023-07-16)Early-life adversity, like perinatal protein malnutrition, increases the vulnerability to develop long-term alterations in brain structures and function. This study aimed to determine whether perinatal protein malnutrition ...
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Arena, Julieta E.; Urrutia, Leandro; Falasco, Germán; Ponce de León, Magdalena; Vázquez, Silvia (e-Century Pub, 2019-12-15)18F-FDOPA PET is one of the most widely used molecular imaging techniques to assess presynaptic dopaminergic activity. A variety of analytical methods have been developed to quantify 18F-FDOPA PET images and in most, the ...
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Muñiz, Javier Andrés; Facal, Carolina Lucía; Urrutia, Leandro; Clerici-Delville, Ramiro; Damianich, Ana; Ferrario, Juan Esteban; Falasco, Germán; Avale, María Elena (Frontiers Media S.A., 2022-09-05)Tau is a microtubule-associated protein predominantly expressed in neurons, which participates in microtubule polymerization and axonal transport. Abnormal tau metabolism leads to neurodegenerative diseases named tauopathies, ...
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de Francesco, Pablo Nicolás; Fernández, Gimena; Uriarte, Maia; Urrutia, Leandro; Ponce de León, Magdalena; Fehrentz, Jean-Alain; Falasco, Germán; Perello, Mario (Karger, 2022-07-29)Introduction: Ghrelin regulates a variety of functions by acting in the brain. The targets of ghrelin in the mouse brain have been mainly mapped using immunolabeling against c-Fos, a transcription factor used as a marker ...
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Tau mis-splicing correlates with motor impairments and striatal dysfunction in a model of tauopathy Damianich, Ana; Facal, Carolina Lucía; Muñiz, Javier Andrés; Mininni, Camilo; Soiza-Reilly, Mariano; Ponce de León, Magdalena; Urrutia, Leandro; Falasco, Germán; Ferrario, Juan Esteban; Avale, María Elena (Oxford, 2021-06-01)Tauopathies are neurodegenerative diseases caused by the abnormal metabolism of the microtubule associated protein Tau, which is highly expressed in neurons and critically involved in microtubule dynamics. In the adult ...
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Facal, Carolina Lucía; Fernández Bessone, Iván; Muñiz, Javier Andrés; Pereyra, A. Ezequiel; Pedroncini, Olivia; Páez Paz, Indiana; Clerici Delville, Ramiro; Arnaiz, Cayetana; Urrutia, Leandro; Falasco, Germán; Argañaraz, Carla Verónica; Saez, Trinidad; Marin Burgin, Antonia; Soiza Reilly, Mariano; Falzone, Tomás; Avale, María Elena (Cell Press, 2024-02-03)Abnormal tau accumulation is the hallmark of several neurodegenerative diseases, named tauopathies. Strategies aimed at reducing tau in the brain are promising therapeutic interventions, yet more precise therapies would ...
Mostrando ítems 1-12 de 12
Atribución 4.0 Internacional (CC BY 4.0)