Repositorio Dspace

Listar por autor "Wang, Guoqiao"

Listar por autor "Wang, Guoqiao"

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  • Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan 
    Luo, Jingqin; Agboola, Folasade; Grant, Elizabeth; Morris, John C.; Masters, Colin L.; Albert, Marilyn S.; Johnson, Sterling C.; McDade, Eric; Fagan, Anne M.; Benzinger, Tammie L.S.; Hassenstab, Jason; Bateman, Randall J.; Perrin, Richard J.; Wang, Guoqiao; Li, Yan; Gordon, Brian A.; Cruchaga, Carlos; Day, Gregory S.; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network (Oxford University Press, 2022-08-04)
    The temporal evolutions and relative orderings of Alzheimer disease biomarkers, including CSF amyloid-β42 (Aβ42), Aβ40, total tau (Tau) and phosphorylated tau181 (pTau181), standardized uptake value ratio (SUVR) from the ...
  • Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease 
    Llibre Guerra, Jorge J.; Li, H; Schindler, Suzanne E.; Gordon, Brian A.; Fagan, Anne M.; Morris, John C.; Benzinger, Tammie L.S.; Hassenstab, Jason; Wang, Guoqiao; Allegri, Ricardo Francisco; Berman, Sarah B.; Chhatwal, Jasmeer P.; Farlow, Martin R.; Holtzman, David M.; Jucker, Mathias; Levin, Johannes; Noble, James M.; Salloway, Stephen; Schofield, Peter R.; Karch, Celeste M.; Fox, Nick C.; Xiong, Chengjie; Bateman, Randall J.; McDade, Eric (American Medical Association, 2019-12-02)
    The amyloid/tau/neurodegeneration (A/T/N) framework uses cerebrospinal fluid (CSF) levels of total tau (tTau) as a marker of neurodegeneration and CSF levels of phosphorylated tau 181 (pTau181) as a marker of tau tangles. ...
  • Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN) 
    Aschenbrenner, Andrew J.; James, Bryan D.; McDade, Eric; Wang, Guoqiao; Lim, Yen Ying; Benzinger, Tammie L.S.; Cruchaga, Carlos; Goate, Alison M.; Xiong, Chengjie; Perrin, Richard J.; Buckles, Virginia; Allegri, Ricardo Francisco; Berman, Sarah B.; Chhatwal, Jasmeer P.; Fagan, Anne M.; Farlow, Martin R.; O’Connor, Antoinette; Ghetti, Bernardino; Graff-Radford, Neill R.; Goldman, Jill; Gräber, Susanne; Karch, Celeste M.; Lee, Jae-Hong; Levin, Johannes; Martins, Ralph N.; Masters, Colin L.; Mori, Hiroshi; Noble, James M.; Salloway, Stephen; Schofield, Peter R.; Morris, John C.; Bateman, Randall J.; Hassenstab, Jason; Dominantly Inherited Alzheimer Network; Dominantly Inherited Alzheimer Network (Wiley, 2020-06)
    Introduction: Although some members of families with autosomal dominant Alzheimer's disease mutations learn their mutation status, most do not. How knowledge of mutation status affects clinical disease progression is ...
  • Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial 
    Wagemann, Olivia; Liu, Haiyan; Wang, Guoqiao; Shi, Xinyu; Bittner, Tobias; Scelsi, Marzia A.; Farlow, Martin R.; Clifford, David B.; Supnet Bell, Charlene; Santacruz, Anna M.; Aschenbrenner, Andrew J.; Hassenstab, Jason J.; Benzinger, Tammie L.S.; Gordon, Brian A.; Coalier, Kelley A.; Cruchaga, Carlos; Ibanez, Laura; Perrin, Richard J.; Xiong, Chengjie; Li, Yan; Morris, John C.; Lah, James J.; Berman, Sarah B.; Roberson, Erik D.; van Dyck, Christopher H.; Galasko, Douglas; Gauthier, Serge; Hsiung, Ging-Yuek R.; Brooks, William S.; Pariente, Jérémie; Mummery, Catherine J.; Day, Gregory S.; Ringman, John M.; Chrem Méndez, Patricio Alexis; Dominantly Inherited Alzheimer Network–Trials Unit (American Medical Association, 2024-06-01)
    Importance: Effects of antiamyloid agents, targeting either fibrillar or soluble monomeric amyloid peptides, on downstream biomarkers in cerebrospinal fluid (CSF) and plasma are largely unknown in dominantly inherited ...
  • Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease 
    Joseph-Mathurin, Nelly; Wang, Guoqiao; Kantarci, Kejal; Jack Jr, Clifford R.; McDade, Eric; Hassenstab, Jason; Blazey, Tyler M.; Gordon, Brian A.; Su, Yi; Chen, Gengsheng; Massoumzadeh, Parinaz; Hornbeck, Russ C.; Allegri, Ricardo Francisco; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Chhatwal, Jasmeer P.; Dominantly Inherited Alzheimer Network (AAN, 2021-01-25)
    Objective: To investigate the inherent clinical risks associated with the presence of cerebral microhemorrhages (CMHs) or cerebral microbleeds (CMBs) and characterize individuals at high risk for developing hemorrhagic ...
  • Molecular neuroimaging in dominantly inherited versus sporadic early-onset Alzheimer's disease. 
    Iaccarino, Leonardo; Llibre Guerra, Jorge J.; McDade, Eric; Edwards, Lauren; Gordon, Brian A.; Benzinger, Tammie L.S.; Hassenstab, Jason; Kramer, Joel H.; Li, Yan; Miller, Bruce L.; Miller, Zachary; Morris, John C.; Mundada, Nidhi; Perrin, Richard J.; Rosen, Howard J.; Soleimani Meigooni, David; Strom, Amelia; Tsoy, Elena; Wang, Guoqiao; Xiong, Chengjie; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Vázquez, Silvia (Oxford University Press, 2024-05-03)
    Approximately 5% of Alzheimer's disease patients develop symptoms before age 65 (early-onset Alzheimer's disease), with either sporadic (sporadic early-onset Alzheimer's disease) or dominantly inherited (dominantly inherited ...
  • Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease 
    Vermunt, Lisa; Dicks, Ellen; Wang, Guoqiao; Dincer, Aylin; Flores, Shaney; Keefe, Sarah J.; Berman, Sarah B.; Cash, David M.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fox, Nick C.; Ghetti, Bernardino; Graff-Radford, Neill R.; Hassenstab, Jason; Karch, Celeste M.; Laske, Christoph; Levin, Johannes; Masters, Colin L.; Dominantly Inherited Alzheimer Network; Allegri, Ricardo Francisco (Oxford University Press, 2020-06-15)
    Structural grey matter covariance networks provide an individual quantification of morphological patterns in the brain. The network integrity is disrupted in sporadic Alzheimer's disease, and network properties show ...