Listar por tema "Ratones"

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  • Systemic Ghrelin Treatment Induces Rapid, Transient, and Asymmetric Changes in the Metabolic Activity of the Mouse Brain 
    de Francesco, Pablo Nicolás; Fernández, Gimena; Uriarte, Maia; Urrutia, Leandro; Ponce de León, Magdalena; Fehrentz, Jean-Alain; Falasco, Germán; Perello, Mario (Karger, 2022-07-29)
    Introduction: Ghrelin regulates a variety of functions by acting in the brain. The targets of ghrelin in the mouse brain have been mainly mapped using immunolabeling against c-Fos, a transcription factor used as a marker ...
  • Tau reduction with artificial microRNAs modulates neuronal physiology and improves tauopathy phenotypes in mice 
    Facal, Carolina Lucía; Fernández Bessone, Iván; Muñiz, Javier Andrés; Pereyra, A. Ezequiel; Pedroncini, Olivia; Páez Paz, Indiana; Clerici Delville, Ramiro; Arnaiz, Cayetana; Urrutia, Leandro; Falasco, Germán; Argañaraz, Carla Verónica; Saez, Trinidad; Marin Burgin, Antonia; Soiza Reilly, Mariano; Falzone, Tomás; Avale, María Elena (Cell Press, 2024-02-03)
    Abnormal tau accumulation is the hallmark of several neurodegenerative diseases, named tauopathies. Strategies aimed at reducing tau in the brain are promising therapeutic interventions, yet more precise therapies would ...