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Factors influencing recovery in a pediatric sample with disorders of consciousness: insights from an observational study.

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dc.contributor.author González, María Cecilia
dc.contributor.author Leguizamón, Florencia
dc.contributor.author Dei Vecchi, Lara
dc.contributor.author Andreu, Mauro Federico
dc.contributor.author Ferrea, Mónica
dc.date.accessioned 2024-07-16T12:11:03Z
dc.date.available 2024-07-16T12:11:03Z
dc.date.issued 2024-06-05
dc.identifier.citation González MC, Leguizamón F, Dei Vecchi L, Andreu M, Ferrea M. Factors influencing recovery in a pediatric sample with disorders of consciousness: insights from an observational study. Brain Inj. 2024 Jul 5:1-9. doi: 10.1080/02699052.2024.2372451. Epub ahead of print. es_ES
dc.identifier.uri https://doi.org/10.1080/02699052.2024.2372451
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/1150
dc.description.abstract Objective: To estimate rates and time to reach emergence of consciousness from vegetative state/unresponsive wakefulness syndrome (VS/UWS), and explore factors associated with improved recovery in children and adolescents with disorders of consciousness (DoC) following severe traumatic and non-traumatic brain injury. Methods: Analytical, retrospective, cohort study. Clinical records of consecutively referred patients admitted in VS/UWS to a neurological rehabilitation institute in Argentina, between 2005 and 2021 were reviewed. Seventy children and adolescents were included in the analysis. A specialized 12-week rehabilitation program was administered, and emergence was defined by scores ≥44 points on the Western Neuro Sensory Stimulation Profile (WNSSP), sustained for at least 3 weeks on consecutive weekly evaluations. Results: Emergence from VS/UWS to consciousness occurred within 5.4 (SD 2.6) weeks in almost one-third of patients. Multivariate Cox regression analysis showed emergence was significantly lower in patients with hypoxic ischemic encephalopathy compared to patients with other non-traumatic etiologies [HRadj 0.23 (95% CI 0.06-0.89); p = 0.03)]. Conclusions: Our findings reinforce growing evidence on the impact of etiology on DoC recovery in pediatric populations, ultimately influencing treatment and family-related decisions in child neurorehabilitation. es_ES
dc.language.iso eng es_ES
dc.publisher Informa Healthcare es_ES
dc.subject Consciousness Disorders es_ES
dc.subject Trastornos de la Conciencia es_ES
dc.subject Observational Study es_ES
dc.subject Estudio Observacional es_ES
dc.subject Argentina es_ES
dc.subject Neurological Rehabilitation es_ES
dc.subject Rehabilitación Neurológica es_ES
dc.subject Brain Injuries
dc.subject Lesiones Encefálicas
dc.title Factors influencing recovery in a pediatric sample with disorders of consciousness: insights from an observational study. es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.description.fil Fil: González, María Cecilia. Fleni. Departamento de Rehabilitación. Centro de Rehabilitación Infantil CRI-CETNA; Argentina.
dc.description.fil Fil: Leguizamón, Florencia. Fleni. Departamento de Rehabilitación. Centro de Rehabilitación Infantil CRI-CETNA; Argentina.
dc.description.fil Fil: Dei Vecchi, Lara. Fleni. Departamento de Rehabilitación. Centro de Rehabilitación Infantil CRI-CETNA; Argentina.
dc.description.fil Fil: Andreu, Mauro Federico. Universidad Nacional de la Matanza; Argentina.
dc.description.fil Fil: Ferrea, Mónica. Fleni. Departamento de Rehabilitación. Centro de Rehabilitación Infantil CRI-CETNA; Argentina.
dc.relation.ispartofCOUNTRY Inglaterra
dc.relation.ispartofCITY Londres
dc.relation.ispartofTITLE Brain injury
dc.relation.ispartofISSN 1362-301X
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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