dc.contributor.author |
Bistola, Vasiliki |
|
dc.contributor.author |
Farmakis, Dimitrios |
|
dc.contributor.author |
Tromp, Jasper |
|
dc.contributor.author |
Tay, Wan Ting |
|
dc.contributor.author |
Ouwerkerk, Wouter |
|
dc.contributor.author |
Angermann, Christiane E. |
|
dc.contributor.author |
Cleland, John G. F. |
|
dc.contributor.author |
Dahlström, Ulf |
|
dc.contributor.author |
Dickstein, Kenneth |
|
dc.contributor.author |
Ertl, Georg |
|
dc.contributor.author |
Hassanein, Mahmoud |
|
dc.contributor.author |
Liori, Sotiria |
|
dc.contributor.author |
Nikolopoulos, Petros |
|
dc.contributor.author |
Perrone, Sergio Víctor |
|
dc.contributor.author |
Ghadanfar, Mathieu |
|
dc.contributor.author |
Schweizer, Anja |
|
dc.contributor.author |
Obergfell, Achim |
|
dc.contributor.author |
Collins, Sean P. |
|
dc.contributor.author |
Lam, Carolyn S. P. |
|
dc.contributor.author |
Filippatos, Gerasimos |
|
dc.date.accessioned |
2024-11-28T13:59:37Z |
|
dc.date.available |
2024-11-28T13:59:37Z |
|
dc.date.issued |
2024-10-28 |
|
dc.identifier.citation |
Bistola V, Farmakis D, Tromp J, Tay WT, Ouwerkerk W, Angermann CE, et al. Hospitalized Advanced Heart Failure With Preserved vs Reduced Left Ventricular Ejection Fraction: A Global Perspective. JACC Heart Fail. febrero de 2025;13(2):229-47. |
es_ES |
dc.identifier.uri |
https://doi.org/10.1016/j.jchf.2024.09.009 |
|
dc.identifier.uri |
https://repositorio.fleni.org.ar/xmlui/handle/123456789/1274 |
|
dc.description.abstract |
Background: Outcomes of hospitalized patients with heart failure (HF) and characteristics of advanced HF stage may vary across left ventricular ejection fraction (LVEF) and world regions.
Objectives: This study sought to analyze characteristics of hospitalized advanced HF patients across LVEF spectrum, world regions, and country income.
Methods: Among 18,553 hospitalized patients with acute HF (7,902 new-onset HF and 10,651 decompensated chronic HF) enrolled in the global registry REPORT-HF (International Registry to Assess Medical Practice With Longitudinal Observation for Treatment of Heart Failure), we analyzed characteristics and outcomes of patients with advanced HF, defined as previously diagnosed HF; severe symptoms before current admission (NYHA functional class III/IV); and ≥1 HF-related hospitalization in the preceding 12 months, excluding the current. Differences among hospitalized advanced HF subgroups stratified by LVEF, world region, and country income were examined.
Results: Among 6,999 patients with decompensated chronic HF and available previous NYHA functional class and HF hospitalization status, 3,397 (48.5%; 18.3% of the total population) had advanced HF. Of these, 44.5% had severely reduced (≤30%), 34.9% mildly/moderately reduced (31%-49%), and 20.7% preserved (≥50%) LVEF. Patients from Eastern Europe had the lowest 1-year mortality (23%), whereas those from Southeast Asia had the highest (37%). Patients from lower-middle-income countries were younger, with shorter HF duration and lower comorbidity prevalence, received fewer beta-blockers and HF-devices, and had higher 1-year mortality (34%) than upper-middle- (26%) or high-income countries (27%; P = 0.018). Adjusted 1-year mortality risk did not differ among LVEF subgroups (all P > 0.05), nor did 1-year HF hospitalization rate (P = 0.56).
Conclusions: Hospitalized patients with advanced HF and preserved LVEF had similarly adverse outcomes as those with reduced LVEF. Patients from lower-middle-income countries had less implementation of HF therapies and higher 1-year mortality. |
es_ES |
dc.language.iso |
eng |
es_ES |
dc.publisher |
Elsevier |
es_ES |
dc.subject |
Insuficiencia Cardíaca |
es_ES |
dc.subject |
Heart Failure |
es_ES |
dc.subject |
Epidemiología |
es_ES |
dc.subject |
Epidemiology |
es_ES |
dc.subject |
Cardiology |
es_ES |
dc.subject |
Cardiología |
es_ES |
dc.title |
Hospitalized Advanced Heart Failure With Preserved vs Reduced Left Ventricular Ejection Fraction: A Global Perspective |
es_ES |
dc.type |
info:eu-repo/semantics/article |
es_ES |
dc.description.fil |
Fil: Perrone, Sergio Víctor. Fleni. Departamento de Neurología. Servicio de Cardiología; Argentina. |
|
dc.relation.ispartofVOLUME |
13 |
|
dc.relation.ispartofNUMBER |
2 |
|
dc.relation.ispartofPAGINATION |
229-247 |
|
dc.relation.ispartofCOUNTRY |
Estados Unidos |
|
dc.relation.ispartofCITY |
Nueva York |
|
dc.relation.ispartofTITLE |
JACC. Heart failure. |
|
dc.relation.ispartofISSN |
2213-1787 |
|
dc.type.snrd |
info:ar-repo/semantics/artículo |
es_ES |