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The Mixed Sellar Barrier: a New Subtype of this Novel Concept

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dc.contributor.author Villalonga, Juan Francisco
dc.contributor.author Ries Centeno, Tomás
dc.contributor.author Sáenz, Amparo
dc.contributor.author Solari, Domenico
dc.contributor.author Cervio, Andrés Eduardo
dc.contributor.author Campero, Álvaro
dc.date.accessioned 2019-09-18T14:58:36Z
dc.date.available 2019-09-18T14:58:36Z
dc.date.issued 2019-09-12
dc.identifier.citation Villalonga JF, Centeno TR, Sáenz A, Solari D, Cervio A, Campero A. The mixed sellar barrier: a new subtype of this novel concept. World Neurosurgery. September 2019. doi:10.1016/j.wneu.2019.09.027 en_US
dc.identifier.uri https://doi.org/10.1016/j.wneu.2019.09.027
dc.identifier.uri https://repositorio.fleni.org.ar/handle/123456789/43
dc.description.abstract BACKGROUND: The use of the recent concept of sellar barrier revealed that a specific group of patients were difficult to categorize. For this reason, we propose to add a new subtype: The mixed sellar barrier. The aim of this work is to define the new mixed barrier subtype and analyze this in a series of operated patients. METHODS: A retrospective study was carried out. From January to December 2018, 72 patients with pituitary adenomas underwent surgery by transsphenoidal approach. Patients with more than one surgery were excluded. Each patient MRI was analyzed and classified using the following criteria: Strong barrier (greater than 1 mm), weak barrier (less than 1 mm) and mixed (less than 1 mm in one region and greater than 1 mm in another part). RESULTS: Mixed sellar barrier is the coexistence of two types of sellar barrier (strong and weak). The presence of a mixed sellar barrier on MRI was associated with the presence of a mixed sellar barrier intraoperative (p<0.0001). By using the new MRI classification that includes the mixed sellar barrier, we found a stronger statistically significant association regarding the risk of CSF leak (for the extreme categories; i.e., strong and weak) compared to the original work. CONCLUSION: The new mixed sellar barrier subtype was precisely defined and illustrated. The correlation between MRI and intraoperative findings for this new subtype has been demonstrated in this study. A prospective study with a larger series of patients is required for validation. en_US
dc.language.iso eng en_US
dc.publisher Elsevier en_US
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Pituitary Neoplasms en_US
dc.subject Neoplasias Hipofisarias en_US
dc.subject Skull Base en_US
dc.subject Base del Cráneo en_US
dc.title The Mixed Sellar Barrier: a New Subtype of this Novel Concept en_US
dc.type info:eu-repo/semantics/publishedVersion
dc.type info:eu-repo/semantics/article en_US
dc.description.fil Fil: Villalonga, Juan Francisco. Universidad Nacional deTucumán. Facultad de Medicina. Laboratorio de Innovaciones Neuroquirúrgicas de Tucumán; Argentina. University of Naples Federico II. Department of Neuroscience and Reproductive and Odontostomatological Sciences; Italia.
dc.description.fil Fil: Ries Centeno, Tomás.Universidad Nacional deTucumán. Facultad de Medicina. Laboratorio de Innovaciones Neuroquirúrgicas de Tucumán; Argentina. Fleni. Departamento de Neurocirugía; Argentina.
dc.description.fil Fil: Sáenz, Amparo. Universidad Nacional deTucumán. Facultad de Medicina. Laboratorio de Innovaciones Neuroquirúrgicas de Tucumán; Argentina.
dc.description.fil Fil: Solari, Domenico. University of Naples Federico II. Department of Neuroscience and Reproductive and Odontostomatological Sciences; Italia
dc.description.fil Fil: Cervio, Andrés.Fleni. Departamento de Neurocirugía; Argentina
dc.description.fil Fil: Campero, Álvaro. Universidad Nacional de Tucumán. Facultad de Medicina. Laboratorio de Innovaciones Neuroquirúrgicas de Tucumán; Argentina. Hospital Padilla. Servicio de Neurocirugía; Argentina
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Nueva York
dc.relation.ispartofTITLE World Neurosurgery
dc.relation.ispartofISSN 1878-8769
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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