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BRMP-01. Awake cranial surgery with intraoperative language mapping for brain tumors. A single-center experience

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dc.contributor.author Cervio, Andrés Eduardo
dc.contributor.author Giovannini, Sebastián Juan María
dc.contributor.author Hasdeu, Sonia
dc.contributor.author Pertierra, Lucía
dc.contributor.author Diez, Blanca
dc.date.accessioned 2022-12-28T14:59:38Z
dc.date.available 2022-12-28T14:59:38Z
dc.date.issued 2021-11-12
dc.identifier.citation Cervio A, Giovannini A, Hasdeu S, Pertierra L, Diez B, BRMP-01. Awake cranial surgery with intraoperative language mapping for brain tumors. A single-center experience. Neuro-Oncology. 2021; 23 (Supplement 6): vi223, https://doi.org/10.1093/neuonc/noab196.894 es_ES
dc.identifier.uri https://doi.org/10.1093/neuonc/noab196.894
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/747
dc.description.abstract BACKGROUND Maximal safe resection of brain tumors affecting language areas has been a matter of increasing interest worldwide in the last decades. Functional MRI, tractography, and awake cranial surgery are standard procedures in our department since 2006. The aim of this study was to describe our experience in a series of 58 patients who underwent awake cranial surgery with intraoperative language mapping. METHODS Retrospective study of 58 adult patients who underwent awake surgery for brain tumors between January 2006 and January 2021. Preoperative neuropsychological assessment served as inclusion criteria. Language was evaluated according to the BDAE (Boston diagnostic aphasia examination) and WAB (Western aphasia battery) and strength according to the MRC (Medical Research Council) motor scale in the preoperative, immediate postoperative, and 3-months follow up. Functional MRI and tractography depicting white-matter tracts, neuronavigation, cortical and subcortical stimulation were performed in all cases. Conscious sedation was the anesthetic technique (propofol, fentanyl, and NSAIDs). Minimum follow-up was 6 months. FINDINGS The average age was 35 years (16–74). The anatomopathological findings were: low-grade glioma in 75,8% (n = 44), high-grade glioma in 15,6% (n = 9) and others in 8,6% (n = 5). No complications were registered during postoperative course. At the immediate postoperative evaluation 65% of patients presented with speech disturbances but at the 3-months follow up speech recovery was observed in all cases. Only 1 patient remained with moderate aphasia. mRS score at 3- months follow up was ≤ 1 in 96% of patients. Two patients had a persistent moderate hemiparesis. CONCLUSION Tumor resection in awake patients showed to be a safe procedure, and well tolerated by the patients. Preoperative planning of anatomical and functional aspects and intraoperative neurophysiological assessment are the cornerstones for pursuing maximal safe resection. es_ES
dc.language.iso eng es_ES
dc.publisher Oxford es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Intraoperative Neurophysiological Monitoring es_ES
dc.subject Monitorización Neurofisiológica Intraoperatoria es_ES
dc.subject Neuronavigation es_ES
dc.subject Neuronavegación es_ES
dc.title BRMP-01. Awake cranial surgery with intraoperative language mapping for brain tumors. A single-center experience es_ES
dc.type Presentation es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Cervio, Andrés Eduardo. Fleni. Departamento de Neurocirugía; Argentina.
dc.description.fil Fil: Giovannini, Sebastián Juan María. Fleni. Departamento de Neurocirugía; Argentina.
dc.description.fil Fil: Hasdeu, Sonia. Hospital Provincial Neuquén Dr. Castro Rendon; Argentina.
dc.description.fil Fil: Pertierra, Lucía. Fleni. Departamento de Neurología. Servicio de Neurología Cognitiva, Neuropsicología y Neuropsiquiatría; Argentina.
dc.description.fil Fil: Diez, Blanca. Fleni. Departamento de Neurología. Servicio de Neurooncología; Argentina.
dc.relation.ispartofVOLUME 23
dc.relation.ispartofNUMBER Suplemento 6
dc.relation.ispartofPAGINATION vi223
dc.relation.ispartofCOUNTRY Reino Unido
dc.relation.ispartofCITY Oxford
dc.relation.ispartofTITLE Neuro-oncology
dc.relation.ispartofISSN 1522-8517
dc.type.snrd Presentation es_ES

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