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Clinical Applicability of the Sellar Barrier Concept in Patients with Pituitary Apoplexy: Is It Possible?

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dc.contributor.author Pailler, José Ignacio
dc.contributor.author Villalonga, Juan Francisco
dc.contributor.author Ries Centeno, Tomás
dc.contributor.author Saenz, Amparo
dc.contributor.author Baldoncini, Matías
dc.contributor.author Pipolo, Derek Orlando
dc.contributor.author Cárdenas Ruiz-Valdepeñas, Eugenio
dc.contributor.author Kaen, Ariel
dc.contributor.author Hirtler, Lena
dc.contributor.author Roytowski, David
dc.contributor.author Solari, Domenico
dc.contributor.author Cervio, Andrés Eduardo
dc.contributor.author Campero, Álvaro
dc.date.accessioned 2023-09-05T14:31:28Z
dc.date.available 2023-09-05T14:31:28Z
dc.date.issued 2023-01-05
dc.identifier.citation Pailler, J.I., Villalonga, J.F., Ries-Centeno, T., Saenz, A., Baldoncini, M., Pipolo, D.O., Cárdenas Ruiz-Valdepeñas, E., Kaen, A., Hirtler, L., Roytowski, D., Solari, D., Cervio, A., Campero, A., 2023. Clinical Applicability of the Sellar Barrier Concept in Patients with Pituitary Apoplexy: Is It Possible? Life (Basel) 13, 158. https://doi.org/10.3390/life13010158 es_ES
dc.identifier.uri https://doi.org/10.3390/life13010158
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/820
dc.description.abstract There is evidence of association between sellar barrier thickness and intraoperative cerebrospinal fluid (CSF) leakage, impacting the postoperative prognosis of the patients. The aim of this study is to analyze the clinical applicability of the sellar barrier concept in a series of operated patients with pituitary apoplexy (PA). A retrospective study was conducted including 47 patients diagnosed with PA who underwent surgical treatment through a transsphenoidal approach. Brain magnetic resonance imaging (MRI) of the patients were evaluated and classified utilizing the following criteria: strong barrier (greater than 1 mm), weak barrier (less than 1 mm), and mixed barrier (less than 1 mm in one area and greater than 1 mm in another). The association between sellar barrier types and CSF leakage was analyzed, both pre- and intraoperatively. The preoperative MRI classification identified 10 (21.28%) patients presenting a weak sellar barrier, 20 patients (42.55%) with a mixed sellar barrier, and 17 patients (36.17%) exhibiting a strong sellar barrier. Preoperative weak and strong sellar barrier subtypes were associated with weak (p ≤ 0.001) and strong (p = 0.009) intraoperative sellar barriers, respectively. Strong intraoperative sellar barrier subtypes reduced the odds of CSF leakage by 86% (p = 0.01). A correlation between preoperative imaging and intraoperative findings in the setting of pituitary apoplexy has been observed. es_ES
dc.language.iso eng es_ES
dc.publisher MDPI AG es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.subject Pituitary Apoplexy es_ES
dc.subject Apoplejia Hipofisaria es_ES
dc.subject Cerebrospinal Fluid Leak es_ES
dc.subject Pérdida de Líquido Cefalorraquídeo es_ES
dc.subject Skull Base es_ES
dc.subject Base del Cráneo es_ES
dc.title Clinical Applicability of the Sellar Barrier Concept in Patients with Pituitary Apoplexy: Is It Possible? es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Ries Centeno, Tomás. Fleni. Departamento de Neurocirugía; Argentina.
dc.description.fil Fil: Cervio, Andrés Eduardo. Fleni. Departamento de Neurocirugía; Argentina.
dc.relation.ispartofVOLUME 13
dc.relation.ispartofNUMBER 1
dc.relation.ispartofPAGINATION 158
dc.relation.ispartofCOUNTRY Suiza
dc.relation.ispartofCITY Basilea
dc.relation.ispartofTITLE Life
dc.relation.ispartofISSN 2075-1729
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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