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Listar Enfermedades Desmielinizantes.artículos por autor "Marrodán, Mariano"

Listar Enfermedades Desmielinizantes.artículos por autor "Marrodán, Mariano"

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  • 2-Chlorodeoxyadenosine (Cladribine) preferentially inhibits the biological activity of microglial cells 
    Aybar, Florencia; Pérez, María Julia; Marcora, María Silvina; Samman, María Eugenia; Marrodán, Mariano; Pasquini, Juana María; Correale, Jorge (Elsevier Science, 2022-01-29)
    Cladribine (2CdA) is a synthetic chlorinated purine nucleoside analogue which acts as a pro-drug requiring intracellular phosphorylation to be activated. It is biologically active in selected cell types, which results in ...
  • Absence of latitudinal gradient in oligoclonal bands prevalence in Argentina 
    Negrotto, Laura; Marrodán, Mariano; Fiol, Marcela Paula; Gaitán, María Inés; Ysrraelit, María Célica; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Rojas, Juan Ignacio; Carrá, Adriana; Chertcoff, Aníbal; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Correale, Jorge (Elsevier, 2020-11)
    Background: Like MS prevalence, oligoclonal bands (OCB) frequency seems to follow a latitudinal gradient. Argentina is extensive, latitude-wise, and previous studies have not found an MS prevalence latitudinal gradient. ...
  • Accumulative risk of clinical event in high-risk radiologically isolated syndrome in Argentina: data from the nationwide registry RelevarEM 
    Rojas, Juan Ignacio; Pappolla, Agustín; Blaya, Patricio A.; Marrodán, Mariano; Ysrraelit, María Célica; Luetic, Geraldine G.; Liwacki, Susana; Barboza, Andrés G.; Burgos, Marcos; Cohen, Leila; Mainella, Carolina; Zanga, Gisela; Menichini, María Laura; Tavolini, Darío; Tkachuk, Verónica A.; López, Pablo Adrián; Lequizamon, Felisa; Knorre, Eduardo; Nofal, Pedro G.; Patrucco, Liliana (Springer, 2021-09-07)
    Introduction: We aimed to analyze the accumulative risk of MRI and OB factors for evolution from RIS to MS in subjects included in the Argentinean MS registry (NCT03375177). Methods: RIS subjects were identified according ...
  • Aggressive multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM 
    Kohler, Matías; Kohler, Eduardo; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Correale, Jorge; Marrodán, Mariano; Gaitán, María Inés; Fiol, Marcela Paula; Negrotto, Laura; Ysrraelit, María Célica; Cristiano, Edgardo; Carrá, Adriana; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando (Elsevier, 2021-06-01)
    The objectives of the present study were to describe the frequency of aggressive multiple sclerosis (aMS) as well as to compare clinical and radiological characteristics in aMS and non-aMS patients included in RelevarEM ...
  • The Argentinean multiple sclerosis registry (RelevarEM): Methodological aspects and directions 
    Rojas, Juan Ignacio; Carrá, Adriana; Correale, Jorge; Cristiano, Edgardo; Fernandez Liguori, Nora; Alonso, Ricardo; Alvez Pinheiro, Amelia; Balbuena Aguirre, María Eugenia; Barboza, Andrés G.; Bestoso, Santiago; Blaya, Patricio A.; Burgos, Marcos; Cabrera, Lorena M.; Caride, Alejandro; Carnero Contentti, Edgar; Cohen, Leila; Curbelo, María Celeste; Deri, Norma; Divi, Pablo; Fiol, Marcela Paula; Fracaro, María Eugenia; Gaitán, María Inés; Hryb, Javier Pablo; Jacobo, Miguel; Knorre, Eduardo; Leguizamon, Felisa; Giunta, Diego Hernán; Serena, Marina Alonso; Doldan, María L.; de Lio, Guillermo F.; del V. Liwacki, Susana; López, Pablo Adrián; Luetic, Geraldine G.; Mainella, Carolina; Manzi, Ruben; Marrodán, Mariano; Martínez, Alejandra Diana; Míguez, Jimena S.; Negrotto, Laura; Nofal, Pedro G.; Parada Marcilla, Marcela; Pettinicchi, Juan Pablo; Silva, Berenice Anabel; Silva, Emanuel D.; Silveira, Facundo; Steinberg, Judith; Tavolini, Darío; Tizio, Santiago; Tkachuk, Verónica A.; Vazquez, Guido; Volman, Gabriel; Vrech, Carlos; Ysrraelit, María Célica; Zanga, Gisela; Garcea, Orlando; Patrucco, Liliana (Elsevier, 2019-05-15)
    Despite that different registries already exist in various countries in Europe and North America, no ongoing nationwide registry exists in Latin America (LATAM), a region where the disease behaves differently than in other ...
  • Aspectos clínicos y demográficos de los pacientes con esclerosis múltiple secundaria progresiva en Argentina 
    Gaitán, María Inés; Marrodán, Mariano; Negrotto, Laura; Ysrraelit, María Célica; Miguez, Jimena; Alonso Serena, Marina; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Vrech, Carlos; Rojas, Juan Ignacio; Grupo de Trabajo Relevar EM (Fundación Revista Medicina (Buenos Aires), 2020)
    El objetivo del estudio fue evaluar los aspectos clínicos y demográficos de los pacientes con esclerosis múltiple (EM) secundaria progresiva (EMSP) en los pacientes incluidos en el Registro Argentino de EM (RelevarEM, ...
  • Assessing attacks and treatment response rates among adult patients with NMOSD and MOGAD: Data from a nationwide registry in Argentina 
    Carnero Contentti, Edgar; López, Pablo Adrián; Pettinicchi, Juan Pablo; Criniti, Juan; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Liwacki, Susana; Tkachuk, Verónica A.; Balbuena Aguirre, María Eugenia; Vrech, Carlos; Deri, Norma; Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica; Leguizamon, Felisa; Luetic, Geraldine G.; Menichini, María Laura; Tavolini, Darío (Sage Publications, 2021-08-20)
    Abstract We aimed to examine treatment interventions implemented in patients experiencing neuromyelitis optica spectrum disorders (NMOSD) attacks (frequency, types, and response). Methods Retrospective study. Data on ...
  • Clinical and demographic characteristics of male MS patients included in the national registry-RelevarEM. Does sex or phenotype make the difference in the association with poor prognosis? 
    Luetic, Geraldine G.; Menichini, María Laura; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María Célica; Fiol, Marcela Paula; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice Anabel; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica A.; Barboza, Andrés G. (Elsevier, 2021-11-17)
    Background In multiple sclerosis demographics there is a well-known female prevalence and male patients have been less specifically evaluated in clinical studies, though some clinical differences have been reported between ...
  • Clinical characteristics, course and prognosis of Multiple Sclerosis patients with epilepsy. A case control study: MS and epilepsy 
    Sánchez, M.; Marone, Abril; Silva, Walter H.; Marrodán, Mariano; Correale, Jorge (Elsevier, 2024-01-02)
    Background and purpose: Although more common than in the general population, seizures are an atypical manifestation of multiple sclerosis (MS) and their pathophysiology is not well understood. This study aims to examine ...
  • Clinical impact of gender and age at onset on disease trajectory in primary progressive multiple sclerosis patients 
    Camerlingo, Sebastián; Rubinstein, Fernando; Ysrraelit, María Célica; Correale, Jorge; Carnero Contentti, Edgar; Rojas, Juan Ignacio; Patrucco, Liliana; Del Valle Leguizamon, Felisa; Tkachuk, Verónica A.; Fernández Liguori, Nora; Cristiano, Edgardo; Mainella, Carolina; Zanga, Gisela; Carrá, Adriana; Marrodán, Mariano; Martínez, Alejandra Diana; Silva, Berenice Anabel; Alonso, Ricardo (Sage Publications, 2024-01-21)
    Background and objectives: Primary-progressive multiple sclerosis (PPMS) is characterized by gradual neurological deterioration without relapses. This study aimed to investigate the clinical impact of gender and age at ...
  • Clinically relevant increases in serum neurofilament light chain and glial fibrillary acidic protein in patients with Susac syndrome 
    Plantone, Domenico; Sabatelli, Eleonora; Locci, Sara; Marrodán, Mariano; Laakso, Sini M.; Mateen, Farrah J.; Feresiadou, Amalia; Buelens, Tom; Bianco, Assunta; Fiol, Marcela Paula; Correale, Jorge; Tienari, Pentti; Calabresi, Paolo; De Stefano, Nicola; Iorio, Raffaele (Wiley, 2023-06-19)
    Background and purpose: Serum levels of neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are promising neuro-axonal damage and astrocytic activation biomarkers. Susac syndrome (SS) is an ...
  • Differential diagnosis in acute inflammatory myelitis 
    Marrodán, Mariano; Hernandez, Micaela Anahí; Kohler, Alejandro Alfredo; Correale, Jorge (Elsevier, 2020-11)
    Introduction: Establishing differential diagnosis between different inflammatory causes of acute transverse myelitis (ATM) can be difficult. The objective of this study was to see which clinical, imaging or laboratory ...
  • Disease activity after discontinuation of disease-modifying therapies in patients with multiple sclerosis in Argentina: data from the nationwide registry RelevarEM 
    Zanga, Gisela; Portinari, Carla; Barber, Josefina; Ibañez, Tomas; Brolese, Lucía; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Deri, Norma; Tkachuk, Verónica A.; Vrech, Carlos; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Ysrraelit, María Célica; Marrodán, Mariano; Gaitán, María Inés; Correale, Jorge; RELEVAREM Study Group (Taylor & Francis, 2022-10-02)
    Introduction: The discontinuation of disease-modifying therapies (DMTs) in multiple sclerosis (MS) is commonly seen in real-world settings due to several factors. Area cover: The aim of this study is to describe the ...
  • Disease activity impacts disability progression in primary progressive multiple sclerosis 
    Marrodán, Mariano; Bensi, Catalina; Pappolla, Agustín; Rojas, Juan Ignacio; Gaitán, María Inés; Ysrraelit, María Célica; Negrotto, Laura; Fiol, Marcela Paula; Patrucco, Liliana; Cristiano, Edgardo; Farez, Mauricio Franco; Correale, Jorge (Elsevier, 2019-12-14)
    Background Although solid information on the natural history of primary progressive multiple sclerosis (PPMS) is available, evidence regarding impact of disease activity on PPMS progression remains controversial. Objective To ...
  • Emerging drugs for the treatment of adult MOG-IgG-associated diseases 
    Carnero Contentti, Edgar; Marrodán, Mariano; Correale, Jorge (Taylor & Francis, 2021-04-16)
    Resumen no disponible
  • Evaluation of the times of disability progression and related factors in patients with primary progressive multiple sclerosis from Argentina 
    Alonso, Ricardo; Garcea, Orlando; Rojas, Juan Ignacio; Alonso Serena, Marina; Lázaro, Luciana; López, Pablo Adrián; Casas, Magdalena; Tkachuk, Verónica A.; Steinberg, Judith; Barboza, Andrés G.; Martínez, Alejandra Diana; Ysrraelit, María Célica; Correale, Jorge; Marrodán, Mariano; Chertcoff, Aníbal; Deri, Norma; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Pestchanker, Claudia (Elsevier, 2022-01-02)
    Background PPMS (primary progressive multiple sclerosis) patients represent less than 10% of MS patients in Argentina, men and women were similarly affected and most of them had a severe functional impairment. More rapid ...
  • Frequency of new asymptomatic MRI lesions during attacks and follow-up of patients with NMOSD in a real-world setting 
    Carnero Contentti, Edgar; Lopez, Pablo A.; Tkachuk, Verónica; Vrech, Carlos; Zarate, María A.; Correale, Jorge; Deri, Norma; Luetic, Geraldine; Marrodán, Mariano; Pagani Cassara, Fátima; Tavolini, Darío; Ysrraelit, María Célica; Balbuena, María E.; Hryb, Javier; Chiganer, Edson; Leguizamon, Felisa; Knorre, Eduardo; Zanga, Gisela; Pestchanker, Claudia; Barboza, Andrés (Sage, 2023-07-25)
    Background: We aimed to assess the frequency of new asymptomatic lesions on brain and spinal imaging (magnetic resonance imaging (MRI)) and their association with subsequent relapses in a large cohort of neuromyelitis ...
  • Incidence of COVID-19 after vaccination in people with multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM 
    Rojas, Juan Ignacio; Luetic, Geraldine G.; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María Célica; Fiol, Marcela Paula; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice Anabel; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica A.; Barboza, Andrés G. (Elsevier B. V., 2022-12)
    The objective of the study was to evaluate the incidence of COVID-19 after complete vaccination in people with multiple sclerosis (PwMS) included in the Argentinean MS and NMOSD registry (RelevarEM, NCT03375177). Methods: ...
  • Interleukin-35 is a critical regulator of immunity during helminth infections associated with multiple sclerosis 
    Correale, Jorge; Marrodán, Mariano; Carnero Contentti, Edgar (Wiley, 2021-07-01)
    Multiple sclerosis (MS) is currently thought to arise by interactions between genetic susceptibility and environmental factors. Infections in general trigger autoimmune responses causing clinical manifestations of disease. ...
  • Mechanisms of Neurodegeneration and Axonal Dysfunction in Progressive Multiple Sclerosis 
    Correale, Jorge; Marrodán, Mariano; Ysrraelit, María Célica (MDPI, 2019-02-20)
    Multiple Sclerosis (MS) is a major cause of neurological disability, which increases predominantly during disease progression as a result of cortical and grey matter structures involvement. The gradual accumulation of ...

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