Espeland, Mark A.; Olson, Kay Loni; Tangney, Christy C.; Gitelman, Darren R.; Cleveland, Maryjo L.; Thro, Amber A.; Demesie, Yitbarek N.; Snyder, Heather M.; Whitmer, Rachel A.; Desai, Pankaja; Alam, Rifat; Crivelli, Lucía; Holland, Thomas M.; Preissle, Olivia; Raman, Rema; York, Michele K.; Baker, Laura; U.S. POINTER Study Group(Gerontological Society of America by Oxford University Press, 2026-05)
Background: Multidomain lifestyle interventions hold promise as approaches to slow aging. Deficit accumulation frailty indices (FIs) are increasingly used to capture aging processes. Frailty is highly associated with ...
Donaghy, Paul C.; Greenfinch, Gemma; Petrides, George; Kane, Joseph; Verberne, Hein J.; Taylor, John-Paul; O'Brien, John T.; Thomas, Alan J.; DLB Indicative Imaging Biomarker Study Group(Wiley on behalf of the Alzheimer's Association, 2026-03-04)
Introduction: The aim of this Delphi process was to develop consensus guidelines to support the effective use of striatal dopaminergic imaging and cardiac metaiodobenzylguanidine (MIBG) scintigraphy in the diagnosis of ...
Varani, Andrés Pablo; Bagliani, María Camila; Rossi, Malco Damián(Elsevier, 2025-12-11)
Parkinson's disease is characterized by a variety of motor and non-motor symptoms that arise from different regions of the central nervous system. Growing evidence indicates that pathological alterations in Parkinson's ...
Alarcon-Ruiz, Christoper A.; Goicochea, María Teresa(Brazilian Headache Society, 2025-12-31)
Persistent post-craniotomy headache (PPCH) is a frequent yet underrecognized complication of cranial surgery, often leading to long-term disability and impaired quality of life. Defined as a headache developing within seven ...
Domínguez-Carral, Jana; Domínguez Cobo, Ana María; Balsells, Sol; Aguilar Ros, Anna; Chang, Chu-Ting; Ludlam, William Grant; Yang, Kathryn; Bernardi, Katerina; Salazar Villacorta, Ainara; Di Pisa, Veronica; Lamagrande Casanova, Nuria; González Alguacil, Elena; De la Casa Fages, Beatriz; Chinigioli, Micaela; Okumura, Akihisa; Rodríguez, Josefina; Agarwal, Ayush; Muñoz Chesta, Daniela; Reynoso Osnayo, Carolina; Lin, Amy(Wiley-Liss, 2026-07)
Objective: Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first ...
Alzheimer's disease (AD) pathology begins years before symptoms emerge, making early detection essential. Eye tracking offers a rapid, non-invasive means of identifying early cognitive decline through oculomotor disturbances. ...
Most people with dementia live in low- and middle-income countries (LMICs), but scientific knowledge about dementia is dominated by Global North perspectives. This interdisciplinary article combines expertise from Latin ...
Background: Flow diversion is effective for unruptured distal anterior cerebral artery (DACA) aneurysms, yet comparative data between the Silk Vista Baby (SVB) and Pipeline Embolization Device (PED) in this challenging ...
Understanding the biological and genetic landscape of neurodegenerative diseases in diverse populations deepens our insight into complex pathophysiological mechanisms. Our laboratory, established 14 years ago in Buenos ...
Introduction: Rapid population aging in South America (SA) highlights the need for effective dementia detection strategies. Primary care is essential for early identification, yet no shared, regionally contextualized ...
Introduction: Biological, genetic, and sociocultural factors underlying cognitive resilience and resistance to pathology remain unexplored in Latin America. The Life-Course Epidemiology of Aging, Resilience, and Neurodegeneration ...
Correale, Jorge(Wiley on behalf of the International Society for Neurochemistry, 2026-04)
Recent advances, including single-cell transcriptomics, lineage tracing, and in vivo imaging, have unveiled the heterogeneity, plasticity, and functional versatility of astrocytes, microglia, oligodendrocytes, and Schwann ...
Este documento corresponde a la tercera parte del Primer Consenso Argentino sobre el manejo de la esquizofrenia y tiene como objetivo sintetizar la evidencia científica actualizada sobre los abordajes terapéuticos en ...
Este documento constituye la segunda parte del Primer Consenso Argentino sobre el Manejo de la Esquizofrenia y presenta una síntesis actualizada de la evidencia disponible sobre los aspectos clínicos y diagnósticos del ...
Background: Alzheimer's disease postmortem studies demonstrate that amyloid plaques and neurofibrillary tangles are present in subcortical regions.
Objective: To investigate longitudinal subcortical structural changes in ...
BackgroundAlthough levodopa is the gold standard treatment for Parkinson's disease (PD), its chronic use is associated with levodopa-induced dyskinesia (LID), a motor complication that impacts prognosis, quality of life, ...
Introduction: Despite less education being common in Latin America, there is no systematic review on the use of brief cognitive screening (BCS) tools in illiterate and low-educated adults in the region. We systematically ...
Magnetic resonance imaging (MRI) plays a central role in the diagnosis, differential diagnosis, and monitoring of neuroimmunological disorders, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder ...
Purpose of review: As the life expectancy of people with multiple sclerosis (PwMS) increases, the importance of recognizing and addressing specific needs and challenges faced by those undergoing age-related sex hormone ...