INTRODUCTION: This study investigates the evolution with disease progression and pathological correlates of peak width of skeletonized mean diffusivity (PSMD), a sensitive diffusion magnetic resonance imaging (MRI) marker ...
Ouriques Martins, Sheila Cristina; Ordunez, Pedro; Borelli, Wyllians Vendramini; Ovbiagele, Bruce; Urrutia, Victor C.; Abanto, Carlos; Alet, Matías Javier; Almarie, Bassel; Álvarez, Tony Fabián; Amaya, Pablo; Ameriso, Sebastian Francisco; Arauz-Gongora, Antonio; Barboza, Miguel A.; Bayona, Hernán; Calleja, Juan; Cano Nigenda, Vanessa; Carbonera, Leonardo Augusto; Carrillo Larco, Rodrigo M.; Constanzo, Freddy; Pujol Lereis, Virginia Andrea(Elsevier, 2026-05-22)
Stroke remains a leading cause of death and disability throughout the Americas, disproportionately impacting low-and middle-income countries and underserved populations. In this review, we examine the status of stroke ...
Martí, Maria Trinidad; Salas, Juan Cruz; Bártoli, Julia; Arakaki, Naomi; Cerrato, Sebastián; Yorio, Florencia; Delorme, Ricardo; Muggeri, Alejandro(Academia Argentina de Oncología Clínica, 2026-05-05)
La incidencia de metástasis extra sistema nervioso central (MESNC) en pacientes con gliomas es baja, del 0.4 al 11% dependiendo del tipo de glioma. No existen reportes acerca de la incidencia en la Argentina. El objetivo ...
A health emergency is defined as a scenario involving health conditions that pose a risk to humans, resulting in a substantial rise in disease, disability, and death. The most recent health emergency was the last COVID-19 ...
Background
Spontaneous intracranial hypotension (SIH) is a secondary headache disorder caused by spontaneous cerebrospinal fluid (CSF) leakage, typically from dural tears, meningeal diverticula, or CSF venous fistulas, ...
Jiménez, Daniel A.; Bagnati, Pablo M.; Flores Montes, Rosa Elena; Fernández, María Laura; Zuno Reyes, Angélica; Aguillón, David; Aláez Versón, Carmen; Becerra Solano, Luis Eduardo; Behrens, María Isabel; Branda, Kelly; Chrem Méndez, Patricio Alexis; Custodio, Nilton; Ducaine, Whitney; Dumois Petersen, Sofía; Figuera, Luis; Londoño Castaño, Marisol; Longoria, Erika Mariana; Matute, Esmeralda; Surace, Ezequiel Ignacio; Programa de asesoramiento genético en América Latina (PRAGA)(Wiley, 2026-05-27)
Autosomal dominant Alzheimer's disease (ADAD) represents a small but impactful subset of Alzheimer's cases. Asymptomatic individuals at genetic risk face substantial personal and family implications when considering ...
Guarnaschelli, María Flor; Marrodán, Mariano; Sosa, Brian Ezequiel; Perez Arana, Carolina I.; Farez, Mauricio Franco; Fiol, Marcela Paula; Ysrraelit, María Célica; Correale, Jorge(SAGE, 2026-04-29)
Background: Progression independent of relapse and MRI activity (PIRMA) is a major contributor to long-term disability in relapsing-remitting multiple sclerosis (RRMS). In Latin America, limited access to high-efficacy ...
Introduction: Sleep and circadian rest-activity rhythm (RAR) disruption may bidirectionally relate to Alzheimer's disease (AD). Down syndrome (DS), the most common genetic cause of AD, presents sleep disorders, yet RAR ...
Background and aims: Adaptive control ankle robotics is a promising but underexplored strategy for stroke rehabilitation. AMBLE is a wireless impedance-controlled ankle exoskeleton with foot switches that adapt dorsiflexion ...
Objective: To develop regression-based normative data for a set of widely used neuropsychological tests and to provide a freely accessible normative data calculator for use in Buenos Aires, Argentina. Methods: Participants ...
Background: While genetic testing in Movement Disorders (MD) has expanded enormously, access to genetic testing and genetic counseling remains asymmetric at the global scale. Guidance on efficient testing strategies for ...
Background: Social inequalities are key health determinants shaping Alzheimer’s disease (AD) progression. In dominantly inherited Alzheimer’s disease (DIAD), where genetic causes are established, the influence of socioeconomic ...
Background: LatAm FINGERS is a feasibility trial aimed at preventing cognitive decline in individuals at risk through lifestyle changes in Latin America, with its objectives aligned with the RE‐AIM (Reach, Effectiveness, ...
Gilbert, Afra; Gatto, Emilia M.; Chocobar, Nicolas; Seguí, Josefina; Crotti, Beatriz; Cubas Guillen, Jonathan Fernando; Merchan del Hierro, Xavier; Bacigalupe, Lucia; Persi, Gabriel; Melcon, Carlos Mario; O'Neill, Santiago; Múnera Martínez, Claudia Patricia; Sierra Sanjurjo, Natalia; Rojas, Galeno J.; Tribbia,Teresita Liliana; Taravini, Irene(Wiley, 2025-12-23)
Background: Yerba mate (YM), an infusion made from Ilex paraguariensis, is widely consumed in Argentina and other South American countries. Experimental studies have shown that YM enhances antioxidant defenses, increases ...
Background: Latin America (LA) faces heightened vulnerability to modifiable dementia risk factors. Early identification of at‐risk individuals is crucial for implementing effective preventive strategies. The Free and Cued ...
Rossi, Malco Damián; Stephen, Christopher D.; Damásio, Joana; Pedroso, José Luiz; Kuo, Sheng-Han; Lin, Chi-Ying R.; Ojo, Oluwadamilola; El-Jaafary, Shaimaa; Lee, Woong-Woo; Madoev, Harutyun; Barsottini, Orlando G.; Srivastava, Achal Kumar; Klein, Christine; Van de Warrenburg, Bart(Wiley, 2025-07-18)
The landscape of genetic ataxias is influenced by migration, population genetics, consanguinity, and founder effects, resulting in significant regional variation. Within the expanding domain of genetic ataxias, knowledge ...
BACKGROUND: Flow diverters (FDs) are increasingly used for cerebral aneurysms, including distal anterior cerebral artery (DACA) aneurysms, but comparative data between devices in this challenging location are limited. ...
Background: The Cognitive Function Index (CFI) was developed to identify individuals with Subjective Cognitive Decline (SCD), which is defined by the self‐perception of cognitive impairment, not detected in neuropsychological ...
Pucinelli de Souza Queiroz, Andréia; Pozzolo Pedro, Maria Olivia; Waisman Campos, Marcela; Torales, Julio; Ventriglio, Antonio; Castaldelli-Maia, João Mauricio(MDPI, 2025-07-15)
Cannabis is the most widely consumed illicit substance worldwide, with rising use particularly among adolescents and young adults. Accumulating evidence indicates that chronic cannabis use may negatively impact several ...
Introduction: White matter hyperintensities (WMH) are common in Down syndrome (DS), yet their longitudinal evolution and associations with Alzheimer's disease (AD) remain unclear.
Methods: Longitudinal MRI study, including ...