Espeland, Mark A.; Olson, Kay Loni; Tangney, Christy C.; Gitelman, Darren R.; Cleveland, Maryjo L.; Thro, Amber A.; Demesie, Yitbarek N.; Snyder, Heather M.; Whitmer, Rachel A.; Desai, Pankaja; Alam, Rifat; Crivelli, Lucía; Holland, Thomas M.; Preissle, Olivia; Raman, Rema; York, Michele K.; Baker, Laura; U.S. POINTER Study Group(Gerontological Society of America by Oxford University Press, 2026-05)
Background: Multidomain lifestyle interventions hold promise as approaches to slow aging. Deficit accumulation frailty indices (FIs) are increasingly used to capture aging processes. Frailty is highly associated with ...
Donaghy, Paul C.; Greenfinch, Gemma; Petrides, George; Kane, Joseph; Verberne, Hein J.; Taylor, John-Paul; O'Brien, John T.; Thomas, Alan J.; DLB Indicative Imaging Biomarker Study Group(Wiley on behalf of the Alzheimer's Association, 2026-03-04)
Introduction: The aim of this Delphi process was to develop consensus guidelines to support the effective use of striatal dopaminergic imaging and cardiac metaiodobenzylguanidine (MIBG) scintigraphy in the diagnosis of ...
Alzheimer's disease (AD) pathology begins years before symptoms emerge, making early detection essential. Eye tracking offers a rapid, non-invasive means of identifying early cognitive decline through oculomotor disturbances. ...
Most people with dementia live in low- and middle-income countries (LMICs), but scientific knowledge about dementia is dominated by Global North perspectives. This interdisciplinary article combines expertise from Latin ...
Understanding the biological and genetic landscape of neurodegenerative diseases in diverse populations deepens our insight into complex pathophysiological mechanisms. Our laboratory, established 14 years ago in Buenos ...
Introduction: Rapid population aging in South America (SA) highlights the need for effective dementia detection strategies. Primary care is essential for early identification, yet no shared, regionally contextualized ...
Introduction: Biological, genetic, and sociocultural factors underlying cognitive resilience and resistance to pathology remain unexplored in Latin America. The Life-Course Epidemiology of Aging, Resilience, and Neurodegeneration ...
Este documento corresponde a la tercera parte del Primer Consenso Argentino sobre el manejo de la esquizofrenia y tiene como objetivo sintetizar la evidencia científica actualizada sobre los abordajes terapéuticos en ...
Este documento constituye la segunda parte del Primer Consenso Argentino sobre el Manejo de la Esquizofrenia y presenta una síntesis actualizada de la evidencia disponible sobre los aspectos clínicos y diagnósticos del ...
Background: Alzheimer's disease postmortem studies demonstrate that amyloid plaques and neurofibrillary tangles are present in subcortical regions.
Objective: To investigate longitudinal subcortical structural changes in ...
Introduction: Despite less education being common in Latin America, there is no systematic review on the use of brief cognitive screening (BCS) tools in illiterate and low-educated adults in the region. We systematically ...
Bagnati, Pablo M.; Allegri, Ricardo Francisco; Demey, Ignacio; Bártoli, Gastón; Bérgamo, Yanina; Campos, Jorge; Castro, Diego M.; Chrem Méndez, Patricio Alexis; Cristalli, Diana Olga; Fernández, María Cecilia; Fernández, María Laura; García Lombardi, Juan Pablo; Kremer, Janus; Magrath Guimet, Nahuel; Ollari, Juan; Osa Sanz, Emilia; Russo, María Julieta; Surace, Ezequiel Ignacio; Vázquez, Silvia; Waisman Campos, Marcela(Vertex, 2026-01-10)
El Consenso Argentino para el diagnóstico de las demencias es una iniciativa de la Asociación Argentina de Psiquiatría Biológica (AAPB). Este documento tuvo como objetivo principal elaborar un instrumento eficiente para ...
Alessandra, Dodich; Andrea, Panzavolta; Giulia, Funghi; Claudia, Meli; Cristina, Festari; Thanos, Chatzikostopoulos; Christian, Chicherio; Clarens, María Florencia; Fabricio, Ferreira de Oliveira; Marco, Filardi; Agustin, Ibanez; Laura, Invernizzi; Thibaud, Lebouvier; Giancarlo, Logroscino; Sarah E., MacPherson; Riccardo, Manca; Camillo, Marra; Jordi A., Matias-Guiu; SIGNATURE Consortium(BioMed Central Ltd., 2025-12-06)
Background: Socio-cognitive assessment in neurocognitive disorders (NCDs) is rare in clinical practice and no consensus exists as to a uniform operationalization of socio-cognitive measures for NCDs in memory clinics. The ...
Dementia prevalence is increasing with aging worldwide, a leading cause of disability in Latin American Countries (LAC). Interestingly, physical performance has been reported as a predictor of cognitive decline, and gait ...
Background
Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia worldwide. It is characterized by progressive neuronal degeneration and the accumulation of beta‐amyloid plaques (Aβ) ...
The cortical asymmetry index evaluates the cortical thickness asymmetry between hemispheres. We investigated cortical asymmetry index in asymptomatic and symptomatic mutation carriers of autosomal dominant Alzheimer's ...
Background
Latin America (LA) faces high vulnerability to dementia risk factors. Early detection of cognitive decline, particularly in executive functions (EF), is crucial. The Trail Making Test (TMT) has limitations, ...
Calandri, Ismael Luis; Phillips, Jeffrey S.; Tideman, Pontus; Singleton, Ellen Hanna; La Joie, Renaud; van der Flier, Wiesje M.; Jonkman, Laura E.; Hansson, Oskar; Rabinovici, Gil D.; Pijnenburg, Yolande A. L.; Ossenkoppele, Rik; Mastenbroek, Sophie E.(Wiley, 2025-12-26)
Background
The behavioral variant of Alzheimer's disease (bvAD) is a rare atypical presentationcharacterized by early and prominent behavioral changes, clinically akin to the behavioral variant of fronto‐temporal dementia ...
Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts
and leukoencephalopathy (CADASIL), the most common hereditary small vessel
disease, leads to early-onset stroke and vascular cognitive ...
Russo, María Julieta; Sampayo, María de la Paz; Arias, Paula; García, Vanina; Gambero, Yanina; Maiarú, Mariano; Deschle, Florencia; Pavón, Hernán(MDPI, 2025-10-07)
Background: The Coma Recovery Scale-Revised (CRS-R) is the gold standard for diagnosing chronic disorders of consciousness (DoC); however, its clinical utility is limited by lengthy administration and the need for specialized ...