• The ICN-UN Battery: A Machine Learning-Optimized Tool for Expeditious Alzheimer's Disease Diagnosis 

  Barceló, Ernesto; Romero, Duban; Allegri, Ricardo Francisco; Meza, Eliana; Mosquera-Heredia, María I.; Vidal, Oscar M.; Silvera-Redondo, Carlos; Arcos-Burgos, Mauricio; Garavito-Galofre, Pilar; Vélez, Jorge I. (MDPI AG, 2025-11-28)

  Background/Objectives: Alzheimer's disease (AD) accounts for ~70% of global dementia cases, with projections estimating 139 million affected individuals by 2050. This increasing burden highlights the urgent need for ...
• Relative impact of multidomain lifestyle interventions on deficit accumulation frailty over 24 months in the U.S. POINTER trial 

  Espeland, Mark A.; Olson, Kay Loni; Tangney, Christy C.; Gitelman, Darren R.; Cleveland, Maryjo L.; Thro, Amber A.; Demesie, Yitbarek N.; Snyder, Heather M.; Whitmer, Rachel A.; Desai, Pankaja; Alam, Rifat; Crivelli, Lucía; Holland, Thomas M.; Preissle, Olivia; Raman, Rema; York, Michele K.; Baker, Laura; U.S. POINTER Study Group (Gerontological Society of America by Oxford University Press, 2026-05)

  Background: Multidomain lifestyle interventions hold promise as approaches to slow aging. Deficit accumulation frailty indices (FIs) are increasingly used to capture aging processes. Frailty is highly associated with ...
• Delphi consensus guidelines for the use of striatal dopaminergic imaging and cardiac metaiodobenzylguanidine (MIBG) scintigraphy for the diagnosis of dementia and mild cognitive impairment with Lewy bodies 

  Donaghy, Paul C.; Greenfinch, Gemma; Petrides, George; Kane, Joseph; Verberne, Hein J.; Taylor, John-Paul; O'Brien, John T.; Thomas, Alan J.; DLB Indicative Imaging Biomarker Study Group (Wiley on behalf of the Alzheimer's Association, 2026-03-04)

  Introduction: The aim of this Delphi process was to develop consensus guidelines to support the effective use of striatal dopaminergic imaging and cardiac metaiodobenzylguanidine (MIBG) scintigraphy in the diagnosis of ...
• Eye tracking as a diagnostic tool in Alzheimer's disease, mild cognitive impairment, and related dementias: a systematic review 

  Verón, Gustavo Luis; Juantorena, Gustavo Ezequiel; Keller, Greta; Crivelli, Lucía; Kamienkowski, Juan Esteban (Wiley, 2025-12-30)

  Alzheimer's disease (AD) pathology begins years before symptoms emerge, making early detection essential. Eye tracking offers a rapid, non-invasive means of identifying early cognitive decline through oculomotor disturbances. ...
• Scientific knowledge about dementia : From the Global South to the world 

  Daly, Timothy; López Barrenechea, Ignacio; Vergara, Paulina; Arshad, Faheem; Paplikar, Avanthi; Chaudhuri, Aparajita Ray; Crivelli, Lucía; Ibañez, Agustín; Alladi, Suvarna; Slachevsky, Andrea (John Wiley & Sons, Ltd., 2026-03)

  Most people with dementia live in low- and middle-income countries (LMICs), but scientific knowledge about dementia is dominated by Global North perspectives. This interdisciplinary article combines expertise from Latin ...
• Dementia screening protocol for primary care in South America : a Delphi consensus study 

  Custodio, Belen; Montesinos, Rosa; Caramelli, Paulo; Calandri, Ismael Luis; Dozzi Brucki, Sonia María; Suemoto, Claudia Kimie; Allegri, Ricardo Francisco; Slachevsky, Andrea; Parodi, Jose F.; Morsch, Patricia; Willets, Clarissa; Cuba Fuentes, María Sofía; Custodio, Nilton (Frontiers Editorial Office, 2026-04-08)

  Introduction: Rapid population aging in South America (SA) highlights the need for effective dementia detection strategies. Primary care is essential for early identification, yet no shared, regionally contextualized ...
• A harmonized framework for studying exceptional cognitive aging in Latin America 

  Crivelli, Lucía; Fernández, Rodrigo Sebastián; Corvalán, Nicolás; Sosa, Ana Luisa; Acosta, Daisy; Agnoletti, Giulia; Surace, Ezequiel Ignacio; Acosta, Issac; Caramelli, Paulo; Aguillón, David; Leniz Martelli, Javiera; Duque Peñailillo, Lissette; Custodio, Nilton; Charamelo Baieti, Ana; Damian, Andrés; Llibre Rodríguez, Juan J.; Allegri, Ricardo Francisco; Prina, Mathew; Rogalski, Emily; Ibañez, Laura (John Wiley & Sons, 2026-04-14)

  Introduction: Biological, genetic, and sociocultural factors underlying cognitive resilience and resistance to pathology remain unexplored in Latin America. The Life-Course Epidemiology of Aging, Resilience, and Neurodegeneration ...
• Primer Consenso Argentino en Esquizofrenia : tercera parte. Lineamientos para el abordaje integral del tratamiento 

  Corrales, Alejo; Abadi, Andrea; Bartoli, Gastón; Benavente Pinto, Carlos; Cabrera, Adrián; Camino, Sebastián; Corral, Ricardo; Delmonte, Guillermo; García Bonetto, Gerardo; Garay, Cristian Javier; Gargoloff, Damián; Gargoloff, Pedro; Goldchuk, Aníbal; Iveli, María Florencia; Jufe, Gabriela; Lamaison, Fabián; Leiderman, Eduardo; López Mato, Andrea; Marengo, Eliana; Waisman Campos, Marcela (Polemos, 2026-04-10)

  Este documento corresponde a la tercera parte del Primer Consenso Argentino sobre el manejo de la esquizofrenia y tiene como objetivo sintetizar la evidencia científica actualizada sobre los abordajes terapéuticos en ...
• Primer Consenso Argentino para el Manejo de la Esquizofrenia : Segunda Parte. Consideraciones clínicas y diagnósticas 

  Corrales, Alejo; Abadi, Andrea; Bartoli, Gastón; Benavente Pinto, Carlos; Cabrera, Adrián; Camino, Sebastián; Corral, Ricardo; Delmonte, Guillermo; García Bonetto, Gerardo; Garay, Cristian Javier; Gargoloff, Damián; Gargoloff, Pedro; Goldchuk, Aníbal; Iveli, María Florencia; Jufe, Gabriela; Lamaison, Fabián; Leiderman, Eduardo; López Mato, Andrea; Marengo, Eliana; Waisman Campos, Marcela (Polemos, 2026-01-10)

  Este documento constituye la segunda parte del Primer Consenso Argentino sobre el Manejo de la Esquizofrenia y presenta una síntesis actualizada de la evidencia disponible sobre los aspectos clínicos y diagnósticos del ...
• Longitudinal subcortical volume changes and their correlations with multiple PET and fluid biomarkers in dominantly inherited Alzheimer's disease 

  Choo, Il Han; Park, Hoyoung; Gordon, Brian A.; Bateman, Randall J.; Dominantly Inherited Alzheimer Network; Daniels, Alisha; Courtney, Laura; Ziegemeier, Angela; Skrbec, Karina; Hellm, Cortaiga; Martin, Mariana; Ziegemeier, Ellen; Bartzel, Jamie; McDade, Eric; Libre-Guerra, Jorge J.; Supnet Bell, Charlene; Xiong, Chengie; Chrem Méndez, Patricio Alexis; Surace, Ezequiel Ignacio; Vázquez, Silvia; Allegri, Ricardo Francisco (Elsevier, 2026-04)

  Background: Alzheimer's disease postmortem studies demonstrate that amyloid plaques and neurofibrillary tangles are present in subcortical regions. Objective: To investigate longitudinal subcortical structural changes in ...
• Brief Cognitive Screening Tools for Dementia in Low-Educated Population from South America : A Systematic Review 

  Chambergo Michilot, Diego; Custodio, Nilton; Montesinos, Rosa; Custodio, Belen; Cahuapaza Gutierrez, Nelson Luis; Caramelli, Paulo; Calandri, Ismael Luis; Dozzi Brucki, Sonia María; Suemoto, Claudia Kimie; Allegri, Ricardo Francisco; Slachevsky, Andrea; Parodi, Jose F. (Karger, 2025-09-29)

  Introduction: Despite less education being common in Latin America, there is no systematic review on the use of brief cognitive screening (BCS) tools in illiterate and low-educated adults in the region. We systematically ...
• Consenso Argentino para el diagnóstico de las demencias. Primera parte : introducción, metodología de trabajo, escenario actual y algoritmos diagnósticos 

  Bagnati, Pablo M.; Allegri, Ricardo Francisco; Demey, Ignacio; Bártoli, Gastón; Bérgamo, Yanina; Campos, Jorge; Castro, Diego M.; Chrem Méndez, Patricio Alexis; Cristalli, Diana Olga; Fernández, María Cecilia; Fernández, María Laura; García Lombardi, Juan Pablo; Kremer, Janus; Magrath Guimet, Nahuel; Ollari, Juan; Osa Sanz, Emilia; Russo, María Julieta; Surace, Ezequiel Ignacio; Vázquez, Silvia; Waisman Campos, Marcela (Vertex, 2026-01-10)

  El Consenso Argentino para el diagnóstico de las demencias es una iniciativa de la Asociación Argentina de Psiquiatría Biológica (AAPB). Este documento tuvo como objetivo principal elaborar un instrumento eficiente para ...
• International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative 

  Alessandra, Dodich; Andrea, Panzavolta; Giulia, Funghi; Claudia, Meli; Cristina, Festari; Thanos, Chatzikostopoulos; Christian, Chicherio; Clarens, María Florencia; Fabricio, Ferreira de Oliveira; Marco, Filardi; Agustin, Ibanez; Laura, Invernizzi; Thibaud, Lebouvier; Giancarlo, Logroscino; Sarah E., MacPherson; Riccardo, Manca; Camillo, Marra; Jordi A., Matias-Guiu; SIGNATURE Consortium (BioMed Central Ltd., 2025-12-06)

  Background: Socio-cognitive assessment in neurocognitive disorders (NCDs) is rare in clinical practice and no consensus exists as to a uniform operationalization of socio-cognitive measures for NCDs in memory clinics. The ...
• Gait Speed is Associated with Executive Function in Latin American Older Adults from LatAmFINGERS 

  Gutiérrez, Myriam; Marroig, Alejandra; Delgado, Carolina; Slachevsky, Andrea; Charamelo, Ana; Aguillon Niño, David Fernando; Crivelli, Lucía (Oxford, 2025-12)

  Dementia prevalence is increasing with aging worldwide, a leading cause of disability in Latin American Countries (LAC). Interestingly, physical performance has been reported as a predictor of cognitive decline, and gait ...
• Cortical asymmetry in autosomal dominant Alzheimer's disease progression 

  Pérez-Millan, Agnès; Falgàs, Neus; Bosch, Beatriz; Borrego-Écija, Sergi; Antonell, Anna; Fernández-Villullas, Guadalupe; Esteller-Gauxax, Diana; Tort-Merino, Adrià; Bargalló, Núria; Balasa, Mircea; Lladó, Albert; Aguillon, David; Chrem Méndez, Patricio Alexis; Day, Gregory S.; Devenney, Emma; Huey, Edward D.; Ikeuchi, Takeshi; Jucker, Mathias; Kasuga, Kensaku; Dominantly Inherited Alzheimer Network (DIAN) (Oxford University Press, 2025-12-19)

  The cortical asymmetry index evaluates the cortical thickness asymmetry between hemispheres. We investigated cortical asymmetry index in asymptomatic and symptomatic mutation carriers of autosomal dominant Alzheimer's ...
• Executive Functions in Latin American Older Adults: Exploring the Concept Shifting Test and Its Relationship with the APOE Gene in a Cross‐Sectional Sample from the LatAm‐FINGERS Study 

  Melillo Cardoso, Davi; Vasconcelos Friedlander, Clarisse; Sanches Yassuda, Monica; Cruz de Souza, Leonardo; Crivelli, Lucía; Kimie Suemoto, Claudia; Martin, Maria Eugenia; Calandri, Ismael Luis; Acosta‐Baena, Natalia; Surace, Ezequiel Ignacio; Damian, Andrés; Da Graça Morais Martin, Maria; Vigil‐Martinez, Ana; Henrique Cançado, Gustavo; Salinas‐Contreras, Rosa Maria; Custodio, Belen; Cusicanqui, María Isabel; Delgado, Carolina; Sevlever, Gustavo Emilio; Allegri, Ricardo Francisco (Wiley, 2025-12-26)

  Background Latin America (LA) faces high vulnerability to dementia risk factors. Early detection of cognitive decline, particularly in executive functions (EF), is crucial. The Trail Making Test (TMT) has limitations, ...
• Cognitive and neuroimaging trajectories in the behavioral variant of Alzheimer's disease 

  Calandri, Ismael Luis; Phillips, Jeffrey S.; Tideman, Pontus; Singleton, Ellen Hanna; La Joie, Renaud; van der Flier, Wiesje M.; Jonkman, Laura E.; Hansson, Oskar; Rabinovici, Gil D.; Pijnenburg, Yolande A. L.; Ossenkoppele, Rik; Mastenbroek, Sophie E. (Wiley, 2025-12-26)

  Background The behavioral variant of Alzheimer's disease (bvAD) is a rare atypical presentationcharacterized by early and prominent behavioral changes, clinically akin to the behavioral variant of fronto‐temporal dementia ...
• Clinical Validation of the SECONDs Tool for Evaluating Disorders of Consciousness in Argentina 

  Russo, María Julieta; Sampayo, María de la Paz; Arias, Paula; García, Vanina; Gambero, Yanina; Maiarú, Mariano; Deschle, Florencia; Pavón, Hernán (MDPI, 2025-10-07)

  Background: The Coma Recovery Scale-Revised (CRS-R) is the gold standard for diagnosing chronic disorders of consciousness (DoC); however, its clinical utility is limited by lengthy administration and the need for specialized ...
• Associations of lifestyle factors with amyloid pathology in persons without dementia 

  Oomens, Julie E.; Vos, Stephanie Jb; Maserejian, Nancy N.; Boada, Mercè; Didic, Mira; Engelborghs, Sebastiaan; Fladby, Tormod; van der Flier, Wiesje M.; Frisoni, Giovanni B.; Fröhlich, Lutz; Gill, Kiran Dip; Grimmer, Timo; Hort, Jakub; Allegri, Ricardo Francisco; Alzheimer's Disease Neuroimaging Initiative (ADNI); A4 Study group; Dominantly Inherited Alzheimer Network (DIAN); European Prevention of Alzheimer's Dementia (EPAD) consortium, Fundació ACE Healthy Brain Initiative (FACEHBI); Japan Alzheimer's Disease Neuroimaging Initiative (J-ADNI), Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease (KBASE); Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) research group (Sage, 2025-11-13)

  BackgroundThe association between lifestyle factors and Alzheimer's disease (AD) pathophysiology remains incompletely understood.ObjectiveThe aim of this study was to assess the association of alcohol consumption, smoking ...
• Persistent neurological sequelae in children and adolescents after SARS-CoV-2: a scoping review 

  Zouari Mallouli, Salma; Munblit, Daniel; Iakovleva, Ekaterina; Winkler, Andrea Sylvia; Fornari, Arianna; Helbok, Raimund; Struhal, Walter; Beretta, Simone; De Groote, Wouter; Curatoli, Chiara; Lanza, Martina; Ericka, Fink; Crivelli, Lucía; Giussani, Giorgia; Wasay, Mohammad; Walha, Olfa Chakroun; Safi, Faiza; Leonardi, Matilde; Allegri, Ricardo Francisco; Guekht, Alla (Springer, 2025-10-31)

  Objectives: For the past five years, COVID-19 has not only been a priority for health planning but also a hotspot for clinical research. Yet, the weight of the worldwide COVID-19 pandemic arises from the critical phase ...

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