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ListarEnfermedades Desmielinizantes.artículos por tema "Multiple Sclerosis"

ListarEnfermedades Desmielinizantes.artículos por tema "Multiple Sclerosis"

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  • Absence of latitudinal gradient in oligoclonal bands prevalence in Argentina 
    Negrotto, Laura; Marrodán, Mariano; Fiol, Marcela Paula; Gaitán, María Inés; Ysrraelit, María Célica; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Cristiano, Edgardo; Rojas, Juan Ignacio; Carrá, Adriana; Chertcoff, Aníbal; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando; Correale, Jorge (Elsevier, 2020-11)
    Background: Like MS prevalence, oligoclonal bands (OCB) frequency seems to follow a latitudinal gradient. Argentina is extensive, latitude-wise, and previous studies have not found an MS prevalence latitudinal gradient. ...
  • Accumulative risk of clinical event in high-risk radiologically isolated syndrome in Argentina: data from the nationwide registry RelevarEM 
    Rojas, Juan Ignacio; Pappolla, Agustín; Blaya, Patricio A.; Marrodán, Mariano; Ysrraelit, María Célica; Luetic, Geraldine G.; Liwacki, Susana; Barboza, Andrés G.; Burgos, Marcos; Cohen, Leila; Mainella, Carolina; Zanga, Gisela; Menichini, María Laura; Tavolini, Darío; Tkachuk, Verónica A.; López, Pablo Adrián; Lequizamon, Felisa; Knorre, Eduardo; Nofal, Pedro G.; Patrucco, Liliana (Springer, 2021-09-07)
    Introduction: We aimed to analyze the accumulative risk of MRI and OB factors for evolution from RIS to MS in subjects included in the Argentinean MS registry (NCT03375177). Methods: RIS subjects were identified according ...
  • Acting centrally or peripherally: A renewed interest in the central nervous system penetration of disease-modifying drugs in multiple sclerosis 
    Correale, Jorge; Halfon, Mario Javier; Jack, Dominic; Rubstein, Adrián; Villa, Andrés (Elsevier, 2021-09-14)
    With the recent approval of cladribine tablets, siponimod and ozanimod, there has been a renewed interest into the extent to which these current generation disease-modifying therapies (DMTs) are able to cross into the ...
  • Adaptation and validation of a Spanish version of the treatment burden questionnaire in patients with multiple sclerosis 
    Ysrraelit, María Célica; Fiol, Marcela Paula; Vazquez Peña, Fernando; Vanotti, Sandra; Terrasa, Sergio Adrián; Viet-Thi, Tran; Montori, Victor M.; Correale, Jorge (BioMed Central, 2019-08-27)
    Background: The Treatment Burden Questionnaire (TBQ) is a self-reported measure of the effect of treatment workload on patient wellbeing. We sought to validate the TBQ in Spanish and use it to estimate the burden of treatment ...
  • Aggressive multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM 
    Kohler, Matías; Kohler, Eduardo; Vrech, Carlos; Pappolla, Agustín; Miguez, Jimena; Patrucco, Liliana; Correale, Jorge; Marrodán, Mariano; Gaitán, María Inés; Fiol, Marcela Paula; Negrotto, Laura; Ysrraelit, María Célica; Cristiano, Edgardo; Carrá, Adriana; Steinberg, Judith; Martinez, Alejandra D.; Curbelo, María Celeste; Cohen, Leila; Alonso, Ricardo; Garcea, Orlando (Elsevier, 2021-06-01)
    The objectives of the present study were to describe the frequency of aggressive multiple sclerosis (aMS) as well as to compare clinical and radiological characteristics in aMS and non-aMS patients included in RelevarEM ...
  • Are highly active and aggressive multiple sclerosis the same entity? 
    Correale, Jorge; Rush, Carolina A.; Barboza, Andrés G. (Frontiers Research Foundation, 2023-03-03)
    Resumen no disponible.
  • The Argentinean multiple sclerosis registry (RelevarEM): Methodological aspects and directions 
    Rojas, Juan Ignacio; Carrá, Adriana; Correale, Jorge; Cristiano, Edgardo; Fernandez Liguori, Nora; Alonso, Ricardo; Alvez Pinheiro, Amelia; Balbuena Aguirre, María Eugenia; Barboza, Andrés G.; Bestoso, Santiago; Blaya, Patricio A.; Burgos, Marcos; Cabrera, Lorena M.; Caride, Alejandro; Carnero Contentti, Edgar; Cohen, Leila; Curbelo, María Celeste; Deri, Norma; Divi, Pablo; Fiol, Marcela Paula; Fracaro, María Eugenia; Gaitán, María Inés; Hryb, Javier Pablo; Jacobo, Miguel; Knorre, Eduardo; Leguizamon, Felisa; Giunta, Diego Hernán; Serena, Marina Alonso; Doldan, María L.; de Lio, Guillermo F.; del V. Liwacki, Susana; López, Pablo Adrián; Luetic, Geraldine G.; Mainella, Carolina; Manzi, Ruben; Marrodán, Mariano; Martínez, Alejandra Diana; Míguez, Jimena S.; Negrotto, Laura; Nofal, Pedro G.; Parada Marcilla, Marcela; Pettinicchi, Juan Pablo; Silva, Berenice Anabel; Silva, Emanuel D.; Silveira, Facundo; Steinberg, Judith; Tavolini, Darío; Tizio, Santiago; Tkachuk, Verónica A.; Vazquez, Guido; Volman, Gabriel; Vrech, Carlos; Ysrraelit, María Célica; Zanga, Gisela; Garcea, Orlando; Patrucco, Liliana (Elsevier, 2019-05-15)
    Despite that different registries already exist in various countries in Europe and North America, no ongoing nationwide registry exists in Latin America (LATAM), a region where the disease behaves differently than in other ...
  • Argentinean recommendations on the identification of treatment failure in relapsing remitting multiple sclerosis patients 
    Cristiano, Edgardo; Alonso, Ricardo; Alvez Pinheiro, Amelia; Bacile, Elizabeth A.; Balbuena Aguirre, María Eugenia; Ballario, Carlos; Barboza, Andrés G.; Bestoso, Santiago; Burgos, Marcelo; Cáceres, Fernando; Carnero Contentti, Edgar; Carrá, Adriana; Crespo, Ernesto; Curbelo, María Celeste; Deri, Norma; Fernandez, Jorge; Fernandez Liguori, Nora; Fiol, Marcela Paula; Gaitán, María Inés; Garcea, Orlando; Giunta, Diego Hernán; Halfon, Mario Javier; Hryb, Javier Pablo; Jacobo, Miguel; Kohler, Eduardo; Linares, Ramiro; Luetic, Geraldine G.; Martínez, Alejandra Diana; Míguez, Jimena S.; Nofal, Pedro G.; Patrucco, Liliana; Piedrabuena, Raúl; Rojas, Juan Ignacio; Rotta Escalante, Roberto; Saladino, María Laura; Silva, Berenice Anabel; Sinay, Vladimiro; Steinberg, Judith; Tarulla, Adriana; Vétere, Santiago A.; Villa, Andrés; Vrech, Carlos; Ysrraelit, María Célica; Correale, Jorge (Elsevier, 2018-02-15)
    One of the biggest challenges in multiple sclerosis (MS) is the definition of treatment response/failure in order to optimize treatment decisions in affected patients. The objective of this consensus was to review how ...
  • Aspectos clínicos y demográficos de los pacientes con esclerosis múltiple secundaria progresiva en Argentina 
    Gaitán, María Inés; Marrodán, Mariano; Negrotto, Laura; Ysrraelit, María Célica; Miguez, Jimena; Alonso Serena, Marina; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Vrech, Carlos; Rojas, Juan Ignacio; Grupo de Trabajo Relevar EM (Fundación Revista Medicina (Buenos Aires), 2020)
    El objetivo del estudio fue evaluar los aspectos clínicos y demográficos de los pacientes con esclerosis múltiple (EM) secundaria progresiva (EMSP) en los pacientes incluidos en el Registro Argentino de EM (RelevarEM, ...
  • Autoimmune Astrocytopathy 
    Correale, Jorge; Gaitán, María Inés (Springer, 2019-08-14)
    Astrocytes are the most abundant and heterogeneous type of glial cell in the Central Nervous System. In addition to their role maintaining physiological conditions stable in the CNS, they are recognized as early and highly ...
  • Barriers to access and utilization of multiple sclerosis care services in a large cohort of Latin American patients 
    Carnero Contentti, Edgar; Giachello, Susana; Correale, Jorge (Sage, 2021-01)
    Background: Multiple sclerosis (MS), is an emergent disease in Latin America (LATAM), which raises substantial socioeconomic challenges to a region where most countries remain as economies in development. Objective: To ...
  • Bruton's tyrosine kinase inhibitors: a promising emerging treatment option for multiple sclerosis 
    Carnero Contentti, Edgar; Correale, Jorge (Taylor & Francis, 2020-12)
  • BTK inhibitors as potential therapies for multiple sclerosis 
    Correale, Jorge (Elsevier, 2021-08-19)
    Resumen no disponible
  • Clinical and demographic characteristics of male MS patients included in the national registry-RelevarEM. Does sex or phenotype make the difference in the association with poor prognosis? 
    Luetic, Geraldine G.; Menichini, María Laura; Vrech, Carlos; Pappolla, Agustín; Patrucco, Liliana; Cristiano, Edgardo; Marrodán, Mariano; Ysrraelit, María Célica; Fiol, Marcela Paula; Correale, Jorge; Cohen, Leila; Alonso, Ricardo; Silva, Berenice Anabel; Casas, Magdalena; Garcea, Orlando; Deri, Norma; Burgos, Marcos; Liwacki, Susana; Tkachuk, Verónica A.; Barboza, Andrés G. (Elsevier, 2021-11-17)
    Background In multiple sclerosis demographics there is a well-known female prevalence and male patients have been less specifically evaluated in clinical studies, though some clinical differences have been reported between ...
  • Clinical characteristics, course and prognosis of Multiple Sclerosis patients with epilepsy. A case control study: MS and epilepsy 
    Sánchez, M.; Marone, Abril; Silva, Walter H.; Marrodán, Mariano; Correale, Jorge (Elsevier, 2024-01-02)
    Background and purpose: Although more common than in the general population, seizures are an atypical manifestation of multiple sclerosis (MS) and their pathophysiology is not well understood. This study aims to examine ...
  • Clinical characterization of long-term multiple sclerosis (COLuMbus) patients in Argentina: A cross-sectional non-interventional study 
    Deri, Norma; Barboza, Andrés G.; Vrech, Carlos; Rey, Roberto; Burgos, Marcos; Fiol, Marcela Paula; Calvo Vildoso, Christian; Patrucco, Liliana; José, Gustavo; Aliberti, Paula; Chirico, Daniela; Federico, María B.; Seifer, Gustavo; Piedrabuena, Raúl (Elsevier, 2023-12-31)
    Background: Most Multiple Sclerosis (MS) clinical trials fail to assess the long-term effects of disease-modifying therapies (DMT) or disability. Methods: COLuMbus was a single-visit, cross-sectional study in Argentina ...
  • Clinical impact of gender and age at onset on disease trajectory in primary progressive multiple sclerosis patients 
    Camerlingo, Sebastián; Rubinstein, Fernando; Ysrraelit, María Célica; Correale, Jorge; Carnero Contentti, Edgar; Rojas, Juan Ignacio; Patrucco, Liliana; Del Valle Leguizamon, Felisa; Tkachuk, Verónica A.; Fernández Liguori, Nora; Cristiano, Edgardo; Mainella, Carolina; Zanga, Gisela; Carrá, Adriana; Marrodán, Mariano; Martínez, Alejandra Diana; Silva, Berenice Anabel; Alonso, Ricardo (Sage Publications, 2024-01-21)
    Background and objectives: Primary-progressive multiple sclerosis (PPMS) is characterized by gradual neurological deterioration without relapses. This study aimed to investigate the clinical impact of gender and age at ...
  • Clinically relevant increases in serum neurofilament light chain and glial fibrillary acidic protein in patients with Susac syndrome 
    Plantone, Domenico; Sabatelli, Eleonora; Locci, Sara; Marrodán, Mariano; Laakso, Sini M.; Mateen, Farrah J.; Feresiadou, Amalia; Buelens, Tom; Bianco, Assunta; Fiol, Marcela Paula; Correale, Jorge; Tienari, Pentti; Calabresi, Paolo; De Stefano, Nicola; Iorio, Raffaele (Wiley, 2023-06-19)
    Background and purpose: Serum levels of neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are promising neuro-axonal damage and astrocytic activation biomarkers. Susac syndrome (SS) is an ...
  • Colony-stimulating factor-1 receptor inhibition attenuates microgliosis and myelin loss but exacerbates neurodegeneration in the chronic cuprizone model 
    Wies Mancini, Victoria Sofía Berenice; Di Pietro, Anabella A.; de Olmos, Soledad; Silva Pinto, Pablo; Vence, Marianela; Marder, Mariel; Igaz, Lionel M.; Marcora, María Silvina; Pasquini, Juana María; Correale, Jorge; Pasquini, Laura Andrea (Oxford, 2022-03)
    Multiple sclerosis (MS), especially in its progressive phase, involves early axonal and neuronal damage resulting from a combination of inflammatory mediators, demyelination, and loss of trophic support. During progressive ...
  • Comorbidities in multiple sclerosis and their influence on the choice of treatment 
    Barboza, Andrés G.; Sinay, Vladimiro; Alonso, Ricardo; Carnero Contentti, Edgar; Hryb, Javier; Silva, Berenice Anabel; Tavolini, Darío; Ysrraelit, María Célica; Correale, Jorge (Revista de Neurología, 2024-03-16)
    Los estudios clínicos de tratamientos para personas con esclerosis múltiple (pEM) se realizan en poblaciones seleccionadas, que excluyen a pacientes que presenten comorbilidades o medicaciones concomitantes. Sin embargo, ...

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