Early-career researchers from low- and middle-income countries face systemic barriers to professional development and leadership growth. This article presents results from an initiative led by the World Young Leaders in ...

Background: Metabolic dysfunction-associated fatty liver disease (MAFLD) has multifactorial pathogenesis. Given its close relationship with dietary habits, and the need for improved geographical representation and sex ...

Introduction: Adipose tissue regulates metabolic homeostasis and serves as a reservoir for mesenchymal stem cells (MSCs), which differentiate into osteoblasts and adipocytes, balancing bone and lipid metabolism. Bone loss ...

Environmental exposure to paraquat (PQ), a widely used herbicide, has been associated with an increased risk of neurodegenerative diseases such as Parkinson's disease. However, species-specific limitations of traditional ...

Accurate cell type identification in single-cell RNA sequencing (scRNA-seq) datasets is essential for dissecting the tumor immune microenvironment (TIME) and optimizing immunotherapy strategies. Here, we present an annotation ...

Aims Whole blood RNA expression is modulated in response to signals from tissues, including the vessel wall. The primary objective of this study was to explore the ability of whole blood transcriptomes, analysed using ...

Background: Chronic ataxias, a complex group of over 300 diseases, pose significant diagnostic challenges because of their clinical and genetic heterogeneity. Here, we propose that artificial intelligence (AI) can aid in ...

Pulmonary and extrapulmonary manifestations have been reported following infection with SARS-CoV-2, the causative agent of COVID-19. The virus persists in multiple organs due to its tropism for various tissues, including ...

Resumen no disponible

Bone loss is a prevalent characteristic among people with HIV (PWH). We focused on mesenchymal stem cells (MSCs) and osteoblasts, examining their susceptibility to different HIV strains (R5- and X4-tropic) and the subsequent ...