Repositorio Institucional FLENI: Recent submissions

  • Chorea and Levodopa-Induced Dyskinesia in Corticobasal Syndrome: Two Case Reports with Pathological Insights and Literature Review 
    Medina Escobar, Alex; Rossi, Malco Damián; Richer, Maxime; Gautreau, Sylvia; Lang, Anthony E. (Wiley, 2025-05-11)
    Background: Corticobasal syndrome (CBS) is a rare, clinically heterogeneous form of atypical Parkinsonism. Hyperkinetic movements, aside from myoclonus and dystonia, have rarely been reported in CBS. Cases: We present ...
  • Capacity building in dementia research: insights from the World Young Leaders in Dementia 
    Morello-García, Florentina; Corvalán, Nicolás; Llibre-Guerra, Jorge; Arruabarrena, Micaela; Clarens, María Florencia; Keller, Greta; De Los Santos, Loana; Martin, María Eugenia; Schaffer Aguzzoli, Cristiano; Allegri, Ricardo Francisco; Amaral, Livia; Ardohain Cristalli, Carolina; Bellaver, Bruna; Ngozi Best, Merci; Bloomquist, Madeleine; Chen, Kevin; Surace, Ezequiel Ignacio; Wilks, Hannah; Zimmer, Eduardo; Crivelli, Lucía; Hernández, Micaela Anahí; Magrath Guimet, Nahuel (Wiley, 2025-12)
    Early-career researchers from low- and middle-income countries face systemic barriers to professional development and leadership growth. This article presents results from an initiative led by the World Young Leaders in ...
  • CADASIL Argentine Registry: Study Design and Preliminary Data 
    Ardohain Cristalli, Carolina Agata; Rosales, Julieta Soledad; Gonzalez, Fabio; Selvaggi, Valentin; Alonso, Julián Martín; López, Juan Ignacio; Aguilar, Martín Santiago; Kauffman, Marcelo; Saks, Danit G.; Allegri, Ricardo Francisco; Sevlever, Gustavo Emilio; Chaves, Hernán; Cristalli, Diana Olga; Calandri, Ismael Luis (Wiley, 2024)
    Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), the most common hereditary small vessel disease, leads to early-onset stroke and vascular cognitive ...
  • The Role of Basal Ganglia Theta Oscillations in Predicting the Onset of Levodopa-Induced Dyskinesias 
    Wilken, Miguel; Granda, Luna; Cruz, Ivonne; Rossi, Malco Damián; Cerquetti, Daniel; Merello, Marcelo (Wiley, 2025-10-11)
    Background: Levodopa-induced dyskinesias (LIDs) are an important burden for patients with Parkinson's disease (PD), yet their mechanisms remain incompletely understood. Objective: The objective of this study was to ...
  • Childhood and Adolescent Environmental Risk Factors for Multiple Sclerosis: A Systematic Review With Meta-Analysis 
    Vitturi, Bruno Kusznir; Cellerino, Maria; Boccia, Daniele; Leray, Emmanuelle; Correale, Jorge; Dobson, Ruth; van der Mei, Ingrid; Fujihara, Kazuo; Inglese, Matilde (Wiley, 2025-10-28)
    Background: We aimed to provide updated evidence from the current literature regarding pediatric environmental factors associated with the risk of developing multiple sclerosis (MS). Methods: Articles were searched in ...
  • SmartRehab: Enhancing Stroke Recovery through Automated Telerehabilitation (P7-14.011) 
    Velez, Faddi Saleh; Yeung, Elton; Bonin Pinto, Camila; Ling, Tsei Mei; Alet, Matías Javier; Carbonera, Leonardo; Ciopleias, Bogdan; khan, Abdul; Law, Zhe Kang; Lotlikar, Radhika; Liu, Roxanna; So, Adrian; Chan, Yin; Poon, Gloria; Boada Robayo, Laura; Rudyk, Demian; Kiper, Pawel; Yabluchanskiy, Andriy; Savitz, Sean; Luo, Louis (Lippincott Williams & Wilkins, 2025-04-07)
    Objective: We tested the SmartRehab efficacy, usability, and feasibility for stroke rehabilitation across seven countries. Background: Stroke is a major cause of disability worldwide. Timely and personalized rehabilitation ...
  • Clinical Validation of the SECONDs Tool for Evaluating Disorders of Consciousness in Argentina 
    Russo, María Julieta; Sampayo, María de la Paz; Arias, Paula; García, Vanina; Gambero, Yanina; Maiarú, Mariano; Deschle, Florencia; Pavón, Hernán (MDPI, 2025-10-07)
    Background: The Coma Recovery Scale-Revised (CRS-R) is the gold standard for diagnosing chronic disorders of consciousness (DoC); however, its clinical utility is limited by lengthy administration and the need for specialized ...
  • Thyrotropin Modulates Calcium Handling and Contractility in Adult Cardiac Myocytes 
    Sepúlveda, Marisa; Racioppi, Florencia; Burgos, Juan Ignacio; Murillo, Alexandra; Fernandez-Ruocco, Julieta; Gonano, Luis; Neiman, Gabriel; Miriuka, Santiago Gabriel; Fellet, Andrea; Casis, Oscar; Medei, Emiliano; Colareda, German; Vila Petroff, Martín (Elsevier, 2025-10-15)
    Hypothyroidism is an independent risk factor for cardiovascular disease and, if chronically sustained, leads to myocardial contractile dysfunction resulting in heart failure. However, the subcellular mechanisms underlying ...
  • Gender-specific associations between metabolic dysfunction-associated fatty liver disease with atherosclerosis, inflammation, and eating habits 
    Rodriguez-Granillo, Gaston A.; Poggio, Rosana; Rubilar, Alejandra B.; Garron-Arias, Sarah Y.; Solari, Claudia; La Greca, Alejandro; Luzzani, Carlos; Fontana, Lucia; Arnone, Carolina V.; Ingino, Carlos; Miriuka, Santiago Gabriel (Elsevier, 2025-11-11)
    Background: Metabolic dysfunction-associated fatty liver disease (MAFLD) has multifactorial pathogenesis. Given its close relationship with dietary habits, and the need for improved geographical representation and sex ...
  • Associations of lifestyle factors with amyloid pathology in persons without dementia 
    Oomens, Julie E.; Vos, Stephanie Jb; Maserejian, Nancy N.; Boada, Mercè; Didic, Mira; Engelborghs, Sebastiaan; Fladby, Tormod; van der Flier, Wiesje M.; Frisoni, Giovanni B.; Fröhlich, Lutz; Gill, Kiran Dip; Grimmer, Timo; Hort, Jakub; Allegri, Ricardo Francisco; Alzheimer's Disease Neuroimaging Initiative (ADNI); A4 Study group; Dominantly Inherited Alzheimer Network (DIAN); European Prevention of Alzheimer's Dementia (EPAD) consortium, Fundació ACE Healthy Brain Initiative (FACEHBI); Japan Alzheimer's Disease Neuroimaging Initiative (J-ADNI), Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease (KBASE); Presymptomatic Evaluation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) research group (Sage, 2025-11-13)
    BackgroundThe association between lifestyle factors and Alzheimer's disease (AD) pathophysiology remains incompletely understood.ObjectiveThe aim of this study was to assess the association of alcohol consumption, smoking ...
  • Valoración de la calidad del sueño en pacientes con artritis reumatoide, espondiloartritis y lupus eritematoso sistémico: estudio del noreste argentino 
    Ringer, Ariana; Antoniol, María Noelia; Aste, Nora; Benavente, Emilio Pablo Ignacio; Gallino, Josefina; Schmid, María Marcela; Mauri, Marianela Eliana; Seewald, Adriana; Paris, Úrsula Vanesa; Bravo, Maximiliano; Catay, Erika Roxana; Sattler, María Emilia; Góngora, Vanina; Finucci Curi, Pablo; Velozo, Edson Javier (Sociedad Argentina de Reumatología, 2025-05-29)
    Introducción: las patologías autoinmunes y sus tratamientos pueden relacionarse con la calidad del sueño. Objetivos: evaluar la calidad del sueño en pacientes con artritis reumatoide (AR), espondiloartritis (SpA) ...
  • Latin America Multidisciplinary Consensus Panel on Management of Severe Bleeding in the Anticoagulated Patient 
    Pontes-Neto, Octávio M.; Noble-Lugo, Alejandra; Montenegro Arenas, Ana Cristina; de Campos Guerra, Joao Carlos; Ceresetto, Jose Manuel; Rosales, Julieta Soledad; Colunga-Lozano, Luis Enrique; Meillon-Garcia, Luis Antonio; Vargas Tellez, Luis Eduardo; Dos Reis Rodrigues, Roseny; Gibler, W. Brian; Kreitzer, Natalie P. (Elsevier, 2025-05-05)
    Background: Bleeding is the most important complication associated with anticoagulants. Patients experiencing bleeding while on an anticoagulation require proper risk stratification, which involves careful assessment of ...
  • Efficacy and safety of Cladribine as a therapeutic option in multiple sclerosis patients over 50 years of age: A real-world study 
    Piedrabuena, María Agustina; Correale, Jorge; Silva, Berenice; Fiol, Marcela; Marrodán, Mariano; Zárate, María Agustina; Heriz, Alejandra; Ayerbe, Jeremías; Míguez, Jimena; Pita, Cecilia; Lázaro, Luciana; Casas, Magdalena; López, Pablo Adrián; Tkachuk, Verónica; Balbuena, María Eugenia; Nadur, Débora; Liwacki, Susana; Luetic, Geraldine; Burgos, Marcos; Ysrraelit, María Célica (Elsevier, 2025-11-15)
    Background: Despite an aging multiple sclerosis (MS) population, clinical outcomes and long-termeffects of disease-modifying therapies in patients aged ≥50 years remain under-studied. Objective: To compare the efficacy ...
  • Cannabidiol (CBD) as a novel inhibitor of HLA-G expression in human choriocarcinoma cell line (JEG-3) 
    Martínez, Kevin I.; Palma, María Belén; Sepúlveda, Fernando J.; Moavro, Damián E.; Carosella, Edgardo D.; García, Marcela N.; Riccillo, Fernando L. (Nature Publishing Group, 2025-11-13)
    Cannabinoids have emerged as promising agents in cancer research due to their antitumor properties. While their effects on tumor growth and survival are well documented, their influence on immune checkpoint regulation ...
  • Quantitative Assessment of Proprioceptive Force Perception in Parkinson’s Disease Using a Sensor-Based Grip Task 
    Martínez de Sucre, M. Nahuel; Bianchi, Gianfranco; Wilken, Miguel; Cruz Molina, Cecilia; Noel, Gabriel; Andrés, Daniela (Springer, 2025-10-16)
    Parkinson’s disease (PD) is characterized by progressive motor and sensorimotor deficits, including impairments in proprioception and grip force control. Despite their clinical relevance, these alterations are rarely ...
  • Introducing e-Motions: a novel intraoperative test for social cognition mapping. Triple validation in normative, schizophrenia, and autism spectrum disorder populations 
    Martín-Fernández, Jesús; Caballero-Estebaranz, Nayra; Félez, Esteban; Pérez Del Rosario, Pedro; Rodríguez Pulido, Francisco; Navarro-Peris, Natalia; Martínez, Fernando; Cervio, Andrés Eduardo; Martín-Monzón, Isabel (Springer, 2025-09-30)
    Background: Social cognition is essential for daily functioning, as it influences quality of life, return to work, and interpersonal communication. While schizophrenia and autism spectrum disorder (ASD) have been the ...
  • Therapeutic Plasma Exchange in Corticosteroid-Refractory Multiple Sclerosis Relapses: Mechanisms, Efficacy, and Integration into Clinical Practice 
    Marrodán, Mariano; Ysrraelit, María Célica; Correale, Jorge (MDPI, 2025-09-30)
    Therapeutic plasma exchange (TPE) is increasingly recognized as a critical escalation therapy for managing acute multiple sclerosis (MS) relapses refractory to high-dose corticosteroids. Neuropathological and clinical ...
  • A RoadMap for Neuropsychological Assessment of the Right Temporal Variant of Frontotemporal Dementia (rtvFTD): Case Studies and Practical Applications 
    De Los Santos, Loana; Morello García, Florentina; Ardohain Cristalli, Carolina Agata; Tabernero, María Eugenia; Clarens, María Florencia; Crivelli, Lucía; Magrath Guimet, Nahuel (Wiley, 2025)
    Background: The right temporal variant of frontotemporal dementia (rtvFTD) is a neurodegenerative condition characterized by progressive atrophy of the right anterior temporal lobe (rATL), significantly impairing ...
  • Anti-NMDAR encephalitis across the lifespan: Clinical, electrophysiological, and prognostic insights from a Latin American cohort 
    Marrodán, Mariano; Perez Arana, Carolina I.; Kirchner, Ricardo J.; Varela, Francisco José; Orzuza, Gabriela I.; Schteinschnaider, Ángeles; Chaderevian, Miriam G.; Vita, Cristina; Farez, Mauricio Franco; Correale, Jorge (Elsevier, 2025-12-15)
    Background and objectives: Anti-N-Methyl-d-aspartate receptor encephalitis (NMDARE) is the most prevalent autoimmune encephalitis, primarily affecting young females. Its clinical heterogeneity, particularly in underrepresented ...
  • Iron Deficiency in Drosophila melanogaster Glial Cells Impacts Behavior Through Altered Mitochondrial Dynamics 
    Marcora, María S.; Katz, Maximiliano J.; Galo, Azul; Bochicchio, Pablo; Bongiovanni, Vinicius; Bodín, Diego H.; Pagani, Mario R.; Correale, Jorge; Pasquini, María J. (Wiley, 2025-11-10)
    Iron deficiency (ID) is the most common micronutrient deficiency globally. ID in pre- and post-natal periods has been associated with impaired neurological development and altered behavior, which may persist despite iron ...

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