Repositorio Institucional FLENI: Recent submissions

  • Comparative Anatomical Assessment of the Contralateral Precaruncular Approach to the Supraoptic Triangle : A Cadaveric Study 
    Gago, Guilherme; Odeibat, Yousef; Monsalve, Martin; Côté, Martin; Champagne, Pierre-Olivier (Thieme, 2026-02-27)
    Background: The supraoptic triangle (SOT) is a bony-dural region located along the superior surface of the optic canal, corresponding to the base of the anterior clinoid process. It is bounded inferiorly by the optic nerve, ...
  • Vasculitis del sistema nervioso central en pacientes inmunocompetentes con criptococosis meníngea 
    Camporro, Julieta; Varela, Francisco; Yañez, Paulina; Bravo, Martín; Tomatis, Antonela; Mora, Andrea (Fundación Revista Medicina, 2025-09-05)
    La criptococosis meníngea (CM) es una infección micótica grave que puede presentarse en individuos inmunocompetentes. Su diagnóstico presenta difi cultades debido a su baja frecuencia y presentación clínica variable. Las ...
  • Trigeminal neuralgia 
    Bohórquez-Valderrama, Stephania; Santillán, María Elena; Corzo, Matías Sebastián; Buonanotte, Carlos Federico; Bonamico, Lucas Héctor (Brazilian Headache Society, 2025-12-31)
    Background Trigeminal neuralgia (TN) is a chronic neuropathic pain disorder characterized by recurrent, severe, unilateral facial pain in the distribution of one or more branches of the trigeminal nerve. Discussion Although ...
  • Toxina botulínica tipo A en el tratamiento preventivo de la migraña crónica: experiencia en un servicio de cefaleas de Argentina 
    Larripa, Natalia; Grandinetti, Mariela; Calvo, Daniela; Nagel, Vanesa; Goicochea, María Teresa (Fundación Revista Medicina, 1962, 2025-09-23)
    Introducción: La migraña crónica (MC) es una de las enfermedades neurológicas más discapacitantes, con un marcado impacto en la calidad de vida y en la utilización de recursos sanitarios. En Argentina, no existen datos ...
  • The ICN-UN Battery: A Machine Learning-Optimized Tool for Expeditious Alzheimer's Disease Diagnosis 
    Barceló, Ernesto; Romero, Duban; Allegri, Ricardo Francisco; Meza, Eliana; Mosquera-Heredia, María I.; Vidal, Oscar M.; Silvera-Redondo, Carlos; Arcos-Burgos, Mauricio; Garavito-Galofre, Pilar; Vélez, Jorge I. (MDPI AG, 2025-11-28)
    Background/Objectives: Alzheimer's disease (AD) accounts for ~70% of global dementia cases, with projections estimating 139 million affected individuals by 2050. This increasing burden highlights the urgent need for ...
  • Brucella abortus Infection Promotes Mesenchymal Stem Cell Differentiation Toward Adipogenesis, Enhancing the Proinflammatory Profile 
    Freiberger, Rosa Nicole; López, Cynthia Alicia Marcela; Palma, María Belén; Cevallos, Cintia; Sviercz, Franco Agustin; Jarmoluk, Patricio; García, Marcela Nilda; Quarleri, Jorge; Delpino, M. Victoria (MDPI AG, 2026-04-23)
    The most common complication of active brucellosis in humans is osteoarticular injury. In the bone marrow microenvironment, mesenchymal stem cells (MSCs) can differentiate into either adipocytes or osteoblasts, and this ...
  • Relative impact of multidomain lifestyle interventions on deficit accumulation frailty over 24 months in the U.S. POINTER trial 
    Espeland, Mark A.; Olson, Kay Loni; Tangney, Christy C.; Gitelman, Darren R.; Cleveland, Maryjo L.; Thro, Amber A.; Demesie, Yitbarek N.; Snyder, Heather M.; Whitmer, Rachel A.; Desai, Pankaja; Alam, Rifat; Crivelli, Lucía; Holland, Thomas M.; Preissle, Olivia; Raman, Rema; York, Michele K.; Baker, Laura; U.S. POINTER Study Group (Gerontological Society of America by Oxford University Press, 2026-05)
    Background: Multidomain lifestyle interventions hold promise as approaches to slow aging. Deficit accumulation frailty indices (FIs) are increasingly used to capture aging processes. Frailty is highly associated with ...
  • Delphi consensus guidelines for the use of striatal dopaminergic imaging and cardiac metaiodobenzylguanidine (MIBG) scintigraphy for the diagnosis of dementia and mild cognitive impairment with Lewy bodies 
    Donaghy, Paul C.; Greenfinch, Gemma; Petrides, George; Kane, Joseph; Verberne, Hein J.; Taylor, John-Paul; O'Brien, John T.; Thomas, Alan J.; DLB Indicative Imaging Biomarker Study Group (Wiley on behalf of the Alzheimer's Association, 2026-03-04)
    Introduction: The aim of this Delphi process was to develop consensus guidelines to support the effective use of striatal dopaminergic imaging and cardiac metaiodobenzylguanidine (MIBG) scintigraphy in the diagnosis of ...
  • Selective Dorsal Rhizotomy for the Treatment of Spasticity Associated with HIV Encephalopathy (Hive) in 15 Pediatric Patients 
    Villamil, Facundo; Nazar, Ricardo; Ford, Fernando; Duffy, Clara; Mantese, Beatriz (Fundación CENIT, 2025-12-18)
    Introduction: Vertical transmission of HIV has decreased in developed countries but remains prevalent in developing nations. HIV-associated encephalopathy (HIVE) leads to severe neurological sequelae, including spasticity. ...
  • Chapter 21 - Role of cerebellum in Parkinson's disease symptoms 
    Varani, Andrés Pablo; Bagliani, María Camila; Rossi, Malco Damián (Elsevier, 2025-12-11)
    Parkinson's disease is characterized by a variety of motor and non-motor symptoms that arise from different regions of the central nervous system. Growing evidence indicates that pathological alterations in Parkinson's ...
  • Rizotomía Dorsal Selectiva: Análisis de dos Técnicas de Sección de Raíces Dorsales Sensitivas 
    Basilotta, Yamila; Mantese, Beatriz (Fundación CENIT, 2025-11-18)
    Introducción: La rizotomía dorsal selectiva (RDS) es una cirugía irreversible, cada vez más utilizada para tratar los trastornos de la marcha en niños con encefalopatía crónica no progresiva, mediante la reducción de la ...
  • Persistent post‑craniotomy headache: a narrative review 
    Alarcon-Ruiz, Christoper A.; Goicochea, María Teresa (Brazilian Headache Society, 2025-12-31)
    Persistent post-craniotomy headache (PPCH) is a frequent yet underrecognized complication of cranial surgery, often leading to long-term disability and impaired quality of life. Defined as a headache developing within seven ...
  • Longitudinal Phenotypic Trajectories in GNAO1-Related Disorders : Defining Disease Progression and Clinical Profiles 
    Domínguez-Carral, Jana; Domínguez Cobo, Ana María; Balsells, Sol; Aguilar Ros, Anna; Chang, Chu-Ting; Ludlam, William Grant; Yang, Kathryn; Bernardi, Katerina; Salazar Villacorta, Ainara; Di Pisa, Veronica; Lamagrande Casanova, Nuria; González Alguacil, Elena; De la Casa Fages, Beatriz; Chinigioli, Micaela; Okumura, Akihisa; Rodríguez, Josefina; Agarwal, Ayush; Muñoz Chesta, Daniela; Reynoso Osnayo, Carolina; Lin, Amy (Wiley-Liss, 2026-07)
    Objective: Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first ...
  • Eye tracking as a diagnostic tool in Alzheimer's disease, mild cognitive impairment, and related dementias: a systematic review 
    Verón, Gustavo Luis; Juantorena, Gustavo Ezequiel; Keller, Greta; Crivelli, Lucía; Kamienkowski, Juan Esteban (Wiley, 2025-12-30)
    Alzheimer's disease (AD) pathology begins years before symptoms emerge, making early detection essential. Eye tracking offers a rapid, non-invasive means of identifying early cognitive decline through oculomotor disturbances. ...
  • 15 years of longitudinal genetic, clinical, cognitive, imaging, and biochemical measures in DIAN 
    Daniels, Alisha; McDade, Eric; Llibre Guerra, Jorge J.; Dominantly Inherited Alzheimer Network; Xiong, Chengjie; Perrin, Richard J.; Ibañez, Laura; Supnet Bell, Charlene; Cruchaga, Carlos; Goate, Alison M.; Renton, Alan E.; Benzinger, Tammie L.S.; Gordon, Brian A.; Hassenstab, Jason; Karch, Celeste M.; Levey, Allan I.; Morris, John C.; Buckles, Virginia; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis (Nature Publishing Group UK, 2026-02-16)
    The Dominantly Inherited Alzheimer Network Observational Study (DIAN Obs) is a longitudinal, global cohort study investigating brain aging and autosomal dominant Alzheimer's disease (ADAD), a rare monogenic form of Alzheimer's ...
  • Scientific knowledge about dementia : From the Global South to the world 
    Daly, Timothy; López Barrenechea, Ignacio; Vergara, Paulina; Arshad, Faheem; Paplikar, Avanthi; Chaudhuri, Aparajita Ray; Crivelli, Lucía; Ibañez, Agustín; Alladi, Suvarna; Slachevsky, Andrea (John Wiley & Sons, Ltd., 2026-03)
    Most people with dementia live in low- and middle-income countries (LMICs), but scientific knowledge about dementia is dominated by Global North perspectives. This interdisciplinary article combines expertise from Latin ...
  • Silk vista baby versus pipeline embolization device for unruptured distal anterior cerebral artery aneurysms : A multicenter propensity-weighted comparative study 
    Da Ros, Valerio; Frédéric Clarençon; Dmytriw, Adam A.; Jabbour, Pascal; Psychogios, Marios; Sporns, Peter; Puri, Ajit S.; Hassan, Ameer E.; Algin, Oktay; Möhlenbruch, Markus A.; Bergui, Mauro; Goren, Oded; Boulouis, Gregoire; Morimoto, Takeshi; Pop, Raoul; Ho, Joanna Wk; Pujol Lereis, Virginia Andrea; Cooper, Jared; Salsano, Giancarlo; CRETA investigators (Masson, 2026-06)
    Background: Flow diversion is effective for unruptured distal anterior cerebral artery (DACA) aneurysms, yet comparative data between the Silk Vista Baby (SVB) and Pipeline Embolization Device (PED) in this challenging ...
  • Bridging Science and Care: 14 Years of Genetic and Biomarker Research in Neurodegenerative Diseases at an Argentine Memory Clinic 
    Surace, Ezequiel Ignacio; Romorini, Leonardo; Marazita, Mariela Claudia; Clas, Giulia Solange; Massazza, Victoria; Alvarez, María Florencia; Avendaño, Daniel; Itzcovich, Tatiana; Martinetto, Horacio (Wiley, 2025-12-24)
    Understanding the biological and genetic landscape of neurodegenerative diseases in diverse populations deepens our insight into complex pathophysiological mechanisms. Our laboratory, established 14 years ago in Buenos ...
  • Dementia screening protocol for primary care in South America : a Delphi consensus study 
    Custodio, Belen; Montesinos, Rosa; Caramelli, Paulo; Calandri, Ismael Luis; Dozzi Brucki, Sonia María; Suemoto, Claudia Kimie; Allegri, Ricardo Francisco; Slachevsky, Andrea; Parodi, Jose F.; Morsch, Patricia; Willets, Clarissa; Cuba Fuentes, María Sofía; Custodio, Nilton (Frontiers Editorial Office, 2026-04-08)
    Introduction: Rapid population aging in South America (SA) highlights the need for effective dementia detection strategies. Primary care is essential for early identification, yet no shared, regionally contextualized ...
  • Novel GNAO1 variant in α-helical domain reveals alternative mechanism of disease 
    Ludlam, William Grant; Domínguez-Carral, Jana; Schteinschnaider, Ángeles; Martemyanov, Kirill A.; Ortigoza-Escobar, Juan Darío (Elsevier, 2025-10-21)
    No abstract available.