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Auflistung Neurología nach Autor "Schultz, Stephanie A."

Auflistung Neurología nach Autor "Schultz, Stephanie A."

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  • AD-causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains 
    Schultz, Stephanie A.; Allegri, Ricardo Francisco; Schultz, Aaron P.; Goate, Alison M.; Levey, Allan I.; Fagan, Anne M.; Hanseeuw, Bernard J.; Koeppe, Robert A.; Gordon, Brian A.; Cruchaga, Carlos; Karch, Celeste M.; Chen, Charles D.; Xiong, Chengjie; Jack Jr, Clifford R.; Fitzpatrick, Colleen D.; McDade, Eric; Chui, Helena C.; Mori, Hiroshi; Lee, Jae-Hong; Noble, James M. (Wiley, 2022-12)
    Background Rates of cognitive and biomarker change in Autosomal Dominant Alzheimer disease (ADAD) vary substantially across individuals. Prior cross-sectional work suggests that the location of the pathogenic variant ...
  • Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease 
    Millar, Peter R.; Gordon, Brian A.; Wisch, Julie K.; Schultz, Stephanie A.; Benzinger, Tammie L.S.; Cruchaga, Carlos; Hassenstab, Jason; Ibanez, Laura; Karch, Celeste M.; Llibre Guerra, Jorge J.; Morris, John C.; Perrin, Richard J.; Supnet Bell, Charlene; Xiong, Chengjie; Allegri, Ricardo Francisco; Berman, Sarah B.; Chhatwal, Jasmeer P.; Chrem Méndez, Patricio Alexis; Day, Gregory S.; Dominantly Inherited Alzheimer Network (BioMed Central, 2023-12-19)
    Background: "Brain-predicted age" estimates biological age from complex, nonlinear features in neuroimaging scans. The brain age gap (BAG) between predicted and chronological age is elevated in sporadic Alzheimer disease ...
  • Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease 
    Shirzadi, Zahra; Schultz, Stephanie A.; Yau, Wai-Ying W.; Joseph-Mathurin, Nelly; Fitzpatrick, Colleen D.; Levin, Raina; Kantarci, Kejal; Preboske, Gregory M.; Jack Jr, Clifford R.; Farlow, Martin R.; Hassenstab, Jason; Jucker, Mathias; Morris, John C.; Xiong, Chengjie; Karch, Celeste M.; Levey, Allan I.; Gordon, Brian A.; Schofield, Peter R.; Allegri, Ricardo Francisco; Dominantly Inherited Alzheimer Network; Alzheimer’s Disease Neuroimaging Initiative (American Medical Association, 2023-12-01)
    Importance: Increased white matter hyperintensity (WMH) volume is a common magnetic resonance imaging (MRI) finding in both autosomal dominant Alzheimer disease (ADAD) and late-onset Alzheimer disease (LOAD), but it remains ...
  • Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease 
    Preische, Oliver; Schultz, Stephanie A.; Apel, Anja; Kuhle, Jens; Kaeser, Stephan A.; Barro, Christian; Gräber, Susanne; Kuder-Buletta, Elke; LaFougere, Christian; Laske, Christoph; Vöglein, Jonathan; Levin, Johannes; Masters, Colin L.; Martins, Ralph N.; Schofield, Peter R.; Rossor, Martin N.; Dominantly Inherited Alzheimer Network (Nature Publishing Group, 2019-01-21)
    Neurofilament light chain (NfL) is a promising fluid biomarker of disease progression for various cerebral proteopathies. Here we leverage the unique characteristics of the Dominantly Inherited Alzheimer Network and ...

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