Browsing Neurología by Author "Saravia, Flavia"

Now showing items 1-3 of 3

Diabetic patients treated with metformin during early stages of Alzheimer's disease show a better integral performance: data from ADNI study

Pomilio, Carlos; González Pérez, Nicolás; Calandri, Ismael Luis; Crivelli, Lucía; Allegri, Ricardo Francisco; ADNI Alzheimer’s Disease Neuroimaging Initiative; Sevlever, Gustavo Emilio; Saravia, Flavia (Springer International Publishing, 2022-06)

We evaluated the effect of the antidiabetic drug metformin on patients enrolled in the ADNI study considering patients with mild cognitive impairment (MCI) due to Alzheimer's disease (AD). Employing data from this observational ...
Loss of Direct Vascular Contact to Astrocytes in the Hippocampus as an Initial Event in Alzheimer's Disease. Evidence from Patients, In Vivo and In Vitro Experimental Models

Pomilio, Carlos; Presa, Jessica; Oses, Camila; Vinuesa, Ángeles; Bentivegna, Melisa; Gregosa, Amal; Riudavets, Miguel; Sevlever, Gustavo Emilio; Galvan, V.; Levi, Valeria; Beauquis, Juan; Saravia, Flavia (Humana Press, 2024-01-03)

Alzheimer's disease (AD) is characterized by the accumulation of aggregated amyloid peptides in the brain parenchyma and within the walls of cerebral vessels. The hippocampus-a complex brain structure with a pivotal role ...
Microglial autophagy is impaired by prolonged exposure to β-amyloid peptides: evidence from experimental models and Alzheimer's disease patients

Pomilio, Carlos; Gorojod, Roxana M.; Riudavets, Miguel; Vinuesa, Ángeles; Presa, Jessica; Gregosa, Amal; Bentivegna, Melisa; Alaimo, Agustina; Porte Alcon, Soledad; Sevlever, Gustavo Emilio; Kotler, Mónica L.; Beauquis, Juan; Saravia, Flavia (Springer, 2020-01-23)

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the presence of misfolded proteins, amyloid-β (Aβ) aggregates, and neuroinflammation in the brain. Microglial cells are key players in ...

Browsing Neurología by Author "Saravia, Flavia"

Browsing Neurología by Author "Saravia, Flavia"

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