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ListarNeurología por tema "Líquido Cefalorraquídeo"

ListarNeurología por tema "Líquido Cefalorraquídeo"

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  • Acting centrally or peripherally: A renewed interest in the central nervous system penetration of disease-modifying drugs in multiple sclerosis 
    Correale, Jorge; Halfon, Mario Javier; Jack, Dominic; Rubstein, Adrián; Villa, Andrés (Elsevier, 2021-09-14)
    With the recent approval of cladribine tablets, siponimod and ozanimod, there has been a renewed interest into the extent to which these current generation disease-modifying therapies (DMTs) are able to cross into the ...
  • Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease 
    Llibre Guerra, Jorge J.; Li, H; Schindler, Suzanne E.; Gordon, Brian A.; Fagan, Anne M.; Morris, John C.; Benzinger, Tammie L.S.; Hassenstab, Jason; Wang, Guoquiao; Allegri, Ricardo Francisco; Berman, Sarah B.; Chhatwal, Jasmeer P.; Farlow, Martin R.; Holtzman, David M.; Jucker, Mathias; Levin, Johannes; Noble, James M.; Salloway, Stephen; Schofield, Peter R.; Karch, Celeste M.; Fox, Nick C.; Xiong, Chengjie; Bateman, Randall J.; McDade, Eric (American Medical Association, 2019-12-02)
    The amyloid/tau/neurodegeneration (A/T/N) framework uses cerebrospinal fluid (CSF) levels of total tau (tTau) as a marker of neurodegeneration and CSF levels of phosphorylated tau 181 (pTau181) as a marker of tau tangles. ...
  • CSF Findings in Relation to Clinical Characteristics, Subtype, and Disease Course in Patients With Guillain-Barré Syndrome 
    Al-Hakem, Helle; Doets, Alex Y.; Stino, Amro Maher; Zivkovic, Sasha A.; Andersen, Henning; Willison, Hugh J.; Cornblath, David R.; Gorson, Kenneth C.; Islam, Zhahirul; Mohammad, Quazi Deen; Sindrup, Soren H.; Kusunoki, Susumu; Davidson, Amy; Casasnovas, Carlos; Bateman, Kathleen J.; Miller, James A. L.; van den Berg, Bianca; Verboon, Christine; Roodbol, Joyce; Barroso, Fabio Adrián (Lippincott Williams & Wilkins, 2023-04-19)
    Background and Objectives To investigate CSF findings in relation to clinical and electrodiagnostic subtypes, severity, and outcome of Guillain-Barré syndrome (GBS) based on 1,500 patients in the International GBS Outcome ...
  • Mucosal associated invariant T cell features and TCR repertoire characteristics during the course of Multiple Sclerosis 
    Carnero Contentti, Edgar; Farez, Mauricio Franco; Correale, Jorge (Frontiers Research Foundation, 2019-10-31)
    Objective: To investigate the frequency, phenotype, function and longitudinal repertoire of Mucosal-associated invariant T (MAIT) cells in relapsing remitting (RRMS) and primary progressive MS (PPMS) patients Methods: ...
  • Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid 
    Drieu, Antoine; Du, Siling; Storck, Steffen E.; Rustenhoven, Justin; Papadopoulos, Zachary; Dykstra, Taitea; Zhong, Fenghe; Kim, Kyungdeok; Blackburn, Susan; Mamuladze, Tornike; Harari, Oscar; Karch, Celeste M.; Bateman, Randall J.; Perrin, Richard J.; Farlow, Martin R.; Chhatwal, Jasmeer; Dominantly Inherited Alzheimer Network; Hu, Song; Randolph, Gwendalyn J.; Allegri, Ricardo Francisco (Nature Publishing Group, 2022-11)
    Macrophages are important players in the maintenance of tissue homeostasis1. Perivascular and leptomeningeal macrophages reside near the central nervous system (CNS) parenchyma2, and their role in CNS physiology has not ...

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