Neurología: Envíos recientes

  • Emerging Trends in Functional Movement Disorders Consultations and the Impact of a Major Life Event 
    Marín-Medina, Daniel S.; Lopez, Gala; Rossi, Malco Damián; Merello, Marcelo (Wiley, 2025-09-03)
    Background: Awareness and major external events can contribute to the number of FMD cases. Objective: To analyze trends in new Functional Movement Disorders (FMD) consultations and the impact of the COVID-19 ...
  • Young adults with ischemic stroke in Argentina: A national multicenter retrospective registry analysis (JACARANDA) 
    Gonzalez, Fabio; López, Juan I.; Tamagnini, Flavia; Bonardo, Pablo; Cotti, Norberto; Zavattieri, Agustina; Carobolante, Luciana; Arias, Carlos A .; Acosta, Maria V.; Balian, Natalia; Armaretti, Marianela L.; Mena, Ignacio A.; Gonzalez, Leonardo; Lepera, Sandra; Claverie, Santiago; Monclá, Tomas D.; Ureña, Brain C.; Apaza, Patricio I.; Farcy, Nicole; Alet, Matías Javier (Sage, 2025-09-04)
    Background: Young adults account for up to 15% of all ischemic strokes, yet data from Latin America remain scarce. Understanding their clinical profile and outcomes is essential to inform targeted interventions and public ...
  • New landscape of the diagnosis of Alzheimer's disease 
    Frisoni, Giovanni B.; Hansson, Oskar; Nichols, Emma; Garibotto, Valentina; Schindler, Suzanne E.; van der Flier, Wiesje M.; Jessen, Frank; Villain, Nicolas; Arenaza-Urquijo, Eider M.; Crivelli, Lucia; Fortea, Juan; Grinberg, Lea T.; Ismail, Zahinoor; Minoshima, Satoshi; Ossenkoppele, Rik; Zetterberg, Henrik; Petersen, Ronald C.; Dubois, Bruno (Elsevier, 2025-09-22)
    Alzheimer's disease involves a drastic departure from the cognitive, functional, and behavioural trajectory of normal ageing, and is both a dreaded and highly prevalent cause of disability to individuals, and a leading ...
  • A journey through genetic movement disorders caused by non-coding repeat expansions 
    Pinheiro Camurugy da Hora, Raphael; Rossi, Malco Damián; Rebelo Procaci, Victor; Yoshinaga Tonholo Silva, Thiago; Alves Corazza, Luiza; Novis, Luiz Eduardo; Barsottini, Orlando G.; Pedroso, José Luiz (Elsevier, 2025-07-21)
    Nucleotide repeat expansions are a key genetic mechanism underlying various neurological disorders, especially in movement disorders. While many expansion-related conditions are caused by variants in coding regions, an ...
  • The immunological role of oligodendrocytes: beyond myelin maintenance 
    Pasquini, Juana M.; Correale, Jorge (Oxford University Press on behalf of the British Society for Immunology, 2025-04-28)
    Oligodendrocytes (OGDs) are well-established cells in the central nervous system (CNS), primarily recognized for their role in myelination. However, emerging evidence suggests intrinsic differences among OGDs that may lead ...
  • Implementing Acute Stroke Services in Sub-Saharan Africa: Steps, Progress, and Perspectives from the Tanzania Stroke Project 
    Matuja, Sarah Shali; Tunkl, Christine; Roushdy, Tamer; Li, Linxin; Ouyang, Menglu; Saleh Velez, Faddi G.; Gebrewold, Meron; Minhas, Jatinder S.; Law, Zhe Kang; Katsanos, Aristeidis H.; Ullberg, Teresa; Mosconi, Maria Giulia; Khan, Maria; Alet, Matías Javier; Lotlikar, Radhika; Richardson, Alicia; Ciopleias, Bogdan; Heldner, Mirjam R.; Zuurbier, Susanna Maria; Ramage, Emily (Karger, 2025-04-23)
    Introduction: Stroke is a leading cause of morbidity and mortality globally, with Africa bearing a disproportionately high burden of poor outcomes. In sub-Saharan Africa, acute stroke care remains inconsistent, with organized ...
  • Cognitive and physical activities are associated with cognitive resilience in a memory clinic cohort 
    Bocancea, Diana I.; van Loenhoud, Anna C.; Kuijper, Bart; Calandri, Ismael Luis; Groot, Colin; Venkatraghavan, Vikram; de Boer, Casper; Ten Kate, Mara; Trieu, Calvin; Teunissen, Charlotte E.; van de Giessen, Elsmarieke; Leeuwis, Anna E.; Schlueter, Lisa-Marie; van Harten, Argonde C.; Pijnenburg, Yolande A. L.; Barkhof, Frederik; van der Flier, Wiesje M.; Ossenkoppele, Rik (Oxford University Press, 2025-09-06)
    Lifestyle factors such as participation in cognitively stimulating activities and physical activity are hypothesized to foster neural connections and enhance resilience, thereby attenuating cognitive loss in the context ...
  • Cross-Sectional FDG in Down Syndrome and Autosomal Dominant Alzheimer's Disease 
    Abdelmoity, Omar; Wisch, Julie K.; Kennedy, James T.; Goyal, Manu; Vlassenko, Andrei; Flores, Shaney; Handen, Benjamin L.; Head, Elizabeth; Keator, David; Rafii, Michael S.; Lao, Patrick; Lai, Florence; Rosas, H. Diana; Hartley, Sigan L.; Zaman, Shahid; Brickman, Adam M.; Tudorascu, Dana; Lee, Joseph H.; Allegri, Ricardo Francisco; Alzheimer's Biomarker Consortium‐Down Syndrome and the Dominantly Inherited Alzheimer Network (Wiley, 2025-09-22)
    Objectives: Directly compare the brain glucose patterns seen with [F-18] fluorodeoxyglucose (FDG) positron emission tomography (PET) between 2 genetically determined forms of Alzheimer's disease: Down syndrome (DS) and ...
  • Factors for Rituximab Refractoriness in AQP4-IgG+ NMOSD: A Cohort Study 
    Marrodán, Mariano; Piedrabuena, María Agustina; Zárate, María Agustina; Rodríguez Murúa, Sofía; Surace, Ezequiel Ignacio; Farez, Mauricio Franco; Fiol, Marcela Paula; Ysrraelit, María Célica; Correale, Jorge (Wiley Periodicals, 2025-08)
    Objective: Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin-4 antibodies (AQP4-IgG). Rituximab, a CD20+ B-cell depleting ...
  • Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome 
    Fissolo, Nicolás; Schaedelin, Sabine; Villar, Luisa M.; Lünemann, Jan D.; Correale, Jorge; Rejdak, Konrad; Schwab, Nicholas; Vilaseca, Andreu; Held, Friederike; García-Merino, Antonio; Bittner, Stefan; Trojano, María; Furlan, Roberto; Tumani, Hayrettin; Pérez-Miralles, Francisco; Rosenstein, Igal; Galimberti, Daniela; Álvarez-Bravo, Gary; Thouvenot, Eric; Llufriu, Sara (American Medical Associatio, 2025-07-01)
    Importance: Understanding the risk factors for symptom development will allow clinicians to stratify people with radiologically isolated syndrome (pwRIS) more effectively and tailor their management strategies accordingl ...
  • Infusiones de ketamina a dosis subanestésicas en la depresión mayor resistente al tratamiento: protocolo de aplicación en un hospital público de Argentina 
    Dines, Micaela; Bulacia, Adriana; Bamondez, Paloma; Vega, Irene Luis; Montenegro, Micaela; Díaz, Pablo Germán; Oyhamburu, Paula; Ramos, Ana Laura; Ambrosio, Florencia; Vázquez, Gustavo; Pereyra, Monica; Pereyra, Hugo; Cichello, Cynthia; Ríos Merino, Laura Natalia (Polemos, 2025-07-10)
    La depresión mayor resistente al tratamiento (DMRT) representa un desafío significativo en psiquiatría, dada la limitada respuesta a las terapias convencionales. La ketamina endovenosa (EV) a dosis subanestésicas ha emergido ...
  • Peer Reviewing a Case-Based Manuscript in Movement Disorders Neurology 
    Di Luca, Daniel G.; Prasad, Shweta; Kirby, Alana; Merello, Marcelo; Bhatia, Kailash P.; Goetz, Christopher (Wiley, 2025-05-05)
  • Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease 
    Chen, Charles D.; Franklin, Erin E.; Li, Yan; Joseph-Mathurin, Nelly; Burns, Aime L.; Hobbs, Diana A.; McCullough, Austin A.; Schultz, Stephanie A.; Xion, Chengjie; Wang, Guoqiao; Masellis, Mario; Robin Hsiung, Ging-Yuek; Gauthier, Serge; Berman, Sarah B.; Roberson, Erik D.; Honig, Lawrence S.; Clarnette, Roger; Allegri, Ricardo Francisco; DIAN-TU Study Team; DIAN-Obs Study Team (Springer Verlag, 2025-06-03)
    Clinical trials of anti-amyloid-β (Aβ) monoclonal antibodies in Alzheimer disease (AD) infer target engagement from Aβ positron emission tomography (PET) and/or fluid biomarkers such as cerebrospinal fluid (CSF) Aβ42/40. ...
  • Embolización Selectiva como tratamiento de la capsulitis adhesiva. Reporte de un caso 
    Bertoni, Hernán Gabriel; Rosado, Martín; Cavallo, Jorge (Sociedad Argentina de Reumatología, 2025-03-29)
    La capsulitis adhesiva constituye una patología del hombro que genera rigidez y restricción dolorosa al movimiento activo y pasivo de esta articulación. Es habitual su evolución crónica, generando limitaciones funcionales ...
  • Reevaluating triptan contraindications: A follow-up survey among Latin American neurologists 
    Bancalari, Ernesto; Robblee, Jennifer; Goicochea, María Teresa; Muñoz, Joe; Peres, Mario F.P.; Velez, Karina (Sage, 2025-06-04)
    ObjectiveSurvey Latin American (LATAM) neurologists on their comfort with prescribing triptans in the setting of common contraindications. BackgroundTriptans are associated with multiple contraindications due to 5-HT1B-mediated ...
  • Prospective longitudinal cohort of Argentinean patients with progressive supranuclear palsy and corticobasal syndrome: A platform for epidemiological and translational research 
    Ángel, María José; Mizraji, Gabril F.; Gómez-Arévalo, Gonzalo; Garcia, Silvia; González-Toledo, María Eugenia; Avale, Elena; Paez-Paz, Indiana; Falzone, Tomás; Holubiec, Mariana; Peralta, María C.; Castano, Federico; Sevlever, Gustavo Emilio; Mezmezian, Mónica Beatriz; Marras, Connie; Gershanik, Oscar; Chade, Anabel; Pardo, Carolina; Rellan, Florencia; Campastri, Ana; Couto, Blas (Elsevier, 2025-05-15)
    Background: Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are neurodegenerative disorders with disabling postural instability, falls and cognitive impairment associated with 4-repeat tau protein ...
  • Development of early progression independent of relapse activity significantly impacts on disability accumulation in patients with multiple sclerosis 
    Zárate, María Agustina; Marrodán, Mariano; Piedrabuena, María Agustina; Fiol, Marcela Paula; Ysrraelit, María Célica; Correale, Jorge (Elsevier, 2025-05-14)
    Background: Disability accumulation in multiple sclerosis (MS) is driven by relapse-associated worsening (RAW) and progression independent of relapse activity (PIRA). Early PIRA (EP), occurring within five years of disease ...
  • Dementia research in low-income and middle-income countries - a view from Latin America 
    Allegri, Ricardo Francisco (Nature, 2025-07-29)
    Dementia research, and research in general, has historically been scarce in low-income and middle-income countries (LMICs). However, a high burden of dementia is faced by these regions, with a higher prevalence compared ...
  • Hereditary Ataxias in Argentina 
    Rossi, Malco Damián; Merello, Marcelo (Springer, 2025-04-08)
    Hereditary or genetic ataxias are hundreds of disorders characterized by large phenotypic, genetic, and epidemiological heterogeneity. In Argentina, 35 genetic ataxias have been identified, with SCA1 (ATX-ATXN1), SCA2 ...
  • Association of the Timing and Type of Acute Symptomatic Seizures With Poststroke Epilepsy and Mortality 
    Schubert, Kai Michael; Zieglgänsberger, Dominik; Bicciato, Giulio; Abraira, Laura; Santamarina, Estevo; Álvarez-Sabín, José; Ferreira-Atuesta, Carolina; Katan, Mira; Sinka, Lucia; Terziev, Robert; Deligas, Nico; Erdélyi-Canavese, Barbara; Felbecker, Ansgar; Siebel, Philip; Winklehner, Michael; von Oertzen, Tim J.; Wagner, Judith N.; Gigli, Gian Luigi; Nilo, Annacarmen; Alet, Matías Javier (Lippincott Williams & Wilkins, 2025-07)
    Background: Acute symptomatic seizures (ASyS) increase the risk of epilepsy and mortality after a stroke. The impact of the timing and type of ASyS remains unclear. Methods: This multicenter cohort study included data ...

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