DSpace Repositorium (Manakin basiert)

Axial Postural Abnormalities in Parkinsonism: Gaps in Predictors, Pathophysiology, and Management

Zur Kurzanzeige

dc.contributor.author Geroin, Christian
dc.contributor.author Artusi, Carlo Alberto
dc.contributor.author Nonnekes, Jorik
dc.contributor.author Aquino, Camila
dc.contributor.author Garg, Divyani
dc.contributor.author Dale, Marian L.
dc.contributor.author Schlosser, Darbe
dc.contributor.author Lai, Yijie
dc.contributor.author Al-Wardat, Mohammad
dc.contributor.author Salari, Mehri
dc.contributor.author Wolke, Robin
dc.contributor.author Tsinda Labou, Valery
dc.contributor.author Imbalzano, Gabriele
dc.contributor.author Camozzi, Serena
dc.contributor.author Merello, Marcelo
dc.contributor.author Bloem, Bastiaan R.
dc.contributor.author Capato, Tamine
dc.contributor.author Djaldetti, Ruth
dc.contributor.author Doherty, Karen
dc.contributor.author International Parkinson and Movement Disorders Society Task Force on Postural Abnormalities
dc.date.accessioned 2024-07-03T16:25:19Z
dc.date.available 2024-07-03T16:25:19Z
dc.date.issued 2023-04-20
dc.identifier.citation Geroin C, Artusi CA, Nonnekes J, Aquino C, Garg D, Dale ML, Schlosser D, Lai Y, Al-Wardat M, Salari M, Wolke R, Labou VT, Imbalzano G, Camozzi S, Merello M, Bloem BR, Capato T, Djaldetti R, Doherty K, Fasano A, Tibar H, Lopiano L, Margraf NG, Moreau C, Ugawa Y, Bhidayasiri R, Tinazzi M; International Parkinson and Movement Disorders Society Task Force on Postural Abnormalities. Axial Postural Abnormalities in Parkinsonism: Gaps in Predictors, Pathophysiology, and Management. Mov Disord. 2023 May;38(5):732-739. doi: 10.1002/mds.29377. Epub 2023 Apr 20 es_ES
dc.identifier.uri https://doi.org/10.1002/mds.29377
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/1136
dc.description.abstract Axial postural abnormalities are common and disabling motor complications of Parkinson's disease (PD) and parkinsonism. They consist of abnormal trunk or neck postures in the upright position, often interfering with daily life activities.1-5 A high number of patients with PD may develop one or more axial postural abnormalities, which may begin as minor forms, almost universal in persons with parkinsonism (eg, minor flexed posture of the trunk and lower limbs), and progress to severe forms such as camptocormia, antecollis, or Pisa syndrome in over 20% of patients,1 although the definitions of severe axial postural abnormalities were purely based on subjective/expert opinion. Drug-induced parkinsonism or progressive supranuclear palsy may also present axial postural abnormalities, and in multiple system atrophy these symptoms are more frequent than in PD and occur earlier in the disease course.2, 6 Because axial postural abnormalities are associated with an increased risk of falling, pain, and diminished quality of life, their proper prevention and management is warranted.2, 4, 5, 7, 8 However, to date, recommendations for multidisciplinary management and prevention remain an unmet need.3 Diagnosis is typically based on a simple clinical examination, whereas treatments (eg, pharmacological, physical therapy, and surgical treatments) have been evaluated only in small single-center studies that failed to show consistent, long-lasting improvement.2, 5, 8-10 The absence of reliable protocols for the assessment, treatment, and prevention of axial postural abnormalities in parkinsonism is probably due to the largely obscure pathophysiology and uncertainty about prognostic factors needed to estimate beneficial responses to therapy (eg, duration of axial postural abnormalities).2, 5, 8, 11-13 The aim of this viewpoint is to critically analyze the literature on axial postural abnormalities, identify the current issues and gaps, and formulate proposals for current clinical management and future research exploration. es_ES
dc.language.iso eng es_ES
dc.publisher Wiley es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.subject Muscular Atrophy, Spinal es_ES
dc.subject Atrofia Muscular Espinal es_ES
dc.subject Parkinson Disease es_ES
dc.subject Enfermedad de Parkinson es_ES
dc.subject Spinal Curvatures es_ES
dc.subject Curvaturas de la Columna Vertebral es_ES
dc.title Axial Postural Abnormalities in Parkinsonism: Gaps in Predictors, Pathophysiology, and Management es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Merello, Marcelo. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina.
dc.relation.ispartofVOLUME 38
dc.relation.ispartofNUMBER 5
dc.relation.ispartofPAGINATION 732-739
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Nueva York
dc.relation.ispartofTITLE Movement disorders
dc.relation.ispartofISSN 1531-8257
dc.type.snrd info:ar-repo/semantics/artículo es_ES


Dateien zu dieser Ressource

Das Dokument erscheint in:

Zur Kurzanzeige

DSpace Suche


Stöbern

Mein Benutzerkonto

Statistik