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Abstract TP217: Longitudinal Study of Young Patients With Embolic Stroke of Undetermined Source (ESUS)

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dc.contributor.author Lee, Sarah
dc.contributor.author MacLellan, Adam
dc.contributor.author Ameriso, Sebastián Francisco
dc.contributor.author Arauz-Gongora, Antonio
dc.contributor.author Häusler, Karl G.
dc.contributor.author Arnold, Marcel
dc.contributor.author Birnbaum, Lee A.
dc.contributor.author Martí-Fábregas, Joan
dc.contributor.author Olavarría, Verónica V.
dc.contributor.author Taylor, Amanda
dc.contributor.author Perera, Kanjana S.
dc.date.accessioned 2020-01-08T13:19:25Z
dc.date.available 2020-01-08T13:19:25Z
dc.date.issued 2019-01-30
dc.identifier.citation Lee S, MacLellan A, Ameriso SF, et al. Abstract TP217: Longitudinal Study of Young Patients With Embolic Stroke of Undetermined Source (ESUS). Stroke. 2019;50(Suppl_1):ATP217–ATP217. en_US
dc.identifier.uri https://doi.org/10.1161/str.50.suppl_1.TP217
dc.identifier.uri https://repositorio.fleni.org.ar/handle/123456789/157
dc.description.abstract Introduction: Stroke in young adults is not rare, and can have a devastating, lasting impact. Up to 20% of patients with Embolic Stroke of Undetermined Source (ESUS) are under 50 years of age; thus, determining potential causes and outcomes in this younger cohort may significantly impact clinical practice. We aim to describe clinical, laboratory and imaging characteristics of patients between 21 and 50 years of age with ESUS; determine rates of new-onset atrial fibrillation; and investigate predictors of recurrent stroke in this unique population. Methods: This is an ongoing multi-center, international registry, which plans to prospectively enroll 500 patients between the ages of 21-50 years with ESUS1 within 60 days. Clinical, laboratory and imaging data are documented at enrollment. Patients will be followed prospectively at 6, 12 and 18 months post-stroke via telephone interview to determine treatment and outcomes. End of enrollment is anticipated in mid-2019. Results: Majority of patients are male (63.7%), and males had a higher median age at stroke than females (43 versus 41 years, range 21-50). Figure 1 shows the geographical breakdown of recruited patients. Intravenous recombinant tissue plasminogen activator (tPA) was given to 26/146 (17.8%). Median modified Rankin Score at time of stroke was 1.0 (range 0-5.0). Table 1 contains baseline characteristics and diagnostic workup of 146/187 patients enrolled thus far. Conclusion: Demographics, stroke risk factors and recurrence rates may differ for younger patients with ESUS; thus, findings of this study could potentially shape clinical practice and ultimately improve outcomes for this at-risk population. en_US
dc.language.iso eng en_US
dc.publisher Lippincott Williams & Wilkins en_US
dc.relation.ispartofseries International Stroke Conference 2019 Poster Abstracts. Session Title: Community/Risk Factors Posters II
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Stroke en_US
dc.subject Accidente Cerebrovascular en_US
dc.subject Embolic Stroke of Undetermined Source en_US
dc.title Abstract TP217: Longitudinal Study of Young Patients With Embolic Stroke of Undetermined Source (ESUS) en_US
dc.type info:eu-repo/semantics/publishedVersion
dc.type info:eu-repo/semantics/other en_US
dc.description.fil Fil: Lee, Sarah. Stanford Health Care; Estados Unidos.
dc.description.fil Fil: MacLellan, Adam. Stanford Health Care; Estados Unidos.
dc.description.fil Fil: Ameriso, Sebastián Francisco. Fleni. Departamento de Neurología. Servicio de Neurología Vascular; Argentina.
dc.description.fil Fil: Arauz-Gongora, Antonio. Instituto Nacional de Neurologia y Neurocirugía "Manuel Velasco Suárez"; México.
dc.description.fil Fil: Häusler, Karl G. La Charité - Universitätsmedizin de Berlín. Center for Stroke Research; Alemania.
dc.description.fil Fil: Arnold, Marcel. Universitätsklinik für Neurologie. Inselspital; Suiza.
dc.description.fil Fil: Birnbaum, Lee A. University of Texas Health Science Center at San Antonio. Departments of Neurology and Neurosurgery; Estados Unidos.
dc.description.fil Fil: Martí-Fábregas, Joan. Hospital de la Santa Creu i Sant Pau. Neurology Services; España.
dc.description.fil Fil: Olavarría, Verónica V. Universidad del Desarrollo. Clínica Alemana de Santiago. Facultad de Medicina. Departamento de Medicina. Servicio de Neurología. Unidad de Tratamiento del Ataque Cerebrovascular; Chile.
dc.description.fil Fil: Taylor, Amanda. Geisinger Medical Center Pediatric Hematology & Oncology; Estados Unidos.
dc.description.fil Fil: Perera, Kanjana S. Population Health Research Institute and Hamilton Health Sciences. Stroke and Cognition Program; Estados Unidos.
dc.relation.ispartofVOLUME 50
dc.relation.ispartofNUMBER Suppl_1
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Baltimore
dc.relation.ispartofTITLE Stroke
dc.relation.ispartofISSN 1524-4628
dc.type.snrd info:ar-repo/semantics/artículo es_ES

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