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Association between neurological syndromes and Arbovirus in Buenos Aires - Relationship between Guillain Barre Syndrome, Encephalitis and Myelitis with Zika, Dengue and Chikungunya (P4.6-024)

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dc.contributor.author Kohler, Alejandro Alfredo
dc.contributor.author Farez, Mauricio Franco
dc.contributor.author Heck, Evelyn Sabrina
dc.contributor.author Barroso, Fabio Adrián
dc.contributor.author Bruno, Verónica
dc.date.accessioned 2020-01-09T13:46:20Z
dc.date.available 2020-01-09T13:46:20Z
dc.date.issued 2019-05-08
dc.identifier.citation Kohler A, Farez M, Heck E, Barroso FA, Bruno V. Association between neurological syndromes and Arbovirus in Buenos Aires - Relationship between Guillain Barre Syndrome, Encephalitis and Myelitis with Zika, Dengue and Chikungunya (P4.6-024). Neurology. 2019;92(15 Supplement):P4.6-024. en_US
dc.identifier.uri https://n.neurology.org/content/92/15_Supplement/P4.6-024
dc.identifier.uri https://repositorio.fleni.org.ar/handle/123456789/162
dc.description.abstract Objective: Analyze the association between Guillain Barre Syndrome (GBS), Infectious Encephalitis (IE) and Transverse Myelitis (TM) with secondary infections to arboviruses in hospitalized patients of Buenos Aires city. Background: Arbovirus infections are currently considered a pandemic in Argentina. There was a significant increase in the incidence of these infections during the 2014–2016 period, compared to previous years. Viruses such as Zika (ZIKV), Dengue (DENV) and Chikungunya (CHIKV) have been associated with different neurological syndromes, mainly with GBS and to a lesser extent with IE and TM. Design/Methods: We conducted a prospective cohort study, including all adult patients diagnosed with GBS, IE and TM, attended at our institution from 1/1/17 to 12/31/17. Samples of serum and / or cerebrospinal fluid were obtained. ELISA test was performed to detect antibodies against ZIKV, DENV and CHIKV. Clinical-epidemiological variables and complementary methods of both groups were recorded. We compared the GBS incidence results obtained in 2017 with respect to those presented in the last 10 years of our institution. Results: We included 39 patients with diagnosis of GBS (n=17), IE (n=18) and TM (n=4). 2 cases of GBS presented positive serology for ZIKV and 2 cases of IE presented positivity for DENV. During the period from 2015–2017, there was an increase in the incidence of GBS cases compared to previous years. Conclusions: In the present cohort, the incidence of cases of GBS, IE and MTA associated with arbovirus infections was relatively low. However, the cases associated with arbovirus infections showed differential clinical characteristics. We believe that epidemiological surveillance of neurological syndromes associated with arbovirus infections is essential to understand the magnitude of the problem at a national and regional level. en_US
dc.language.iso eng en_US
dc.publisher Lippincott Williams & Wilkins en_US
dc.rights info:eu-repo/semantics/openAccess
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Arboviruses en_US
dc.subject Arbovirus en_US
dc.subject Guillain-Barre Syndrome en_US
dc.subject Síndrome de Guillain-Barré en_US
dc.subject Encephalitis en_US
dc.subject Encefalitis en_US
dc.subject Myelitis en_US
dc.subject Mielitis en_US
dc.subject Zika Virus en_US
dc.subject Virus Zika en_US
dc.subject Dengue en_US
dc.subject Chikungunya virus en_US
dc.subject Virus Chikungunya en_US
dc.title Association between neurological syndromes and Arbovirus in Buenos Aires - Relationship between Guillain Barre Syndrome, Encephalitis and Myelitis with Zika, Dengue and Chikungunya (P4.6-024) en_US
dc.type info:eu-repo/semantics/publishedVersion
dc.type info:eu-repo/semantics/other en_US
dc.description.fil Fil: Kohler, Alejandro Alfredo. Fleni. Departamento de Neurología; Argentina.
dc.description.fil Fil: Farez, Mauricio Franco. Fleni. Centro para la Investigación de Enfermedades Neuroinmunológicas; Argentina.
dc.description.fil Fil: Heck, Evelyn Sabrina. Fleni. Centro para la Investigación de Enfermedades Neuroinmunológicas; Argentina.
dc.description.fil Fil: Barroso, Fabio Adrián. Fleni. Departamento de Neurología. Sección de Enfermedades Neuromusculares; Argentina.
dc.description.fil Fil: Bruno, Verónica. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina. University of Calgary. Department of Neurosciences; Canada.
dc.relation.ispartofVOLUME 92
dc.relation.ispartofNUMBER 15 Supplement
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Hagerstown
dc.relation.ispartofTITLE Neurology
dc.relation.ispartofISSN 1526-632X
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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