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Estudio epidemiológico de sepsis grave pediátrica en la República Argentina

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dc.contributor.author Jabornisky, Roberto
dc.contributor.author Sáenz, Silvia S.
dc.contributor.author Capocasa, Patricia
dc.contributor.author Jaen, Roxana
dc.contributor.author Moreno, Rodolfo P.
dc.contributor.author Landry, Luis
dc.contributor.author Rufach, Daniel
dc.contributor.author Santos, Silvia N.
dc.contributor.author Berrueta, Mabel
dc.contributor.author Carcillo, Joseph
dc.contributor.author Vassallo, Juan Carlos
dc.contributor.author Grupo de Investigación Clínica y Epidemiológica en Terapia Intensiva Pediátrica de la Sociedad Argentina de Pediatría
dc.contributor.other Castellano, Silvia
dc.contributor.other Kenny, Eugenia
dc.contributor.other Rodríguez, Edgardo
dc.date.accessioned 2020-12-01T12:31:22Z
dc.date.available 2020-12-01T12:31:22Z
dc.date.issued 2019-06
dc.identifier.citation Jaborniskya, Saenz, Capocasa, Jaen, Moreno, landry, Rufach, Santos, Berrueta, Carcillo, Vasallo, Grupo de Investigación Clínica y Epidemiológica en Terapia Intensiva Pediátrica. Estudio epidemiológico de sepsis grave pediátrica en la República Argentina. Arch Argent Pediatr. 2019 Jun;117(3):S135-S156. doi: 10.5546/aap.2019.eng.S135 en_US
dc.identifier.uri https://doi.org/10.5546/aap.2019.eng.S135
dc.identifier.uri https://repositorio.fleni.org.ar/handle/123456789/246
dc.description.abstract Introduction: Severe sepsis (SS) is one of the leading causes of pediatric mortality in Argentina. The objective was to describe the epidemiological characteristics and to analyze risk factors associated with mortality from SS among patients hospitalized in pediatric intensive care units (PICU) in Argentina. Population and methods: Observational, prospective cohort study among patients with SS hospitalized in PICUs in Argentina from 8/1/2008 to 9/30/2008. Results: Two thousand five hundred and fifty nine patients were admitted at 59 PICUs. A total of 315 patients (335 events) were included. Patients' median age was 8 months (1-182). The frequency was 13.8 %, and 28-day mortality was 31.6 %. Patients with a higher mortality were those who were coming from rural areas, had comorbidities at the time of admission or a history of cancer, had shock or acute respiratory distress syndrome (ARDS), were administered low-dose corticosteroids or vasoactive drugs or more than 60 ml/kg of fluid in the first hour and in the first 6hours, and had severe malnutrition. Following adjustment by severity using a multivariate logistic regression model, only coming from a rural area, having shock or ARDS remained associated with 28-day mortality. Forty per cent of patients received antibiotics 60 minutes after diagnosis. Conclusions: SS is an event with a high frequency and mortality in Argentina. In the severity adjusted multivariate analysis, only coming from a rural area, having ARDS and/or shock were associated with higher mortality. en_US
dc.language.iso eng en_US
dc.publisher Sociedad Argentina de Pediatría en_US
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Argentina en_US
dc.subject Hospital Mortality en_US
dc.subject Mortalidad Hospitalaria en_US
dc.subject Intensive Care Units, Pediatric en_US
dc.subject Unidades de Cuidado Intensivo Pediátrico en_US
dc.subject Sepsis en_US
dc.subject Fluid Therapy en_US
dc.subject Fluidoterapia en_US
dc.title Estudio epidemiológico de sepsis grave pediátrica en la República Argentina en_US
dc.type info:eu-repo/semantics/publishedVersion
dc.type info:eu-repo/semantics/article en_US
dc.description.fil Fil: Jabornisky, Roberto. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Sáenz, Silvia S. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Capocasa, Patricia. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Jaen, Roxana. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Moreno, Rodolfo P. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Landry, Luis. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Rufach, Daniel. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Santos, Silvia N. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Berrueta, Mabel. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Carcillo, Joseph. Children's Hospital of Pittsburgh; Estados Unidos.
dc.description.fil Fil: Vassallo, Juan Carlos. Sociedad Argentina de Pediatría. Comité Nacional de Emergencias y Cuidados Críticos; Argentina.
dc.description.fil Fil: Castellano, Silvia. Fleni; Argentina.
dc.description.fil Fil: Kenny, Eugenia. Fleni; Argentina.
dc.description.fil Fil: Rodríguez, Edgardo. Fleni; Argentina.
dc.relation.ispartofVOLUME 117
dc.relation.ispartofNUMBER 3
dc.relation.ispartofPAGINATION S135-S156
dc.relation.ispartofCOUNTRY Argentina
dc.relation.ispartofCITY Buenos Aires
dc.relation.ispartofTITLE Archivos argentinos de pediatría
dc.relation.ispartofISSN 1668-3501
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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