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Fall in the Proportion of Atherothrombotic Strokes During the Last Decade

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dc.contributor.author Rosales, Julieta Soledad
dc.contributor.author Alet, Matías Javier
dc.contributor.author Pujol Lereis, Virginia Andrea
dc.contributor.author Ameriso, Sebastián Francisco
dc.date.accessioned 2021-05-04T12:37:19Z
dc.date.available 2021-05-04T12:37:19Z
dc.date.issued 2020-12
dc.identifier.citation Rosales, J.S., Alet, M.J., Lereis, V.A.P., Ameriso, S.F., 2020. Fall in the Proportion of Atherothrombotic Strokes During the Last Decade. J Stroke Cerebrovasc Dis 29, 105257. https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105257 es_ES
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/455
dc.identifier.uri https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105257
dc.description.abstract Objective: To determine the proportion of subtypes of ischemic strokes, vascular risk factors and treatment prior to stroke between 1997 and 2018 in a single institution in Argentina. Methods: Demographics, risk factors, medications and TOAST subtypes were assessed and compared in ischemic stroke patients admitted during two periods of time, 1997-2007 (P1) and 2008-2018 (P2). Results: There were 2747 patients (64% men, aged 67 ±15 years), 920 subjects in P1 and 1827 in P2. Age and gender distribution did not change over time. Proportion of large artery atherothrombotic strokes decreased from 29% in P1 to 14% in P2 (p <0.0001) and small vessel strokes from 15% to 11% (p <0.05). Cardioembolic and undetermined strokes increased from 17 to 25% (p <0.0001) and from 30% to 41% (p <0.0001), respectively. There were no changes in stroke of other etiologies (9% in both periods). Detection of atrial fibrillation increased from 14% to 19% (p<0.001). Use of medications prior to stroke increased for aspirin from 27% to 45% (p <0.0001), for antihypertensive drugs from 26% to 62% (p <0.0001), for statins from 14% to 42% (p<0.0001) and for anticoagulants from 4% to 9% (p<0.0001). Conclusions: The proportion of strokes associated to large and small vessel atherosclerosis is declining in our population with an increase in the proportion of cardioembolic and undetermined strokes. Better management of risk factors and higher prevalence and/or better screening for atrial fibrillation could explain, at least in part, these findings. es_ES
dc.language.iso eng es_ES
dc.publisher Saunders es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Risk Factors es_ES
dc.subject Factores de Riesgo es_ES
dc.subject Stroke es_ES
dc.subject Accidente Cerebrovascular es_ES
dc.subject Ischemic Stroke es_ES
dc.title Fall in the Proportion of Atherothrombotic Strokes During the Last Decade es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Rosales, Julieta Soledad. Fleni. Departamento de Neurología. Servicio de Neurología Vascular; Argentina.
dc.description.fil Fil: Alet, Matías Javier. Fleni. Departamento de Neurología. Servicio de Neurología Vascular; Argentina.
dc.description.fil Fil: Pujol Lereis, Virginia Andrea. Fleni. Departamento de Neurología. Servicio de Neurología Vascular; Argentina.
dc.description.fil Fil: Ameriso, Sebastián Francisco. Fleni. Departamento de Neurología. Servicio de Neurología Vascular; Argentina.
dc.relation.ispartofVOLUME 29
dc.relation.ispartofNUMBER 12
dc.relation.ispartofPAGINATION 105257
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Filadelfia
dc.relation.ispartofTITLE Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.
dc.relation.ispartofISSN 1532-8511
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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