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Nosology and Phenomenology of Psychosis in Movement Disorders

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dc.contributor.author Rossi, Malco Damián
dc.contributor.author Farcy, Nicole
dc.contributor.author Starkstein, Sergio E.
dc.contributor.author Merello, Marcelo
dc.date.accessioned 2021-05-05T14:43:06Z
dc.date.available 2021-05-05T14:43:06Z
dc.date.issued 2020-01-07
dc.identifier.citation Rossi, M.D., Farcy, N., Starkstein, S.E., Merello, M., 2020a. Nosology and Phenomenology of Psychosis in Movement Disorders. Mov Disord Clin Pract 7, 140–153. https://doi.org/10.1002/mdc3.12882 es_ES
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/459
dc.identifier.uri https://doi.org/10.1002/mdc3.12882
dc.description.abstract Background: Psychotic symptoms, such as delusions and hallucinations, are part of the clinical picture of several conditions presenting movement disorders. Phenomenology and epidemiology of psychosis in Parkinson's disease have received wide attention; however, the presence of psychosis in other movement disorders is, comparatively, less well known. Objectives: To review psychotic symptoms present in different movement disorders. Methods: A comprehensive and structured literature search was performed to identify and analyze data on patients with movement disorders and comorbid psychosis. Results: In monogenic parkinsonisms, such as PARK-GBA, PARK-LRRK2, and PARK-SNCA, visual hallucinations related to dopamine replacement therapy are frequent as well as are delusions in PARK-LRRK2 and PARK-SNCA, but not in PARK-GBA. Different types of delusions and hallucinations are found in Huntington's disease and other choreic disorders. In Tourette's syndrome, paranoid delusions as well as visual, olfactory, and auditory hallucinations have been described, which usually develop after an average of 10 years of disease. Delusions in ataxias are more frequent in ATX-TBP, ATX-ATN1, and ATX-ATXN3, whereas it is rare in Friedreich's ataxia. Psychosis is also a prominent and frequent clinical feature in Fahr's disease, Wilson's disease, neurodegeneration with brain iron accumulation, and some lysosomal storage disorders, whereas it is uncommon in atypical parkinsonisms and dystonia. Psychosis usually occurs at late disease stages, but may appear as onset symptoms of the disease, especially in Wilson's disease, Huntington's disease, late-onset Tays-Sachs, and Niemann-Pick. Conclusion: Psychosis is a frequent comorbidity in most hyper- and hypokinetic movement disorders. Appropriate recognition is relevant both in the early and late disease stages. es_ES
dc.language.iso eng es_ES
dc.publisher Wiley es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Delusions es_ES
dc.subject Deluciones es_ES
dc.subject Hallucinations es_ES
dc.subject Alucinaciones es_ES
dc.subject Psychotic Disorders es_ES
dc.subject Trastornos Psicóticos es_ES
dc.title Nosology and Phenomenology of Psychosis in Movement Disorders es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Rossi, Malco Damián. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina.
dc.description.fil Fil: Merello, Marcelo. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina. Universidad Católica Argentina; Argentina.
dc.description.fil Fil: Farcy, Nicole. Fleni. Departamento de Neurología. Servicio de Movimientos Anormales; Argentina.
dc.description.fil Fil: Starkstein, Sergio E. University of Western Australia. School of Psychiatry and Clinical Neurosciences; Australia.
dc.relation.ispartofVOLUME 7
dc.relation.ispartofNUMBER 2
dc.relation.ispartofPAGINATION 140-153.
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Nueva York
dc.relation.ispartofTITLE Movement disorders clinical practice
dc.relation.ispartofISSN 2330-1619
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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