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Trigeminal Neuralgia Crisis - Intravenous Phenytoin as Acute Rescue Treatment

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dc.contributor.author Schnell, Susana
dc.contributor.author Marrodán, Mariano
dc.contributor.author Acosta, Julián Nicolás
dc.contributor.author Bonamico, Lucas
dc.contributor.author Goicochea, María Teresa
dc.date.accessioned 2021-05-07T16:24:18Z
dc.date.available 2021-05-07T16:24:18Z
dc.date.issued 2020-11
dc.identifier.citation Schnell, S., Marrodan, M., Acosta, J.N., Bonamico, L., Goicochea, M.T., 2020. Trigeminal Neuralgia Crisis - Intravenous Phenytoin as Acute Rescue Treatment. Headache. https://doi.org/10.1111/head.13963 es_ES
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/467
dc.identifier.uri https://doi.org/10.1111/head.13963
dc.description.abstract Objective: The aim of this retrospective cohort study was to analyze responses to intravenous (IV) phenytoin (PHT) for trigeminal neuralgia (TN) crisis in a group of patients treated at our institution. Background: TN is one of the most common causes of facial pain. Its treatment relies on preventive therapy with either carbamazepine or oxcarbazepine. During severe pain episodes, patients may be unable to eat, drink, or even swallow oral medication, requiring in-hospital treatment. There is scarce evidence to support IV medication use for TN, making management of this condition difficult. Methods: We reviewed clinical records of patients with TN crisis consulting the emergency department at a tertiary neurological referral center in Buenos Aires, Argentina, treated with IV PHT as analgesic strategy, and with at least 1-month posttreatment follow-up. Demographic features, magnetic resonance imaging findings, and therapeutic management were analyzed. Results: Thirty-nine patients with TN were included, 18 (46.2%) receiving IV PHT more than once (total number of infusions administered, 65). Immediate pain relief was observed in 89.2% (58/65) and 15.4% (10/65) presented side effects. Conclusions: We recommend IV PHT as acute rescue treatment in TN crisis. es_ES
dc.language.iso eng es_ES
dc.publisher Wiley es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Facial Neuralgia es_ES
dc.subject Neuralgia Facial es_ES
dc.title Trigeminal Neuralgia Crisis - Intravenous Phenytoin as Acute Rescue Treatment es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Schnell, Susana. Fleni. Departamento de Neurología; Argentina.
dc.description.fil Fil: Marrodán, Mariano. Fleni. Departamento de Neurología. Servicio de Neuroinmunología y Enfermedades Desmielinizantes; Argentina.
dc.description.fil Fil: Goicochea, María Teresa. Fleni. Departamento de Neurología. Clínica del Dolor. Clínica de Cefaleas; Argentina.
dc.description.fil Fil: Bonamico, Lucas. Fleni. Departamento de Neurología. Clínica del Dolor. Clínica de Cefaleas; Argentina.
dc.description.fil Fil: Acosta, Julián Nicolás. Fleni. Departamento de Neurología; Argentina.
dc.relation.ispartofVOLUME 60
dc.relation.ispartofNUMBER 10
dc.relation.ispartofPAGINATION 2247-2253.
dc.relation.ispartofCOUNTRY Estados Unidos
dc.relation.ispartofCITY Nueva York
dc.relation.ispartofTITLE Headache
dc.relation.ispartofISSN 1526-4610
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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