Browsing Neurociencias by Subject "Nanog Homeobox Protein"

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Kat6b Modulates Oct4 and Nanog Binding to Chromatin in Embryonic Stem Cells and Is Required for Efficient Neural Differentiation

Cosentino, María Soledad; Oses, Camila; Vázquez Echegaray, Camila; Solari, Claudia; Waisman, Ariel; Álvarez, Yanina; Petrone, María Victoria; Francia, Marcos; Schultz, Marcelo; Sevlever, Gustavo Emilio; Miriuka, Santiago Gabriel; Levi, Valeria; Guberman, Alejandra S. (Academic Press, 2019-03-15)

Chromatin remodeling is fundamental for the dynamical changes in transcriptional programs that occur during development and stem cell differentiation. The histone acetyltransferase Kat6b is relevant for neurogenesis in ...
The pluripotency transcription factor Nanog represses glutathione reductase gene expression in mouse embryonic stem cells

Solari, Claudia; Petrone, María Victoria; Toro, Ayelén; Vázquez Echegaray, Camila; Cosentino, María Soledad; Waisman, Ariel; Francia, Marcos; Barañao, Lino; Miriuka, Santiago Gabriel; Guberman, Alejandra S. (Biomed Central, 2019-07-01)

OBJECTIVE: Redox homeostasis maintenance is essential to bring about cellular functions. Particularly, embryonic stem cells (ESCs) have high fidelity mechanisms for DNA repair, high activity of different antioxidant enzymes ...

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