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Browsing Neurociencias by Title

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  • 188 MicroRNA characterization in equine induced pluripotent stem cells 
    Moro, Lucía Natalia; Amín, Guadalupe; Furmento, Verónica Alejandra; Waisman, Ariel; Neiman, Gabriel; La Greca, Alejandro; Santín Velazque, Natalia Lucía; Luzzani, Carlos Daniel; Sevlever, Gustavo Emilio; Vichera, Gabriel; Miriuka, Santiago Gabriel (Csiro Publishing, 2018-12-03)
    Cell reprogramming has been well described in mouse and human cells. The expression of specific microRNAs has demonstrated to be essential for pluripotent maintenance and cell differentiation, but not much information is ...
  • A critical pathway in human development: C19MC micrornas regulates FGF2 response in a model of human pluripotent stem cells cardiac differentiation 
    Möbbs, Alan Miqueas; Garate, Ximena; Scarafía, María Agustina; Colli, Carolina; Moro, Lucía Natalia; Luzzani, Carlos Daniel; Waisman, Ariel; La Greca, Alejandro; Miriuka, Santiago Gabriel (Fundación Revista Medicina, 2021-11)
  • A miR-137-Related Biological Pathway of Risk for Schizophrenia Is Associated With Human Brain Emotion Processing 
    Pergola, Giulio; Rampino, Antonio; Sportelli, Leonardo; Borcuk, Christopher James; Passiatore, Roberta; Di Carlo, Pasquale; Marakhovskaia, Aleksandra; Fazio, Leonardo; Amoroso, Nicola; Castro, Mariana Nair; Domenici, Enrico; Gennarelli, Massimo; Khlghatyan, Jivan; Christos Kikidis, Gianluca; Lella, Annalisa; Magri, Chiara; Monaco, Alfonso; Papalino, Marco; Parihar, Madhur; Popolizio, Teresa (Elsevier, 2023-11-22)
    Background: miR-137 is a microRNA involved in brain development, regulating neurogenesis and neuronal maturation. Genome-wide association studies have implicated miR-137 in schizophrenia risk but do not explain its involvement ...
  • A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects 
    Acosta-Uribe, Juliana; Aguillón, David; Cochran, J. Nicholas; Giraldo, Margarita; Madrigal, Lucía; Killingsworth, Bradley W.; Singhal, Rijul; Labib, Sarah; Alzate, Diana; Velilla, Lina M.; Moreno, Sonia; García, Gloria P.; Saldarriaga, Amanda; Piedrahita, Francisco; Hincapié, Liliana; López, Hugo E.; Perumal, Nithesh; Surace, Ezequiel Ignacio; Itzcovich, Tatiana; Allegri, Ricardo Francisco (BioMed Central, 2022-03-08)
    Background: The Colombian population, as well as those in other Latin American regions, arose from a recent tri-continental admixture among Native Americans, Spanish invaders, and enslaved Africans, all of whom passed ...
  • Abnormal brain network community structure related to psychological stress in schizophrenia 
    Castro, Mariana Nair; Bocaccio, Hernán; De Pino, Gabriela; Sánchez, Stella Maris; Wainsztein, Agustina Edith; Drucaroff, Lucas Javier; Costanzo, Elsa; Crossley, Nicolas; Mirta Fabiana, Villarreal; Guinjoan, Salvador Martín (Elsevier, 2023-02-15)
    Recent functional imaging studies in schizophrenia consistently report a disruption of brain connectivity. However, most of these studies analyze the brain connectivity during resting state. Since psychological stress is ...
  • Acute severe hypoxia induces apoptosis of human pluripotent stem cells by a HIF-1α and P53 independent mechanism 
    Mucci, Sofía; Isaja, Luciana; Rodríguez Varela, María Soledad; Ferriol Laffouillere, Sofía Luján; Marazita, Mariela Claudia; Videla Richardson, Guillermo Agustín; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Nature Publishing Group, 2022-10-05)
    Human embryonic and induced pluripotent stem cells are self-renewing pluripotent stem cells (hPSCs) that can differentiate into a wide range of specialized cells. Although moderate hypoxia (5% O2) improves hPSC self-renewal, ...
  • Analysis of the expression of PIWI-interacting RNAs during cardiac differentiation of human pluripotent stem cells 
    La Greca, Alejandro; Scarafía, María Agustina; Hernández Cañás, María Clara; Pérez, Nelba; Castañeda, Sheila; Colli, Carolina; Miqueas Möbbs, Alan; Santín Velazque, Natalia Lucía; Neiman, Gabriel; Garate, Ximena; Aban, Cyntia; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel (bioRxiv, 2019-05-21)
    El artículo es un preprint que aún no ha pasado por revisión por pares PIWI-interacting RNAs (piRNAs) are a class of non-coding RNAs initially thought to be restricted almost exclusively to germ line cells. In recent ...
  • Author Correction: AHR is a Zika virus host factor and a candidate target for antiviral therapy 
    Giovannoni, Federico; Bosch, Irene; Manganeli Polonio, Carolina; Torti, María F.; Wheeler, Michael A.; Li, Zhaorong; Romorini, Leonardo; Rodríguez Varela, María Soledad; Rothhammer, Veit; Barroso, Andreia; Tjon, Emily C.; Sanmarco, Liliana M.; Takenaka, Maisa C.; Sadegh Modaresi, Seyed Mohamad; Gutiérrez-Vázquez, Cristina; Ghabdan Zanluqui, Nágela; Barreto Dos Santos, Nilton; Demarchi Munhoz, Carolina; Wang, Zhongyan; Damonte, Elsa B.; Sherr, David; Gehrke, Lee; Schatzmann Peron, Jean Pierre; Garcia, Cybele C.; Quintana, Francisco J. (Nature Publishing Group, 2020-10)
  • Author Correction: Retrieval of retrained and reconsolidated memories are associated with a distinct neural network 
    Bavassi, Luz; Forcato, Cecilia; Fernández, Rodrigo Sebastián; De Pino, Gabriela; Pedreira, María Eugenia; Villarreal, Mirta Fabiana (Nature Publishing Group, 2019-04-10)
    A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. Erratum for Retrieval of retrained and reconsolidated memories are ...
  • Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle 
    Waisman, Ariel; Norris, Alessandra; Costa, Martín Elías; Kopinke, Daniel (Nature Publishing Group, 2021-01-22)
    Skeletal muscle has the remarkable ability to regenerate. However, with age and disease muscle strength and function decline. Myofiber size, which is affected by injury and disease, is a critical measurement to assess ...
  • The avalanche-like behaviour of large-scale haemodynamic activity from wakefulness to deep sleep 
    Bocaccio, Hernán; Pallavicini, Carla; Castro, Mariana Nair; Sánchez, Stella Maris; De Pino, Gabriela; Laufs, Helmut; Villarreal, Mirta Fabiana; Tagliazucchi, Enzo (Royal Society, 2019-09-11)
    Increasing evidence suggests that responsiveness is associated with critical or near-critical cortical dynamics, which exhibit scale-free cascades of spatio-temporal activity. These cascades, or 'avalanches', have been ...
  • Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification 
    Schottlaender, Lucía V.; Abeti, Rosella; Jaunmuktane, Zane; Macmillan, Carol; Chelban, Viorica; O'Callaghan, Benjamin; McKinley, John; Maroofian, Reza; Efthymiou, Stephanie; Athanasiou Fragkouli, Alkyoni; Forbes, Raeburn; Soutar, Marc P.M.; Livingston, John H.; Kalmar, Bernardett; Swayne, Orlando; Hotton, Gary; SYNAPS Study Group; Pittman, Alan; Launchbury, Francesca; Mendes de Oliveira, João Ricardo; de Grandis, Maria; Richard Loendt, Angela; Althonayan, Juri; McDonnell, Gavin; Carr, Aisling; Khan, Suliman; Beetz, Christian; Bisgin, Atil; Bozdogan, Sevcan Tug; Begtrup, Amber; Torti, Erin; Greensmith, Linda; Giunti, Paola; Morrison, Patrick J.; Brandner, Sebastian; Aurrand-Lions, Michel; Houlden, Henry (Cell Press, 2020-02-05)
    Primary familial brain calcification (PFBC) is a rare neurodegenerative disorder characterized by a combination of neurological, psychiatric, and cognitive decline associated with calcium deposition on brain imaging. To ...
  • Body mass index, waist circumference, insulin, and leptin plasma levels differentiate between clozapine-responsive and clozapine-resistant schizophrenia 
    Hönig, Guillermo; Daray, Federico M.; Rodante, Demián; Drucaroff, Lucas Javier; Gutiérrez, María Laura; Lenze, Mariela; García Bournissen, Facundo; Wikinski, Silvia (Sage, 2023-06-28)
    Background: Between 25% and 50% of patients suffering from treatment-resistant schizophrenia fail to achieve a clinical response with clozapine. The rapid identification and treatment of this subgroup of patients represents ...
  • Broad-Spectrum Antiviral Effect of Cannabidiol Against Enveloped and Nonenveloped Viruses 
    Marquez, Agostina B.; Vicente, Josefina; Castro, Eliana; Vota, Daiana; Rodríguez Varela, María Soledad; Lanza Castronuovo, Priscila A.; Fuentes, Giselle M.; Parise, Alejandro R.; Romorini, Leonardo; Alvarez, Diego E.; Bueno, Carlos A.; Ramirez, Cristina L.; Alaimo, Agustina; García, Cybele C. (Mary Ann Liebert, 2023-09-08)
    Introduction: Cannabidiol (CBD), the main non-psychoactive cannabinoid of the Cannabis sativa plant, is a powerful antioxidant compound that in recent years has increased interest due to causes effects in a wide range of ...
  • CDK5 Deficiency Does not Impair Neuronal Differentiation of Human Induced Pluripotent Stem Cells but Affects Neurite Outgrowth 
    Mucci, Sofía; Clas, Giulia Solange; Allio, Camila Paola; Rodríguez Varela, María Soledad; Isaja, Luciana; Marazita, Mariela; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Humana Press, 2024-06-28)
    Cyclin-dependent kinase 5 (CDK5) is a protein kinase involved in neuronal homeostasis and development critical for neuronal survival. Besides, its deregulation is linked to neurodegenerative pathologies such as Alzheimer's ...
  • Cell cycle dynamics of mouse embryonic stem cells in the ground state and during transition to formative pluripotency 
    Waisman, Ariel; Sevlever, Federico; Costa, Martín Elías; Cosentino, María Soledad; Miriuka, Santiago Gabriel; Ventura, Alejandra C.; Guberman, Alejandra S. (Nature Publishing Group, 2019-05-29)
    Mouse embryonic stem cells (mESCs) can be maintained as homogeneous populations in the ground state of pluripotency. Release from this state in minimal conditions allows to obtain cells that resemble those of the early ...
  • celldeath: A tool for detection of cell death in transmitted light microscopy images by deep learning-based visual recognition 
    La Greca, Alejandro; Pérez, Nelba; Castañeda, Sheila; Milone, Paula Melania; Scarafía, María Agustina; Möbbs, Alan Miqueas; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel (Public Library of Science, 2021-06-24)
    Cell death experiments are routinely done in many labs around the world, these experiments are the backbone of many assays for drug development. Cell death detection is usually performed in many ways, and requires time and ...
  • Chemical hypoxia induces apoptosis of human pluripotent stem cells by a NOXA-mediated HIF-1α and HIF-2α independent mechanism 
    Isaja, Luciana; Mucci, Sofía; Vera, Jonathan; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Morris-Hanon, Olivia; Videla Richardson, Guillermo Agustín; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Nature Publishing Group, 2020-10-26)
    Human embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are self-renewing human pluripotent stem cells (hPSCs) that can differentiate to a wide range of specialized cells. Notably, hPSCs enhance their ...
  • Chromatographic Scalable Method to Isolate Engineered Extracellular Vesicles Derived from Mesenchymal Stem Cells for the Treatment of Liver Fibrosis in Mice 
    Domínguez, Luciana M.; Bueloni, Bárbara; Cantero, María José; Albornoz, Milagros; Pacienza, Natalia; Biani, María Celeste; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel; García, Mariana; Atorrasagasti Fernández, María Catalina; Yannarelli, Gustavo; Bayo, Juan; Fiore, Esteban; Mazzolini, Guillermo (MDPI, 2023-05-31)
    New therapeutic options for liver cirrhosis are needed. Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have emerged as a promising tool for delivering therapeutic factors in regenerative medicine. Our aim ...
  • Consecuencias Neurológicas y Psiquiátricas a largo plazo (6 meses) en pacientes con COVID leve de la comunidad 
    Allegri, Ricardo Francisco; Calandri, Ismael Luis; Caride, Alejandro; Román, Fabián; Llera, J.; Palma, A.; Bartoloni, L.; Carozzela, A.; González Sanz, P.; Mouchet, E.; Fernández Díaz, Paula C.; Morasso, C.; Tarulla, Adriana (Universidad de la Costa, 2022-06-08)
    Las complicaciones neurológicas a largo plazo de la infección por coronavirus han sido descriptas en los pacientes hospitalizados en el episodio agudo. De ellos el 63% presentaron fatiga y debilidad muscular, el 26% ...

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