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Listar Neurociencias por título

Listar Neurociencias por título

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  • Optic tract and internal capsule lesion in a patient with Wernicke-Korsakoff syndrome 
    Hernández, Micaela Anahí; Varela, Francisco José; Bensi, Catalina (Universidad de la Costa, 2020-12-07)
    A 72-year-old man, presented with a one-week history of confusion and an anterograde amnesic disorder accompanied by confabulation, with lack of insight to his symptoms. Medical history included alcohol abuse and admitted ...
  • Palbociclib Effectively Halts Proliferation but Fails to Induce Senescence in Patient-Derived Glioma Stem Cells 
    Morris-Hanon, Olivia; Marazita, Mariela Claudia; Romorini, Leonardo; Isaja, Luciana; Fernandez-Espinosa, Damián Darío; Sevlever, Gustavo Emilio; Scassa, María Élida; Videla Richardson, Guillermo Agustín (Springer, 2019-05-23)
    Glioblastoma multiforme is the most aggressive primary brain tumor. Current knowledge suggests that the growth and recurrence of these tumors are due in part to the therapy-resistant glioma stem cell subpopulation, which ...
  • Peritumoral adipose tissue promotes lipolysis and white adipocytes browning by paracrine action 
    Pagnotta, Priscila; Gantov, Mariana; Fletcher, Sabrina; Lombardi, Antonella; Crosbie, María Lujan; Santiso, Natalia; Ursino, Anabela; Frascarolli, Celeste; Amato, Alicia; Dreszman, Rubén; Calvo, Juan Carlos; Toneatto, Judith (Frontiers Research Foundation, 2023-04-26)
    Background: Stromal adipocytes and tumor breast epithelial cells undergo a mutual metabolic adaptation within tumor microenvironment. Therefore, browning and lipolysis occur in cancer associated adipocytes (CAA). However, ...
  • Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness 
    Sanz Perl, Yonatan; Pallavicini, Carla; Pérez Ipiña, Ignacio; Demertzi, Athena; Bonhomme, Vincent; Martial, Charlotte; Panda, Rajanikant; Annen, Jitka; Ibañez, Agustín; Kringelbach, Morten; Deco, Gustavo; Laufs, Helmut; Sitt, Jacobo D.; Laureys, Steven; Tagliazucchi, Enzo (Public Library of Science, 2021-07-27)
    Consciousness transiently fades away during deep sleep, more stably under anesthesia, and sometimes permanently due to brain injury. The development of an index to quantify the level of consciousness across these different ...
  • PIWI-interacting RNAs are differentially expressed during cardiac differentiation of human pluripotent stem cells 
    La Greca, Alejandro; Scarafía, María Agustina; Hernández Cañás, María Clara; Pérez, Nelba; Castañeda, Sheila; Colli, Carolina; Miqueas Möbbs, Alan; Santín Velazque, Natalia Lucía; Neiman, Gabriel; Garate, Ximena; Aban, Cyntia; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel (Public Library of Science, 2020-05-05)
    PIWI-interacting RNAs (piRNAs) are a class of non-coding RNAs initially thought to be restricted exclusively to germline cells. In recent years, accumulating evidence has demonstrated that piRNAs are actually expressed in ...
  • PluriBAC: A Versatile Baculovirus-Based Modular System to Express Heterologous Genes in Different Biotechnological Platforms 
    Amorós Morales, Leslie C.; Marchesini, Abril; Gómez Bergna, Santiago M.; García Fallit, Matías; Tongiani, Silvana E.; Vásquez, Larisa; Ferrelli, María Leticia; Videla Richardson, Guillermo Agustín; Candolfi, Marianela; Romanowski, Víctor; Pidre, Matías L. (MDPI, 2023-09-23)
    Baculoviruses are insect-specific pathogens widely used in biotechnology. In particular, the Autographa californica nucleopolyhedrovirus (AcMNPV) has been exploited as a platform for bio-inputs production. This is why the ...
  • The pluripotency transcription factor Nanog represses glutathione reductase gene expression in mouse embryonic stem cells 
    Solari, Claudia; Petrone, María Victoria; Toro, Ayelén; Vázquez Echegaray, Camila; Cosentino, María Soledad; Waisman, Ariel; Francia, Marcos; Barañao, Lino; Miriuka, Santiago Gabriel; Guberman, Alejandra S. (Biomed Central, 2019-07-01)
    OBJECTIVE: Redox homeostasis maintenance is essential to bring about cellular functions. Particularly, embryonic stem cells (ESCs) have high fidelity mechanisms for DNA repair, high activity of different antioxidant enzymes ...
  • Protocol for morphometric analysis of neurons derived from human pluripotent stem cells 
    Mucci, Sofía; Rodríguez Varela, María Soledad; Isaja, Luciana; Ferriol-Laffouillere, Sofía Luján; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Cell Press, 2022-06-18)
    The analysis of morphological features of neurons derived from human pluripotent stem cells (hPSCs) is important to describe neuronal phenotypes and changes observed throughout development. Using free and easily accessible ...
  • R534C mutation in hERG causes a trafficking defect in iPSC-derived cardiomyocytes from patients with type 2 long QT syndrome 
    Mesquita, Fernanda C.P.; Arantes, Paulo C.; Kasai-Brunswick, Tais Hanae; Araujo, Dayana S.; Gubert, Fernanda; Monnerat, Gustavo; Silva dos Santos, Danúbia; Neiman, Gabriel; Leitão, Isabela C.; Barbosa, Raiana A. Q.; Coutinho, Jorge L.; Vaz, Isadora M.; dos Santos, Marcus N.; Borgonovo, Tamara; Cruz, Fernando E. S.; Miriuka, Santiago Gabriel; Medei, Emiliano H.; Campos de Carvalho, Antonio C.; Carvalho, Adriana B. (Nature Publishing Group, 2019-12-16)
    Patient-specific cardiomyocytes obtained from induced pluripotent stem cells (CM-iPSC) offer unprecedented mechanistic insights in the study of inherited cardiac diseases. The objective of this work was to study a type 2 ...
  • Retrieval of Retrained and Reconsolidated Memories Are Associated With a Distinct Neural Network 
    Bavassi, Luz; Forcato, Cecilia; Fernández, Rodrigo Sebastián; De Pino, Gabriela; Pedreira, María Eugenia; Villarreal, Mirta Fabiana (Nature Publishing Group, 2019-01-28)
    Consolidated memories can persist from a single day to years, and persistence is improved by retraining or retrieval-mediated plasticity. One retrieval-based way to strengthen memory is the reconsolidation process. ...
  • Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer 
    Marks, María Paula; Giménez, Carla Alejandra; Isaja, Luciana; Vera, Mariana Belén; Borzone, Francisco Raúl; Pereyra-Bonnet, Federico; Romorini, Leonardo; Videla Richardson, Guillermo Agustín; Chasseing, Norma Alejandra; Calvo, Juan Carlos; Vellón, Luciano (Springer-Verlag, 2024-02-28)
    Purpose: De novo synthesis of cholesterol and its rate-limiting enzyme, 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMGCR), is deregulated in tumors and critical for tumor cell survival and proliferation. However, ...
  • Silencing of the transcription factors Oct4, Sox2, Klf4, c-Myc or Nanoghas different effect on teratoma growth 
    Schlee Villodre, Emilly; Bettega Felipe, Karina; Zanotta Oyama, Mayumi; Hehn de Oliveira, Francine; da Costa Lopez, Patrícia Luciana; Solari, Claudia; Sevlever, Gustavo Emilio; Guberman, Alejandra S.; Lenz, Guido (Elsevier, 2019-07-25)
    Induced pluripotent stem cells (iPSC) have a great potential, but their clinical application depends on finding strategies to abolish their tumorigenic potential. The use of Oct4, Sox2, Klf4, c-Myc and Nanog to generate ...
  • Simple Microcontact Printing Technique to Obtain Cell Patterns by Lithography Using Grayscale, Photopolymer Flexographic Mold, and PDMS 
    Gimenez, Rocio; Pérez-Sosa, Camilo; Bourguignon, Natalia; Miriuka, Santiago Gabriel; Bhansali, Shekhar; Arroyo, Carlos R.; Debut, Alexis; Lerner, Betiana; Pérez, Maximiliano S. (MDPI AG, 2022-10-08)
    Microcontact printing using PDMS embossing tools and its variations have aroused the interest of a wide spectrum of research fields, hence the feasibility of defining micro and nanoscale patterns. In this work, we have ...
  • Single cell transfection of human-induced pluripotent stem cells using a droplet-based microfluidic system 
    Pérez-Sosa, Camilo; Sanluis-Verdes, Anahí; Waisman, Ariel; Lombardi, Antonella; Rosero, Gustavo; La Greca, Alejandro; Bhansali, Shekhar; Bourguignon, Natalia; Luzzani, Carlos Daniel; Pérez, Maximiliano S.; Miriuka, Santiago Gabriel; Lerner, Betiana (Royal Society Publishing, 2022-01-12)
    Microfluidic tools have recently made possible many advances in biological and biomedical research. Research in fields such as physics, engineering, chemistry and biology have combined to produce innovation in microfluidics ...
  • SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy 
    Muñiz, Javier Andrés; Facal, Carolina Lucía; Urrutia, Leandro; Clerici-Delville, Ramiro; Damianich, Ana; Ferrario, Juan Esteban; Falasco, Germán; Avale, María Elena (Frontiers Media S.A., 2022-09-05)
    Tau is a microtubule-associated protein predominantly expressed in neurons, which participates in microtubule polymerization and axonal transport. Abnormal tau metabolism leads to neurodegenerative diseases named tauopathies, ...
  • Spectral signatures of serotonergic psychedelics and glutamatergic dissociatives 
    Pallavicini, Carla; Vilas, Martina G.; Villarreal, Mirta Fabiana; Zamberlan, Federico; Muthukumaraswamy, Suresh; Nutt, David; Carhart-Harris, Robin; Tagliazucchi, Enzo (Elsevier, 2019-06-24)
    Classic serotonergic psychedelics are remarkable for their capacity to induce reversible alterations in consciousness of the self and the surroundings, mediated by agonism at serotonin 5-HT2A receptors. The subjective ...
  • Spirituality and Cognitive Neurosciences 
    Allegri, Ricardo Francisco; Román, Fabián; Barceló Martínez, Ernesto (Universidad de la Costa, 2023-10-23)
  • SUMO conjugation susceptibility of Akt/protein kinase B affects the expression of the pluripotency transcription factor Nanog in embryonic stem cells 
    Francia, Marcos; Stortz, Martin; Vazquez Echegaray, Camila; Oses, Camila; Verneri, Paula; Petrone, María Victoria; Toro, Ayelén; Waisman, Ariel; Miriuka, Santiago Gabriel; Cosentino, María Soledad; Levi, Valeria; Guberman, Alejandra S. (Public Library of Science, 2021-07-09)
    Akt/PKB is a kinase involved in the regulation of a wide variety of cell processes. Its activity is modulated by diverse post-translational modifications (PTMs). Particularly, conjugation of the small ubiquitin-related ...
  • Tau mis-splicing correlates with motor impairments and striatal dysfunction in a model of tauopathy 
    Damianich, Ana; Facal, Carolina Lucía; Muñiz, Javier Andrés; Mininni, Camilo; Soiza-Reilly, Mariano; Ponce de León, Magdalena; Urrutia, Leandro; Falasco, Germán; Ferrario, Juan Esteban; Avale, María Elena (Oxford, 2021-06-01)
    Tauopathies are neurodegenerative diseases caused by the abnormal metabolism of the microtubule associated protein Tau, which is highly expressed in neurons and critically involved in microtubule dynamics. In the adult ...
  • The entropic tongue: Disorganization of natural language under LSD 
    Sanz, Camila; Pallavicini, Carla; Carrillo, Facundo; Zamberlan, Federico; Sigman, Mariano; Mota, Natalia; Copelli, Mauro; Ribeiro, Sidarta; Nutt, David; Carhart-Harris, Robin; Tagliazucchi, Enzo (Academic Press, 2020-12-08)
    Serotonergic psychedelics have been suggested to mirror certain aspects of psychosis, and, more generally, elicit a state of consciousness underpinned by increased entropy of on-going neural activity. We investigated the ...

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