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Listar Neurociencias por título

Listar Neurociencias por título

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  • R534C mutation in hERG causes a trafficking defect in iPSC-derived cardiomyocytes from patients with type 2 long QT syndrome 
    Mesquita, Fernanda C.P.; Arantes, Paulo C.; Kasai-Brunswick, Tais Hanae; Araujo, Dayana S.; Gubert, Fernanda; Monnerat, Gustavo; Silva dos Santos, Danúbia; Neiman, Gabriel; Leitão, Isabela C.; Barbosa, Raiana A. Q.; Coutinho, Jorge L.; Vaz, Isadora M.; dos Santos, Marcus N.; Borgonovo, Tamara; Cruz, Fernando E. S.; Miriuka, Santiago Gabriel; Medei, Emiliano H.; Campos de Carvalho, Antonio C.; Carvalho, Adriana B. (Nature Publishing Group, 2019-12-16)
    Patient-specific cardiomyocytes obtained from induced pluripotent stem cells (CM-iPSC) offer unprecedented mechanistic insights in the study of inherited cardiac diseases. The objective of this work was to study a type 2 ...
  • Retrieval of Retrained and Reconsolidated Memories Are Associated With a Distinct Neural Network 
    Bavassi, Luz; Forcato, Cecilia; Fernández, Rodrigo Sebastián; De Pino, Gabriela; Pedreira, María Eugenia; Villarreal, Mirta Fabiana (Nature Publishing Group, 2019-01-28)
    Consolidated memories can persist from a single day to years, and persistence is improved by retraining or retrieval-mediated plasticity. One retrieval-based way to strengthen memory is the reconsolidation process. ...
  • Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer 
    Marks, María Paula; Giménez, Carla Alejandra; Isaja, Luciana; Vera, Mariana Belén; Borzone, Francisco Raúl; Pereyra-Bonnet, Federico; Romorini, Leonardo; Videla Richardson, Guillermo Agustín; Chasseing, Norma Alejandra; Calvo, Juan Carlos; Vellón, Luciano (Springer-Verlag, 2024-02-28)
    Purpose: De novo synthesis of cholesterol and its rate-limiting enzyme, 3-hydroxy-3-methylglutharyl-coenzyme A reductase (HMGCR), is deregulated in tumors and critical for tumor cell survival and proliferation. However, ...
  • Silencing of the transcription factors Oct4, Sox2, Klf4, c-Myc or Nanoghas different effect on teratoma growth 
    Schlee Villodre, Emilly; Bettega Felipe, Karina; Zanotta Oyama, Mayumi; Hehn de Oliveira, Francine; da Costa Lopez, Patrícia Luciana; Solari, Claudia; Sevlever, Gustavo Emilio; Guberman, Alejandra S.; Lenz, Guido (Elsevier, 2019-07-25)
    Induced pluripotent stem cells (iPSC) have a great potential, but their clinical application depends on finding strategies to abolish their tumorigenic potential. The use of Oct4, Sox2, Klf4, c-Myc and Nanog to generate ...
  • Simple Microcontact Printing Technique to Obtain Cell Patterns by Lithography Using Grayscale, Photopolymer Flexographic Mold, and PDMS 
    Gimenez, Rocio; Pérez-Sosa, Camilo; Bourguignon, Natalia; Miriuka, Santiago Gabriel; Bhansali, Shekhar; Arroyo, Carlos R.; Debut, Alexis; Lerner, Betiana; Pérez, Maximiliano S. (MDPI AG, 2022-10-08)
    Microcontact printing using PDMS embossing tools and its variations have aroused the interest of a wide spectrum of research fields, hence the feasibility of defining micro and nanoscale patterns. In this work, we have ...
  • Single cell transfection of human-induced pluripotent stem cells using a droplet-based microfluidic system 
    Pérez-Sosa, Camilo; Sanluis-Verdes, Anahí; Waisman, Ariel; Lombardi, Antonella; Rosero, Gustavo; La Greca, Alejandro; Bhansali, Shekhar; Bourguignon, Natalia; Luzzani, Carlos Daniel; Pérez, Maximiliano S.; Miriuka, Santiago Gabriel; Lerner, Betiana (Royal Society Publishing, 2022-01-12)
    Microfluidic tools have recently made possible many advances in biological and biomedical research. Research in fields such as physics, engineering, chemistry and biology have combined to produce innovation in microfluidics ...
  • SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy 
    Muñiz, Javier Andrés; Facal, Carolina Lucía; Urrutia, Leandro; Clerici-Delville, Ramiro; Damianich, Ana; Ferrario, Juan Esteban; Falasco, Germán; Avale, María Elena (Frontiers Media S.A., 2022-09-05)
    Tau is a microtubule-associated protein predominantly expressed in neurons, which participates in microtubule polymerization and axonal transport. Abnormal tau metabolism leads to neurodegenerative diseases named tauopathies, ...
  • Spectral signatures of serotonergic psychedelics and glutamatergic dissociatives 
    Pallavicini, Carla; Vilas, Martina G.; Villarreal, Mirta Fabiana; Zamberlan, Federico; Muthukumaraswamy, Suresh; Nutt, David; Carhart-Harris, Robin; Tagliazucchi, Enzo (Elsevier, 2019-06-24)
    Classic serotonergic psychedelics are remarkable for their capacity to induce reversible alterations in consciousness of the self and the surroundings, mediated by agonism at serotonin 5-HT2A receptors. The subjective ...
  • Spirituality and Cognitive Neurosciences 
    Allegri, Ricardo Francisco; Román, Fabián; Barceló Martínez, Ernesto (Universidad de la Costa, 2023-10-23)
  • SUMO conjugation susceptibility of Akt/protein kinase B affects the expression of the pluripotency transcription factor Nanog in embryonic stem cells 
    Francia, Marcos; Stortz, Martin; Vazquez Echegaray, Camila; Oses, Camila; Verneri, Paula; Petrone, María Victoria; Toro, Ayelén; Waisman, Ariel; Miriuka, Santiago Gabriel; Cosentino, María Soledad; Levi, Valeria; Guberman, Alejandra S. (Public Library of Science, 2021-07-09)
    Akt/PKB is a kinase involved in the regulation of a wide variety of cell processes. Its activity is modulated by diverse post-translational modifications (PTMs). Particularly, conjugation of the small ubiquitin-related ...
  • Tau mis-splicing correlates with motor impairments and striatal dysfunction in a model of tauopathy 
    Damianich, Ana; Facal, Carolina Lucía; Muñiz, Javier Andrés; Mininni, Camilo; Soiza-Reilly, Mariano; Ponce de León, Magdalena; Urrutia, Leandro; Falasco, Germán; Ferrario, Juan Esteban; Avale, María Elena (Oxford, 2021-06-01)
    Tauopathies are neurodegenerative diseases caused by the abnormal metabolism of the microtubule associated protein Tau, which is highly expressed in neurons and critically involved in microtubule dynamics. In the adult ...
  • The entropic tongue: Disorganization of natural language under LSD 
    Sanz, Camila; Pallavicini, Carla; Carrillo, Facundo; Zamberlan, Federico; Sigman, Mariano; Mota, Natalia; Copelli, Mauro; Ribeiro, Sidarta; Nutt, David; Carhart-Harris, Robin; Tagliazucchi, Enzo (Academic Press, 2020-12-08)
    Serotonergic psychedelics have been suggested to mirror certain aspects of psychosis, and, more generally, elicit a state of consciousness underpinned by increased entropy of on-going neural activity. We investigated the ...
  • The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma 
    García, Marcela N.; Palma, María Belén; Verine, Jerome; Miriuka, Santiago Gabriel; Inda, Ana María; Errecalde, Ana Lía; Desgrandchamps, François; Carosella, Edgardo D.; Tronik-Le Roux, Diana (BioMed Central, 2020-07-03)
    Background: Clear cell renal cell carcinoma (ccRCC), the most aggressive renal cancer, is characterized by early lymph node metastases and bad prognosis. Most therapies targeting advanced or metastatic ccRCC are based, as ...
  • The role of microfluidics and 3D-bioprinting in the future of exosome therapy 
    Amondarain, Mikele; Gallego, Idoia; Puras, Gustavo; Saenz-Del-Burgo, Laura; Luzzani, Carlos Daniel; Pedraz, José Luis (Elsevier, 2023-06-09)
    Exosome-based strategies constitute a promising tool for therapeutics, avoiding potential immunogenic and tumorigenic side-effects of cell therapies. However, the collection of a suitable exosome pool, and the need for ...
  • Towards the Journal of Applied Cognitive Neuroscience 
    Allegri, Ricardo Francisco; Roman, Fabián; Barceló Martínez, Ernesto (Universidad de la Costa, 2020-12-07)
    In his book The Structure of Science Evolution, Thomas Khum defines a paradigmas “a set of beliefs, values and accepted techniques that define the exercise of a scientific discipline”. A new paradigm is a change of vision, ...
  • Unifying turbulent dynamics framework distinguishes different brain states 
    Escrichs, Anira; Sanz Perl, Yonatan; Uribe, Carme; Camara, Estela; Türker, Basak; Pyatigorskaya, Nadya; López-González, Ane; Pallavicini, Carla; Panda, Rajanikant; Annen, Jitka; Gosseries, Olivia; Laureys, Steven; Naccache, Lionel; Sitt, Jacobo D.; Laufs, Helmut; Tagliazucchi, Enzo; Kringelbach, Morten; Deco, Gustavo (Nature Publishing Group UK, 2022-05-29)
    Significant advances have been made by identifying the levels of synchrony of the underlying dynamics of a given brain state. This research has demonstrated that non-conscious dynamics tend to be more synchronous than in ...
  • Wound Healing by Allogeneic Transplantation of Specific Subpopulation From Human Umbilical Cord Mesenchymal Stem Cells 
    Palma, María Belén; Luzzani, Carlos Daniel; Andrini, Laura B.; Riccillo, Fernando; Buero, Guillermo; Pelinski, Pablo; Inda, Ana María; Errecalde, Ana Lía; Miriuka, Santiago Gabriel; Carosella, Edgardo D.; Garcia, Marcela N. (Sage, 2021-05-11)
    In normal physiological conditions, restoration of a functional epidermal barrier is highly efficient; nevertheless, when it fails, one of the main consequences is a chronic ulcerative skin defect, one of the most frequently ...

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