Neurociencias: Envíos recientes

  • A critical pathway in human development: C19MC micrornas regulates FGF2 response in a model of human pluripotent stem cells cardiac differentiation 
    Möbbs, Alan Miqueas; Garate, Ximena; Scarafia, María Agustina; Colli, Carolina; Moro, Lucía Natalia; Luzzani, Carlos Daniel; Waisman, Ariel; La Greca, Alejandro; Miriuka, Santiago Gabriel (Fundación Revista Medicina, 2021-11)
    Human pluripotent stem cells (hPSC) have the capacity to self-renew and differentiate in vitro into all cell types of the organism, and it is an established model for early human embryo development. Recently, we found ...
  • Simple Microcontact Printing Technique to Obtain Cell Patterns by Lithography Using Grayscale, Photopolymer Flexographic Mold, and PDMS 
    Gimenez, Rocio; Pérez-Sosa, Camilo; Bourguignon, Natalia; Miriuka, Santiago Gabriel; Bhansali, Shekhar; Arroyo, Carlos R.; Debut, Alexis; Lerner, Betiana; Pérez, Maximiliano S. (MDPI AG, 2022-10-08)
    Microcontact printing using PDMS embossing tools and its variations have aroused the interest of a wide spectrum of research fields, hence the feasibility of defining micro and nanoscale patterns. In this work, we have ...
  • A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects 
    Acosta-Uribe, Juliana; Aguillón, David; Cochran, J. Nicholas; Giraldo, Margarita; Madrigal, Lucía; Killingsworth, Bradley W.; Singhal, Rijul; Labib, Sarah; Alzate, Diana; Velilla, Lina M.; Moreno, Sonia; García, Gloria P.; Saldarriaga, Amanda; Piedrahita, Francisco; Hincapié, Liliana; López, Hugo E.; Perumal, Nithesh; Surace, Ezequiel Ignacio; Itzcovich, Tatiana; Allegri, Ricardo Francisco (BioMed Central, 2022-03-08)
    Background: The Colombian population, as well as those in other Latin American regions, arose from a recent tri-continental admixture among Native Americans, Spanish invaders, and enslaved Africans, all of whom passed ...
  • Neurosciences and Neuro post-COVID-19 
    Allegri, Ricardo Francisco; Román, Fabián; Barceló Martínez, Ernesto (Universidad de la Costa, 2021-03-23)
    Editorial
  • Consecuencias Neurológicas y Psiquiátricas a largo plazo (6 meses) en pacientes con COVID leve de la comunidad 
    Allegri, Ricardo Francisco; Calandri, Ismael Luis; Caride, A.; Román, Fabián; Llera, J.; Palma, A.; Bartoloni, L.; Carozzela, A.; González Sanz, P.; Mouchet, E.; Fernández Díaz, Paula C.; Morasso, C.; Tarulla, Adriana (Universidad de la Costa, 2022-06-08)
    Las complicaciones neurológicas a largo plazo de la infección por coronavirus han sido descriptas en los pacientes hospitalizados en el episodio agudo. De ellos el 63% presentaron fatiga y debilidad muscular, el 26% ...
  • Acute severe hypoxia induces apoptosis of human pluripotent stem cells by a HIF-1α and P53 independent mechanism 
    Mucci, Sofía; Isaja, Luciana; Rodríguez Varela, María Soledad; Ferriol Laffouillere, Sofía Luján; Marazita, Mariela Claudia; Videla Richardson, Guillermo Agustín; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Nature Publishing Group, 2022-10-05)
    Human embryonic and induced pluripotent stem cells are self-renewing pluripotent stem cells (hPSCs) that can differentiate into a wide range of specialized cells. Although moderate hypoxia (5% O2) improves hPSC self-renewal, ...
  • SMaRT modulation of tau isoforms rescues cognitive and motor impairments in a preclinical model of tauopathy 
    Muñiz, Javier Andrés; Facal, Carolina Lucía; Urrutia, Leandro; Clerici-Delville, Ramiro; Damianich, Ana; Ferrario, Juan Esteban; Falasco, Germán; Avale, María Elena (Frontiers Media S.A., 2022-09-05)
    Tau is a microtubule-associated protein predominantly expressed in neurons, which participates in microtubule polymerization and axonal transport. Abnormal tau metabolism leads to neurodegenerative diseases named tauopathies, ...
  • Single cell transfection of human-induced pluripotent stem cells using a droplet-based microfluidic system 
    Pérez-Sosa, Camilo; Sanluis-Verdes, Anahí; Waisman, Ariel; Lombardi, Antonella; Rosero, Gustavo; La Greca, Alejandro; Bhansali, Shekhar; Bourguignon, Natalia; Luzzani, Carlos Daniel; Pérez, Maximiliano S.; Miriuka, Santiago Gabriel; Lerner, Betiana (Royal Society Publishing, 2022-01-12)
    Microfluidic tools have recently made possible many advances in biological and biomedical research. Research in fields such as physics, engineering, chemistry and biology have combined to produce innovation in microfluidics ...
  • Natural language signatures of psilocybin microdosing 
    Sanz, Camila; Cavanna, Federico; Muller, Stephanie; de la Fuente, Laura A.; Zamberlan, Federico; Palmucci, Matías; Janeckova, Lucie; Kuchar, Martin; Carrillo, Facundo; García, Adolfo M.; Pallavicini, Carla; Tagliazucchi, Enzo (Springer-Verlag, 2022-09)
    Rationale: Serotonergic psychedelics are being studied as novel treatments for mental health disorders and as facilitators of improved well-being, mental function, and creativity. Recent studies have found mixed results ...
  • GEMA—An Automatic Segmentation Method for Real-Time Analysis of Mammalian Cell Growth in Microfluidic Devices 
    Isa-Jara, Ramiro; Pérez-Sosa, Camilo; Macote-Yparraguirre, Erick; Revollo, Natalia; Lerner, Betiana; Miriuka, Santiago Gabriel; Delrieux, Claudio; Pérez, Maximiliano S.; Mertelsmann, Roland (MDPI, 2022-10-14)
    Nowadays, image analysis has a relevant role in most scientific and research areas. This process is used to extract and understand information from images to obtain a model, knowledge, and rules in the decision process. ...
  • Galectins as Emerging Glyco-Checkpoints and Therapeutic Targets in Glioblastoma 
    Videla Richardson, Guillermo Agustín; Morris Hanon, Olivia; Torres, Nicolás I.; Esquivel, Myrian Inés; Vera, Mariana Belén; Ripari, Luisina Belén; Croci, Diego O.; Sevlever, Gustavo Emilio; Rabinovich, Gabriel A. (Molecular Diversity Preservation International, 2021-12-28)
    Despite recent advances in diagnosis and treatment, glioblastoma (GBM) represents the most common and aggressive brain tumor in the adult population, urging identification of new rational therapeutic targets. Galectins, a ...
  • Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study 
    Cavanna, Federico; Muller, Stephanie; de la Fuente, Laura A.; Zamberlan, Federico; Palmucci, Matías; Janeckova, Lucie; Kuchar, Martin; Pallavicini, Carla (Nature Pub. Group, 2022-08-02)
    The use of low sub-perceptual doses of psychedelics ("microdosing") has gained popularity in recent years. Although anecdotal reports claim multiple benefits associated with this practice, the lack of placebo-controlled ...
  • Protocol for morphometric analysis of neurons derived from human pluripotent stem cells 
    Mucci, Sofía; Rodríguez Varela, María Soledad; Isaja, Luciana; Ferriol-Laffouillere, Sofía Luján; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Cell Press, 2022-06-18)
    The analysis of morphological features of neurons derived from human pluripotent stem cells (hPSCs) is important to describe neuronal phenotypes and changes observed throughout development. Using free and easily accessible ...
  • Unifying turbulent dynamics framework distinguishes different brain states 
    Escrichs, Anira; Sanz Perl, Yonatan; Uribe, Carme; Camara, Estela; Türker, Basak; Pyatigorskaya, Nadya; López-González, Ane; Pallavicini, Carla; Panda, Rajanikant; Annen, Jitka; Gosseries, Olivia; Laureys, Steven; Naccache, Lionel; Sitt, Jacobo D.; Laufs, Helmut; Tagliazucchi, Enzo; Kringelbach, Morten; Deco, Gustavo (Nature Publishing Group UK, 2022-05-29)
    Significant advances have been made by identifying the levels of synchrony of the underlying dynamics of a given brain state. This research has demonstrated that non-conscious dynamics tend to be more synchronous than in ...
  • Embryoid Bodies-Based Multilineage Differentiation of Human Embryonic Stem Cells Grown on Feeder-Free Conditions 
    Isaja, Luciana; Ferriol Laffouillere, Sofía Luján; Mucci, Sofía; Rodríguez Varela, María Soledad; Romorini, Leonardo (Springer, 2021-10-06)
    Human embryonic stem cells (hESCs) can differentiate into any cell lineage (pluripotency potential) derived from the three germ layers: ectoderm, mesoderm, and endoderm. Pluripotency is usually demonstrated in vitro by ...
  • Effect of Embryo Aggregation on In Vitro Development of Adipose-Derived Mesenchymal Stem Cell-Derived Bovine Clones 
    Savy, Virginia; Alberio, Virgilia; Vans Landschoot, Geraldina; Moro, Lucía Natalia; Olea, Fernanda Daniela; Rodríguez-Álvarez, Lleretny; Salamone, Daniel Felipe (Mary Ann Liebert, 2021-10-12)
    Somatic cell nuclear transfer (SCNT) is a method with unique ability to reprogram the epigenome of a fully differentiated cell. However, its efficiency remains extremely low. In this work, we assessed and combined two ...
  • The entropic tongue: Disorganization of natural language under LSD 
    Sanz, Camila; Pallavicini, Carla; Carrillo, Facundo; Zamberlan, Federico; Sigman, Mariano; Mota, Natalia; Copelli, Mauro; Ribeiro, Sidarta; Nutt, David; Carhart-Harris, Robin; Tagliazucchi, Enzo (Academic Press, 2020-12-08)
    Serotonergic psychedelics have been suggested to mirror certain aspects of psychosis, and, more generally, elicit a state of consciousness underpinned by increased entropy of on-going neural activity. We investigated the ...
  • Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness 
    Sanz Perl, Yonatan; Pallavicini, Carla; Pérez Ipiña, Ignacio; Demertzi, Athena; Bonhomme, Vincent; Martial, Charlotte; Panda, Rajanikant; Annen, Jitka; Ibañez, Agustín; Kringelbach, Morten; Deco, Gustavo; Laufs, Helmut; Sitt, Jacobo D.; Laureys, Steven; Tagliazucchi, Enzo (Public Library of Science, 2021-07-27)
    Consciousness transiently fades away during deep sleep, more stably under anesthesia, and sometimes permanently due to brain injury. The development of an index to quantify the level of consciousness across these different ...
  • SUMO conjugation susceptibility of Akt/protein kinase B affects the expression of the pluripotency transcription factor Nanog in embryonic stem cells 
    Francia, Marcos; Stortz, Martin; Vazquez Echegaray, Camila; Oses, Camila; Verneri, Paula; Petrone, María Victoria; Toro, Ayelén; Waisman, Ariel; Miriuka, Santiago Gabriel; Cosentino, María Soledad; Levi, Valeria; Guberman, Alejandra S. (Public Library of Science, 2021-07-09)
    Akt/PKB is a kinase involved in the regulation of a wide variety of cell processes. Its activity is modulated by diverse post-translational modifications (PTMs). Particularly, conjugation of the small ubiquitin-related ...
  • Hand bone conduction sound study by using the DSP Logger MX 300 
    Adler, Melanie Victoria; Fialá Sánchez, Mariana; Martini, Constanza; Vartabedian, Luciana Mariam; Zazzali, Matías Nicolás; Quintero Rincón, Antonio (Sociedad Argentina de Bioingeniería, 2020)
    Bone conduction is the transmission of acoustic energy to the inner ear by different paths involving the bones of the skull. In this work, we use the path the hand provides in order to transmit the sound coming from the ...

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