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Auflistung Neurociencias.artículos nach Autor "Guberman, Alejandra S."

Auflistung Neurociencias.artículos nach Autor "Guberman, Alejandra S."

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  • Cell cycle dynamics of mouse embryonic stem cells in the ground state and during transition to formative pluripotency 
    Waisman, Ariel; Sevlever, Federico; Costa, Martín Elías; Cosentino, María Soledad; Miriuka, Santiago Gabriel; Ventura, Alejandra C.; Guberman, Alejandra S. (Nature Publishing Group, 2019-05-29)
    Mouse embryonic stem cells (mESCs) can be maintained as homogeneous populations in the ground state of pluripotency. Release from this state in minimal conditions allows to obtain cells that resemble those of the early ...
  • Deep Learning Neural Networks Highly Predict Very Early Onset of Pluripotent Stem Cell Differentiation 
    Waisman, Ariel; La Greca, Alejandro; Möbbs, Alan Miqueas; Scarafía, María Agustina; Santín Velazque, Natalia Lucía; Neiman, Gabriel; Moro, Lucía Natalia; Luzzani, Carlos Daniel; Sevlever, Gustavo Emilio; Guberman, Alejandra S.; Miriuka, Santiago Gabriel (Elsevier, 2019-04-09)
    Deep learning is a significant step forward for developing autonomous tasks. One of its branches, computer vision, allows image recognition with high accuracy thanks to the use of convolutional neural networks (CNNs). Our ...
  • Integrin alpha-5 subunit is critical for the early stages of human pluripotent stem cell cardiac differentiation 
    Neiman, Gabriel; Scarafía, María Agustina; La Greca, Alejandro; Santín Velazque, Natalia Lucía; Garate, Ximena; Waisman, Ariel; Möbbs, Alan Miqueas; Kasai-Brunswick, Tais Hanae; Mesquita, Fernanda C.P.; Martire-Greco, Daiana; Moro, Lucía Natalia; Luzzani, Carlos Daniel; Bastos Carvalho, Adriana; Sevlever, Gustavo Emilio; Campos de Carvalho, Antonio C.; Guberman, Alejandra S.; Miriuka, Santiago Gabriel (Nature Publishing Group, 2019-12-02)
    The stem cell niche has a strong influence in the differentiation potential of human pluripotent stem cells with integrins playing a major role in communicating cells with the extracellular environment. However, it is not ...
  • Kat6b Modulates Oct4 and Nanog Binding to Chromatin in Embryonic Stem Cells and Is Required for Efficient Neural Differentiation 
    Cosentino, María Soledad; Oses, Camila; Vázquez Echegaray, Camila; Solari, Claudia; Waisman, Ariel; Álvarez, Yanina; Petrone, María Victoria; Francia, Marcos; Schultz, Marcelo; Sevlever, Gustavo Emilio; Miriuka, Santiago Gabriel; Levi, Valeria; Guberman, Alejandra S. (Academic Press, 2019-03-15)
    Chromatin remodeling is fundamental for the dynamical changes in transcriptional programs that occur during development and stem cell differentiation. The histone acetyltransferase Kat6b is relevant for neurogenesis in ...
  • The pluripotency transcription factor Nanog represses glutathione reductase gene expression in mouse embryonic stem cells 
    Solari, Claudia; Petrone, María Victoria; Toro, Ayelén; Vázquez Echegaray, Camila; Cosentino, María Soledad; Waisman, Ariel; Francia, Marcos; Barañao, Lino; Miriuka, Santiago Gabriel; Guberman, Alejandra S. (Biomed Central, 2019-07-01)
    OBJECTIVE: Redox homeostasis maintenance is essential to bring about cellular functions. Particularly, embryonic stem cells (ESCs) have high fidelity mechanisms for DNA repair, high activity of different antioxidant enzymes ...
  • Silencing of the transcription factors Oct4, Sox2, Klf4, c-Myc or Nanoghas different effect on teratoma growth 
    Schlee Villodre, Emilly; Bettega Felipe, Karina; Zanotta Oyama, Mayumi; Hehn de Oliveira, Francine; da Costa Lopez, Patrícia Luciana; Solari, Claudia; Sevlever, Gustavo Emilio; Guberman, Alejandra S.; Lenz, Guido (Elsevier, 2019-07-25)
    Induced pluripotent stem cells (iPSC) have a great potential, but their clinical application depends on finding strategies to abolish their tumorigenic potential. The use of Oct4, Sox2, Klf4, c-Myc and Nanog to generate ...
  • SUMO conjugation susceptibility of Akt/protein kinase B affects the expression of the pluripotency transcription factor Nanog in embryonic stem cells 
    Francia, Marcos; Stortz, Martin; Vazquez Echegaray, Camila; Oses, Camila; Verneri, Paula; Petrone, María Victoria; Toro, Ayelén; Waisman, Ariel; Miriuka, Santiago Gabriel; Cosentino, María Soledad; Levi, Valeria; Guberman, Alejandra S. (Public Library of Science, 2021-07-09)
    Akt/PKB is a kinase involved in the regulation of a wide variety of cell processes. Its activity is modulated by diverse post-translational modifications (PTMs). Particularly, conjugation of the small ubiquitin-related ...

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