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Browsing Neurociencias.artículos by Title

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  • Romorini, Leonardo; Baweja, Sukriti; Martin Mateos, Rosa Maria; Mehta, Gautam; Jalan-Sakrikar, Nidhi (Frontiers Media, 2023-04-19)
    Resumen no disponible
  • Savy, Virginia; Alberio, Virgilia; Vans Landschoot, Geraldina; Moro, Lucía Natalia; Olea, Fernanda Daniela; Rodríguez-Álvarez, Lleretny; Salamone, Daniel Felipe (Mary Ann Liebert, 2021-10-12)
    Somatic cell nuclear transfer (SCNT) is a method with unique ability to reprogram the epigenome of a fully differentiated cell. However, its efficiency remains extremely low. In this work, we assessed and combined two ...
  • Martire-Greco, Daiana; La Greca, Alejandro; Castillo Montañez, Luis; Biani, María Celeste; Lombardi, Antonella; Birnberg-Weiss, Federico; Norris, Alessandra; Sacerdoti, Flavia; Amaral, María Marta; Rodrigues-Rodriguez, Nahuel; Pittaluga, Jose Ramón; Furmento, Verónica Alejandra; Landoni, Verónica Inés; Miriuka, Santiago Gabriel; Luzzani, Carlos Daniel; Fernández, Gabriela Cristina (Lippincott Williams & Wilkins, 2023-04-11)
    Background : Mesenchymal stem cells (MSCs) can be activated by different bacterial toxins. Lipopolysaccharides and Shiga Toxin (Stx) are the main toxins necessary for hemolytic uremic syndrome development. The main etiological ...
  • Isaja, Luciana; Ferriol Laffouillere, Sofía Luján; Mucci, Sofía; Rodríguez Varela, María Soledad; Romorini, Leonardo (Springer, 2021-10-06)
    Human embryonic stem cells (hESCs) can differentiate into any cell lineage (pluripotency potential) derived from the three germ layers: ectoderm, mesoderm, and endoderm. Pluripotency is usually demonstrated in vitro by ...
  • García Fallit, Matías; Pidre, Matías L.; Asad, Antonela S.; Peña Agudelo, Jorge A.; Vera, Mariana Belén; Nicola Candia, Alejandro J.; Sagripanti, Sofia B.; Pérez Küper, Melanie; Amorós Morales, Leslie C.; Marchesini, Abril; Gonzalez, Nazareno; Caruso, Carla M.; Romanowski, Víctor; Seilicovich, Adriana; Videla Richardson, Guillermo Agustín; Zanetti, Flavia A.; Candolfi, Marianela (MDPI, 2023-02-22)
    We aimed to assess the potential of baculoviral vectors (BV) for brain cancer gene therapy. We compared them with adenoviral vectors (AdV), which are used in neuro-oncology, but for which there is pre-existing immunity. ...
  • Genoud, Valeria; Stortz, Martin; Waisman, Ariel; Berardino, Bruno G.; Verneri, Paula; Dansey, Virginia; Salvatori, Melina; Remes Lenicov, Federico; Levi, Valeria (PLoS One, 2021-02-26)
    Real-time reverse transcription PCR (RT-qPCR) is the gold-standard technique for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection in nasopharyngeal swabs specimens. The analysis by RT-qPCR usually ...
  • Videla Richardson, Guillermo Agustín; Morris Hanon, Olivia; Torres, Nicolás I.; Esquivel, Myrian Inés; Vera, Mariana Belén; Ripari, Luisina Belén; Croci, Diego O.; Sevlever, Gustavo Emilio; Rabinovich, Gabriel A. (Molecular Diversity Preservation International, 2021-12-28)
    Despite recent advances in diagnosis and treatment, glioblastoma (GBM) represents the most common and aggressive brain tumor in the adult population, urging identification of new rational therapeutic targets. Galectins, a ...
  • Isa-Jara, Ramiro; Pérez-Sosa, Camilo; Macote-Yparraguirre, Erick; Revollo, Natalia; Lerner, Betiana; Miriuka, Santiago Gabriel; Delrieux, Claudio; Pérez, Maximiliano S.; Mertelsmann, Roland (MDPI, 2022-10-14)
    Nowadays, image analysis has a relevant role in most scientific and research areas. This process is used to extract and understand information from images to obtain a model, knowledge, and rules in the decision process. ...
  • Nievas, Micaela; Romorini, Leonardo; Isaja, Luciana; Clas, Giulia S.; Rodríguez Varela, María Soledad; Mucci, Sofía; Itzcovich, Tatiana; de Ambrosi, Bruno; Scassa, María Élida; Sevlever, Gustavo Emilio; Surace, Ezequiel Ignacio; Marazita, Mariela Claudia (Elsevier, 2023-03-22)
    Human induced pluripotent stem cell (hiPSC) line INEUi001-A was reprogrammed from peripheral blood mononuclear cells (PBMC) using the lentiviral-hSTEMCCA-loxP vector. PBMCs were obtained from a 75- year-old female ALS/FTD ...
  • Isaja, Luciana; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Mucci, Sofía; Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Niikado, Matías; Ferriol Laffouillere, Sofía Luján; Allegri, Ricardo Francisco; Martinetto, Horacio; Sevlever, Gustavo Emilio; Scassa, María Élida; Surace, Ezequiel Ignacio; Romorini, Leonardo (Elsevier, 2021-04-05)
    Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained from a skin biopsy of a 72-year-old Caucasian male ...
  • Moro, Lucía Natalia; Viale, Diego Luis; Bastón, Juan Ignacio; Arnold, Victoria; Suva, Mariana; Wiedenmann, Elisabet; Olguín, Martín; Miriuka, Santiago Gabriel; Vichera, Gabriel (Nature Publishing Group, 2020-08-24)
    The application of new technologies for gene editing in horses may allow the generation of improved sportive individuals. Here, we aimed to knock out the myostatin gene (MSTN), a negative regulator of muscle mass development, ...
  • Amín, Guadalupe; Castañeda, Sheila; Zabalegui, Federico; Belli, Carolina; Atorrasagasti Fernández, María Catalina; Miriuka, Santiago Gabriel; Moro, Lucía Natalia (Elsevier, 2023-06-25)
    The arrhythmogenic cardiomyopathy (ACM) is an inherited heart muscle disease characterized by the progressive replacement of contractile myocardium by fibro-fatty adipose tissue, that generates ventricular arrhythmias and ...
  • Rosato-Siri, María Victoria; Martino Adami, Pamela V.; Guitart, María Eugenia; Verstraeten, Sandra V.; Morelli, Laura; Correale, Jorge; Pasquini, Juana María (Humana Press, 2023-01-03)
    Iron deficiency (ID) represents one of the most prevalent nutritional deficits, affecting almost two billion people worldwide. Gestational iron deprivation induces hypomyelination due to oligodendroglial maturation ...
  • Adler, Melanie Victoria; Fialá Sánchez, Mariana; Martini, Constanza; Vartabedian, Luciana Mariam; Zazzali, Matías Nicolás; Quintero Rincón, Antonio (Sociedad Argentina de Bioingeniería, 2020)
    Bone conduction is the transmission of acoustic energy to the inner ear by different paths involving the bones of the skull. In this work, we use the path the hand provides in order to transmit the sound coming from the ...
  • Freiberger, Rosa Nicole; López, Cynthia Alicia Marcela; Palma, María Belén; Cevallos, Cintia; Sviercz, Franco Agustin; Jarmolu, Patricio; García, Marcela Nilda; Quarleri, Jorge; Delpino, M. Victoria (MDPI AG, 2024-09-15)
    Bone loss is a prevalent characteristic among people with HIV (PWH). We focused on mesenchymal stem cells (MSCs) and osteoblasts, examining their susceptibility to different HIV strains (R5- and X4-tropic) and the subsequent ...
  • Palma, María Belén; Tronik-Le Roux, Diana; Amín, Guadalupe; Castañeda, Sheila; Möbbs, Alan Miqueas; Scarafía, María Agustina; La Greca, Alejandro; Daouya, Marina; Poras, Isabelle; Inda, Ana María; Moro, Lucía Natalia; Carosella, Edgardo D.; García, Marcela N.; Miriuka, Santiago Gabriel (bioRxiv, 2021-01-22)
    Cancer immunotherapies based mainly on the blockade of immune-checkpoint (IC) molecules by anti-IC antibodies offer new alternatives for treatment in oncological diseases. However, a considerable proportion of patients ...
  • Videla Richardson, Guillermo Agustín; Furmento, Verónica Alejandra; García, Carolina Paola; Morris-Hanon, Olivia; Sevlever, Gustavo Emilio; Romorini, Leonardo; Scassa, María Élida (Biomed Central, 2019-08-28)
    BACKGROUND: The essentially unlimited expansion potential and the pluripotency of human embryonic stem cells (hESCs) make them attractive for cell-based therapeutic purposes. Although hESCs can indefinitely proliferate ...
  • Neiman, Gabriel; Scarafía, María Agustina; La Greca, Alejandro; Santín Velazque, Natalia Lucía; Garate, Ximena; Waisman, Ariel; Möbbs, Alan Miqueas; Kasai-Brunswick, Tais Hanae; Mesquita, Fernanda C.P.; Martire-Greco, Daiana; Moro, Lucía Natalia; Luzzani, Carlos Daniel; Bastos Carvalho, Adriana; Sevlever, Gustavo Emilio; Campos de Carvalho, Antonio C.; Guberman, Alejandra S.; Miriuka, Santiago Gabriel (Nature Publishing Group, 2019-12-02)
    The stem cell niche has a strong influence in the differentiation potential of human pluripotent stem cells with integrins playing a major role in communicating cells with the extracellular environment. However, it is not ...
  • Marcora, María Silvina; Mattera, Vanesa S.; Goñi, Pilar; Aybar, Florencia; Correale, Jorge; Pasquini, Juana María (Wiley Interscience, 2024-04)
    Iron deficiency (ID) has been shown to affect central nervous system (CNS) development and induce hypomyelination. Previous work from our laboratory in a gestational ID model showed that both oligodendrocyte (OLG) and ...
  • Cosentino, María Soledad; Oses, Camila; Vázquez Echegaray, Camila; Solari, Claudia; Waisman, Ariel; Álvarez, Yanina; Petrone, María Victoria; Francia, Marcos; Schultz, Marcelo; Sevlever, Gustavo Emilio; Miriuka, Santiago Gabriel; Levi, Valeria; Guberman, Alejandra S. (Academic Press, 2019-03-15)
    Chromatin remodeling is fundamental for the dynamical changes in transcriptional programs that occur during development and stem cell differentiation. The histone acetyltransferase Kat6b is relevant for neurogenesis in ...

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