Neurociencias.artículos: Recent submissions

  • Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness 
    Sanz Perl, Yonatan; Pallavicini, Carla; Pérez Ipiña, Ignacio; Demertzi, Athena; Bonhomme, Vincent; Martial, Charlotte; Panda, Rajanikant; Annen, Jitka; Ibañez, Agustín; Kringelbach, Morten; Deco, Gustavo; Laufs, Helmut; Sitt, Jacobo D.; Laureys, Steven; Tagliazucchi, Enzo (Public Library of Science, 2021-07-27)
    Consciousness transiently fades away during deep sleep, more stably under anesthesia, and sometimes permanently due to brain injury. The development of an index to quantify the level of consciousness across these different ...
  • SUMO conjugation susceptibility of Akt/protein kinase B affects the expression of the pluripotency transcription factor Nanog in embryonic stem cells 
    Francia, Marcos; Stortz, Martin; Vazquez Echegaray, Camila; Oses, Camila; Verneri, Paula; Petrone, María Victoria; Toro, Ayelén; Waisman, Ariel; Miriuka, Santiago Gabriel; Cosentino, María Soledad; Levi, Valeria; Guberman, Alejandra S. (Public Library of Science, 2021-07-09)
    Akt/PKB is a kinase involved in the regulation of a wide variety of cell processes. Its activity is modulated by diverse post-translational modifications (PTMs). Particularly, conjugation of the small ubiquitin-related ...
  • Hand bone conduction sound study by using the DSP Logger MX 300 
    Adler, Melanie Victoria; Fialá Sánchez, Mariana; Martini, Constanza; Vartabedian, Luciana Mariam; Zazzali, Matías Nicolás; Quintero Rincón, Antonio (Sociedad Argentina de Bioingeniería, 2020)
    Bone conduction is the transmission of acoustic energy to the inner ear by different paths involving the bones of the skull. In this work, we use the path the hand provides in order to transmit the sound coming from the ...
  • celldeath: A tool for detection of cell death in transmitted light microscopy images by deep learning-based visual recognition 
    La Greca, Alejandro; Pérez, Nelba; Castañeda, Sheila; Milone, Paula Melania; Scarafía, María Agustina; Möbbs, Alan Miqueas; Waisman, Ariel; Moro, Lucía Natalia; Sevlever, Gustavo Emilio; Luzzani, Carlos Daniel; Miriuka, Santiago Gabriel (Public Library of Science, 2021-06-24)
    Cell death experiments are routinely done in many labs around the world, these experiments are the backbone of many assays for drug development. Cell death detection is usually performed in many ways, and requires time and ...
  • Neurobiological substrates underlying corpus callosum hypoconnectivity and brain metabolic patterns in the valproic acid rat model of autism spectrum disorder 
    Uccelli, Nonthué Alejandra; Codagnone, Martín Gabriel; Traetta, Marianela Evelyn; Levanovich, Nadia; Rosato-Siri, María Victoria; Urrutia, Leandro; Falasco, Germán; Vázquez, Silvia; Pasquini, Juana María; Reinés, Analía Gabriela (Wiley, 2021-06-03)
    Atypical connectivity between brain regions and altered structure of the corpus callosum (CC) in imaging studies support the long-distance hypoconnectivity hypothesis proposed for autism spectrum disorder (ASD). The aim ...
  • Tau mis-splicing correlates with motor impairments and striatal dysfunction in a model of tauopathy 
    Damianich, Ana; Facal, Carolina Lucía; Muñiz, Javier Andrés; Mininni, Camilo; Soiza Reilly, Mariano; Ponce de León, Magdalena; Urrutia, Leandro; Falasco, Germán; Ferrario, Juan Esteban; Avale, María Elena (Oxford, 2021-06-01)
    Tauopathies are neurodegenerative diseases caused by the abnormal metabolism of the microtubule associated protein Tau, which is highly expressed in neurons and critically involved in microtubule dynamics. In the adult ...
  • Wound Healing by Allogeneic Transplantation of Specific Subpopulation From Human Umbilical Cord Mesenchymal Stem Cells 
    Palma, María Belén; Luzzani, Carlos Daniel; Andrini, Laura B.; Riccillo, Fernando; Buero, Guillermo; Pelinski, Pablo; Inda, Ana María; Errecalde, Ana Lía; Miriuka, Santiago Gabriel; Carosella, Edgardo D.; Garcia, Marcela N. (Sage, 2021-05-11)
    In normal physiological conditions, restoration of a functional epidermal barrier is highly efficient; nevertheless, when it fails, one of the main consequences is a chronic ulcerative skin defect, one of the most frequently ...
  • Lifetime use of psychedelics is associated with better mental health indicators during the COVID-19 pandemic 
    Cavanna, Federico; Pallavicini, Carla; Milano, Virginia; Cuiule, Juan Manuel; Di Tella, Rocco; González, Pablo; Tagliazucchi, Enzo (Akadémiai Kiadó, 2021-05-04)
    Background and aims: The COVID-19 pandemic and its consequences represent a major challenge to the mental health and well-being of the general population. Building on previous work on the potential long-term benefits of ...
  • Data augmentation based on dynamical systems for the classification of brain states 
    Sanz Perl, Yonatan; Pallavicini, Carla; Perez Ipiña, Ignacio; Kringelbach, Morten; Deco, Gustavo; Laufs, Helmut; Tagliazucchi, Enzo (Elsevier, 2020-07-10)
    The application of machine learning algorithms to neuroimaging data shows great promise for the classification of physiological and pathological brain states. However, classifiers trained on high dimensional data are prone ...
  • Generation of myostatin edited horse embryos using CRISPR/Cas9 technology and somatic cell nuclear transfer 
    Moro, Lucía Natalia; Viale, Diego Luis; Bastón, Juan Ignacio; Arnold, Victoria; Suva, Mariana; Wiedenmann, Elisabet; Olguín, Martín; Miriuka, Santiago Gabriel; Vichera, Gabriel (Nature Publishing Group, 2020-08-24)
    The application of new technologies for gene editing in horses may allow the generation of improved sportive individuals. Here, we aimed to knock out the myostatin gene (MSTN), a negative regulator of muscle mass development, ...
  • Optic tract and internal capsule lesion in a patient with Wernicke-Korsakoff syndrome 
    Hernández, Micaela Anahí; Varela, Francisco José; Bensi, Catalina (Universidad de la Costa, 2020-12-07)
    A 72-year-old man, presented with a one-week history of confusion and an anterograde amnesic disorder accompanied by confabulation, with lack of insight to his symptoms. Medical history included alcohol abuse and admitted ...
  • Chemical hypoxia induces apoptosis of human pluripotent stem cells by a NOXA-mediated HIF-1α and HIF-2α independent mechanism 
    Isaja, Luciana; Mucci, Sofía; Vera, Jonathan; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Morris-Hanon, Olivia; Videla Richardson, Guillermo Agustín; Sevlever, Gustavo Emilio; Scassa, María Élida; Romorini, Leonardo (Nature Publishing Group, 2020-10-26)
    Human embryonic and induced pluripotent stem cells (hESCs and hiPSCs) are self-renewing human pluripotent stem cells (hPSCs) that can differentiate to a wide range of specialized cells. Notably, hPSCs enhance their ...
  • Author Correction: AHR is a Zika virus host factor and a candidate target for antiviral therapy 
    Giovannoni, Federico; Bosch, Irene; Manganeli Polonio, Carolina; Torti, María F.; Wheeler, Michael A.; Li, Zhaorong; Romorini, Leonardo; Rodríguez Varela, María Soledad; Rothhammer, Veit; Barroso, Andreia; Tjon, Emily C.; Sanmarco, Liliana M.; Takenaka, Maisa C.; Sadegh Modaresi, Seyed Mohamad; Gutiérrez-Vázquez, Cristina; Ghabdan Zanluqui, Nágela; Barreto Dos Santos, Nilton; Demarchi Munhoz, Carolina; Wang, Zhongyan; Damonte, Elsa B.; Sherr, David; Gehrke, Lee; Schatzmann Peron, Jean Pierre; Garcia, Cybele C.; Quintana, Francisco J. (Nature Publishing Group, 2020-10)
  • The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma 
    García, Marcela N.; Palma, María Belén; Verine, Jerome; Miriuka, Santiago Gabriel; Inda, Ana María; Errecalde, Ana Lía; Desgrandchamps, François; Carosella, Edgardo D.; Tronik-Le Roux, Diana (BioMed Central, 2020-07-03)
    Background: Clear cell renal cell carcinoma (ccRCC), the most aggressive renal cancer, is characterized by early lymph node metastases and bad prognosis. Most therapies targeting advanced or metastatic ccRCC are based, as ...
  • Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient 
    Isaja, Luciana; Rodríguez Varela, María Soledad; Marazita, Mariela Claudia; Mucci, Sofía; Itzcovich, Tatiana; Chrem Méndez, Patricio Alexis; Niikado, Matías; Ferriol Laffouillere, Sofía Luján; Allegri, Ricardo Francisco; Martinetto, Horacio; Sevlever, Gustavo Emilio; Scassa, María Élida; Surace, Ezequiel Ignacio; Romorini, Leonardo (Elsevier, 2021-04-05)
    Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained from a skin biopsy of a 72-year-old Caucasian male ...
  • Distinct Neural Processing of Acute Stress in Major Depression and Borderline Personality Disorder 
    Villarreal, Mirta Fabiana; Wainsztein, Agustina Edith; Álvarez Mercé, Rocío; Goldberg, Ximena; Castro, Mariana Nair; Brusco, Luis Ignacio; Ladrón de Guevara, Soledad; Bodurka, Jerzy; Paulus, Martin; Menchón, José Manuel; Soriano-Mas, Carles; Guinjoan, Salvador Martín (Elsevier, 2021-02-26)
    Background: Major depressive disorder (MDD) and borderline personality disorder (BPD) are highly prevalent and often comorbid psychiatric conditions, with abnormal processing of negative affect resulting from psychological ...
  • Extraction-free protocol combining proteinase K and heat inactivation for detection of SARS-CoV-2 by RT-qPCR 
    Genoud, Valeria; Stortz, Martin; Waisman, Ariel; Berardino, Bruno G.; Verneri, Paula; Dansey, Virginia; Salvatori, Melina; Remes Lenicov, Federico; Levi, Valeria (PLoS One, 2021-02-26)
    Real-time reverse transcription PCR (RT-qPCR) is the gold-standard technique for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection in nasopharyngeal swabs specimens. The analysis by RT-qPCR usually ...
  • Towards the Journal of Applied Cognitive Neuroscience 
    Allegri, Ricardo Francisco; Roman, Fabián; Barceló Martínez, Ernesto (Universidad de la Costa, 2020-12-07)
    In his book The Structure of Science Evolution, Thomas Khum defines a paradigmas “a set of beliefs, values and accepted techniques that define the exercise of a scientific discipline”. A new paradigm is a change of vision, ...
  • Neural and subjective effects of inhaled N,N-dimethyltryptamine in natural settings 
    Pallavicini, Carla; Cavanna, Federico; Zamberlan, Federico; de la Fuente, Laura A.; Ilksoy, Yayla; Perl, Yonatan Sanz; Arias, Mauricio; Romero, Celeste; Carhart-Harris, Robin; Timmermann, Christopher; Tagliazucchi, Enzo (Sage, 2021-02-10)
    Background: N,N-dimethyltryptamine is a short-acting psychedelic tryptamine found naturally in many plants and animals. Few studies to date have addressed the neural and psychological effects of N,N-dimethyltryptamine ...
  • Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle 
    Waisman, Ariel; Norris, Alessandra; Costa, Martín Elías; Kopinke, Daniel (Nature Publishing Group, 2021-01-22)
    Skeletal muscle has the remarkable ability to regenerate. However, with age and disease muscle strength and function decline. Myofiber size, which is affected by injury and disease, is a critical measurement to assess ...

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