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Bilateral facial palsy with paresthesias, variant of Guillain-Barré syndrome following COVID-19 vaccine: A case series of 9 patients

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dc.contributor.author Castiglione, Juan Ignacio
dc.contributor.author Crespo, Marcos José
dc.contributor.author Lecchini, Lucila
dc.contributor.author Silveira, F.O.
dc.contributor.author Luis, María Belén
dc.contributor.author Cotti, Norberto
dc.contributor.author Simison, Conrado J.
dc.contributor.author Aguirre, Florencia
dc.contributor.author Piedrabuena, María Agustina
dc.contributor.author Alonso, R. N.
dc.contributor.author Azcona, Carolina Laura
dc.contributor.author Sosa, Pablo Sebastian
dc.contributor.author Maldonado, Evangelina
dc.contributor.author Barroso, Fabio Adrián
dc.date.accessioned 2023-01-05T12:31:52Z
dc.date.available 2023-01-05T12:31:52Z
dc.date.issued 2022-07
dc.identifier.citation Castiglione JI, Crespo JM, Lecchini L, Silveira FO, Luis MB, Cotti N, Simison CJ, Aguirre F, Piedrabuena MA, Alonso RN, Azcona CL, Sosa PS, Maldonado E, Barroso F. Bilateral facial palsy with paresthesias, variant of Guillain-Barré syndrome following COVID-19 vaccine: A case series of 9 patients. Neuromuscul Disord. 2022 Jul;32(7):572-574. doi: 10.1016/j.nmd.2022.05.003. Epub 2022 May 11. es_ES
dc.identifier.uri https://doi.org/10.1016/j.nmd.2022.05.003
dc.identifier.uri https://repositorio.fleni.org.ar/xmlui/handle/123456789/757
dc.description.abstract Several cases of Guillain-Barré Syndrome (GBS) associated with COVID-19 vaccination have been reported, including the rare subtype known as Bilateral Facial Palsy with paresthesias (BFP). To date, it is not known whether a causal relationship may exist between the two. We report 9 cases of BFP in patients vaccinated against COVID-19 in the previous month. Nerve conduction studies revealed demyelinating polyneuropathy in 4 patients, and 5 presented bilateral, focal facial nerve involvement, exclusively. Ganglioside antibody panel was positive in 4 patients (anti-GM1=2, anti-GD1a=1 and anti-sulfatide=1). Seven patients received intravenous immunoglobulin treatment, one plasma exchange, and one patient died from sudden cardiac arrest following arrhythmia before treatment could be administered. Rates of BFP following COVID-19 vaccination, did not differ from those reported in previous series. Epidemiological studies are essential to determine whether a causal relationship may exist between this rare form of GBS and COVID-19 vaccination. es_ES
dc.language.iso eng es_ES
dc.publisher Pergamon Press es_ES
dc.rights info:eu-repo/semantics/openAccess
dc.rights.uri https://creativecommons.org/licenses/by/2.5/ar/
dc.subject Facial Paralysis es_ES
dc.subject Parálisis Facial es_ES
dc.subject COVID-19 Vaccines es_ES
dc.subject Vacunas contra la COVID-19 es_ES
dc.subject Guillain-Barre Syndrome es_ES
dc.subject Síndrome de Guillain-Barré es_ES
dc.title Bilateral facial palsy with paresthesias, variant of Guillain-Barré syndrome following COVID-19 vaccine: A case series of 9 patients es_ES
dc.type info:eu-repo/semantics/article es_ES
dc.type info:eu-repo/semantics/publishedVersion
dc.description.fil Fil: Castiglione, Juan Ignacio. Fleni. Departamento de Neurología; Argentina.
dc.description.fil Fil: Crespo, Marcos José. Fleni. Departamento de Neurología; Argentina.
dc.description.fil Fil: Barroso, Fabio Adrián. Fleni. Departamento de Neurología; Argentina.
dc.description.fil Fil: Lecchini, L. Hospital Nacional Alejandro Posadas; Argentina.
dc.description.fil Fil: Silveira, F.O. Hospital Italiano de Buenos Aires; Argentina.
dc.description.fil Fil: Luis, M.B. Sanatorio Güemes; Argentina.
dc.description.fil Fil: Cotti, N. Sanatorio de los Arcos; Argentina.
dc.description.fil Fil: Simison, C.J. Hospital J.M. Ramos Mejía; Argentina.
dc.description.fil Fil: Aguirre, Florencia. Hospital J.M. Ramos Mejía; Argentina.
dc.description.fil Fil: Piedrabuena, María Agustina. Sanatorio Güemes; Argentina.
dc.description.fil Fil: Alonso, R.N. Sanatorio Güemes; Argentina.
dc.description.fil Fil: Azcona, C.L. Hospital Italiano de Buenos Aires; Argentina.
dc.description.fil Fil: Sosa, P.S. Hospital Italiano de Buenos Aires; Argentina.
dc.description.fil Fil: Maldonado, E. Hospital Nacional Alejandro Posadas; Argentina.
dc.relation.ispartofVOLUME 32
dc.relation.ispartofNUMBER 7
dc.relation.ispartofPAGINATION 572-574.
dc.relation.ispartofCOUNTRY Inglaterra
dc.relation.ispartofCITY Nueva York
dc.relation.ispartofTITLE Neuromuscular disorders : NMD
dc.relation.ispartofISSN 1873-2364
dc.type.snrd info:ar-repo/semantics/artículo es_ES


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