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Browsing INEU by Author "Chhatwal, Jasmeer P."

Browsing INEU by Author "Chhatwal, Jasmeer P."

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  • Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome 
    Gorijala, Priyanka; Aslam, M. Muaaz; Dang, Lam-Ha T.; Xicota, L.; Fernández, María V.; Sung, Yun Ju; Fan, Kang-Hsien; Feingold, Eleanor; Surace, Ezequiel Ignacio; Chhatwal, Jasmeer P.; Hom, Christy L.; Dominantly Inherited Alzheimer Network; NIA-LOAD family study, for the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) Investigators; Hartley, Sigan L.; Hassenstab, Jason; Perrin, Richard J.; Mapstone, Mark; Zaman, Shahid H.; Ances, Beau M.; Kamboh, M. Ilyas; Lee, Joseph H.; Cruchaga, Carlos (John Wiley & Sons, 2023-10-19)
    Introduction: This study aimed to investigate the influence of the overall Alzheimer's disease (AD) genetic architecture on Down syndrome (DS) status, cognitive measures, and cerebrospinal fluid (CSF) biomarkers. Methods: ...
  • Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology 
    Morris, John C.; Weiner, Michael W.; Xiong, Chengjie; Beckett, Laurel A.; Coble, Dean; Saito, Naomi; Aisen, Paul S.; Allegri, Ricardo Francisco; Benzinger, Tammie L.S.; Berman, Sarah B.; Cairns, Nigel; Carrillo, María C.; Chui, Helena C.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin R.; Fox, Nick C.; Ghetti, Bernardino; Goate, Alison M. (Oxford University Press, 2022-10-21)
    The extent to which the pathophysiology of autosomal dominant Alzheimer's disease corresponds to the pathophysiology of 'sporadic' late onset Alzheimer's disease is unknown, thus limiting the extrapolation of study findings ...
  • Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease 
    Horie, Kanta; Li, Yan; Barthélemy, Nicolas R.; Gordon, Brian A.; Hassenstab, Jason; Benzinger, Tammie L.S.; Fagan, Anne M.; Morris, John C.; Karch, Celeste M.; Xiong, Chengjie; Allegri, Ricardo Francisco; Chrem Méndez, Patricio Alexis; Ikeuchi, Takeshi; Kasuga, Kensaku; Noble, James M.; Farlow, Martin R.; Chhatwal, Jasmeer P.; Day, Gregory S.; Schofield, Peter R.; Dominantly Inherited Alzheimer Network (Wiley, 2023-03-16)
    Objective: Identifying cerebrospinal fluid measures of the microtubule binding region of tau (MTBR-tau) species that reflect tau aggregation could provide fluid biomarkers that track Alzheimer's disease related neurofibrillary ...
  • Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease 
    Allegri, Ricardo Francisco; Dincer, Aylin; Gordon, Brian A.; Hari-Raj, Amrita; Keefe, Sarah J.; Flores, Shaney; McKay, Nicole S.; Paulick, Angela M.; Shady Lewis, Kristine E.; Feldman, Rebecca L.; Hornbeck, Russ C.; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Chhatwal, Jasmeer P.; Farlow, Martin R.; La Fougère, Christian; Fox, Nick C.; Fulham, Michael J.; Jack Jr, Clifford R.; Joseph-Mathurin, Nelly; Karch, Celeste M.; Lee, Athene; Levin, Johannes; Masters, Colin L.; McDade, Eric; Oh, Hwamee; Perrin, Richard J.; Raji, Cyrus; Salloway, Stephen; Schofield, Peter R.; Su, Yi; Villemagne, Victor L.; Wang, Qing; Weiner, Michael W.; Xiong, Chengjie; Yakushev, Igor; Morris, John C.; Bateman, Randall J.; Benzinger, Tammie L.S.; Dominantly Inherited Alzheimer Network (Elsevier, 2020-11-05)
    Defining a signature of cortical regions of interest preferentially affected by Alzheimer disease (AD) pathology may offer improved sensitivity to early AD compared to hippocampal volume or mesial temporal lobe alone. Since ...
  • Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid 
    Drieu, Antoine; Du, Siling; Storck, Steffen E.; Rustenhoven, Justin; Papadopoulos, Zachary; Dykstra, Taitea; Zhong, Fenghe; Kim, Kyungdeok; Blackburn, Susan; Mamuladze, Tornike; Harari, Oscar; Karch, Celeste M.; Bateman, Randall J.; Perrin, Richard J.; Farlow, Martin R.; Chhatwal, Jasmeer P.; Dominantly Inherited Alzheimer Network; Hu, Song; Randolph, Gwendalyn J.; Allegri, Ricardo Francisco (Nature Publishing Group, 2022-11)
    Macrophages are important players in the maintenance of tissue homeostasis1. Perivascular and leptomeningeal macrophages reside near the central nervous system (CNS) parenchyma2, and their role in CNS physiology has not ...

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